FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3157661821> ?p ?o ?g. }

• W3157661821 abstract "ABSTRACT Almond consumption can improve cardiometabolic (CM) health. However, the mechanisms underlying those benefits are not well characterized. This study explored the effects of consuming a snack of almonds vs. crackers for 8 weeks on changes in metabolomic profiles in young adults ( clinicaltrials.gov ID: NCT03084003 ). Participants (n=73, age: 18-19 years, BMI: 18-41 kg/m2) were randomly assigned to consume either almonds (2 oz/d, n=38) or an isocaloric control snack of graham crackers (325 kcal/d, n=35) daily for 8 weeks. Blood samples were collected at baseline prior to and at 4 and 8 weeks after the intervention. Metabolite abundances in the serum were quantified by hydrophilic interaction chromatography quadrupole (Q) time-of-flight (TOF) mass spectrometry (MS/MS), gas chromatography (GC) TOF MS, CSH-ESI (electrospray) QTOF MS/MS, and targeted analyses for free PUFAs, total fatty acids, oxylipins and endocannabinoids. Linear mixed model analyses with baseline-adjustment were conducted, and those results were used for enrichment and network analyses. Microbial community pathway predictions from 16S rRNA sequencing of fecal samples was done using PICRUST2. Almond consumption enriched unsaturated triglycerides, unsaturated phosphatidylcholines, saturated and unsaturated lysophosphatidylcholines, tricarboxylic acids, and tocopherol clusters (p<0.05). Targeted analyses reveal lower levels of omega-3 total fatty acids (TFAs) overall in the almond group compared to the cracker group (p<0.05). Microbial amino acid biosynthesis, and amino sugar and nucleotide sugar metabolism pathways were also differentially enriched at the end of the intervention (p<0.05). The study demonstrates the differential effects of almonds on host tocopherol, lipid, and TCA cycle metabolism with potential changes in microbial metabolism, which may interact with host metabolism to facilitate the CM benefits." @default.
• W3157661821 created "2021-05-10" @default.
• W3157661821 creator A5036162154 @default.
• W3157661821 creator A5057567274 @default.
• W3157661821 creator A5085030272 @default.
• W3157661821 creator A5087349635 @default.
• W3157661821 date "2021-05-05" @default.
• W3157661821 modified "2023-10-16" @default.
• W3157661821 title "Almond Consumption for 8 Weeks Altered Host and Microbial Metabolism in Comparison to a Control Snack in Young Adults" @default.
• W3157661821 cites W1597941165 @default.
• W3157661821 cites W1789946263 @default.
• W3157661821 cites W1850084715 @default.
• W3157661821 cites W1863654876 @default.
• W3157661821 cites W1940935006 @default.
• W3157661821 cites W1973415310 @default.
• W3157661821 cites W1989012351 @default.
• W3157661821 cites W1995719589 @default.
• W3157661821 cites W2000770184 @default.
• W3157661821 cites W2002738268 @default.
• W3157661821 cites W2004760389 @default.
• W3157661821 cites W2028151674 @default.
• W3157661821 cites W2028600248 @default.
• W3157661821 cites W2033640987 @default.
• W3157661821 cites W2050135062 @default.
• W3157661821 cites W2050963348 @default.
• W3157661821 cites W2052036460 @default.
• W3157661821 cites W2053313299 @default.
• W3157661821 cites W2056433232 @default.
• W3157661821 cites W2070391080 @default.
• W3157661821 cites W2070635899 @default.
• W3157661821 cites W2075397364 @default.
• W3157661821 cites W2077631777 @default.
• W3157661821 cites W2091745405 @default.
• W3157661821 cites W2099451866 @default.
• W3157661821 cites W2113177287 @default.
• W3157661821 cites W2120469313 @default.
• W3157661821 cites W2120929142 @default.
• W3157661821 cites W2125924498 @default.
• W3157661821 cites W2137526110 @default.
• W3157661821 cites W2140759372 @default.
• W3157661821 cites W2145546477 @default.
• W3157661821 cites W2146512944 @default.
• W3157661821 cites W2152007541 @default.
• W3157661821 cites W2152805980 @default.
• W3157661821 cites W2153615428 @default.
• W3157661821 cites W2159675211 @default.
• W3157661821 cites W2165891030 @default.
• W3157661821 cites W2167315466 @default.
• W3157661821 cites W2167376541 @default.
• W3157661821 cites W2262277611 @default.
• W3157661821 cites W2312881855 @default.
• W3157661821 cites W2323134307 @default.
• W3157661821 cites W2339856074 @default.
• W3157661821 cites W2497359825 @default.
• W3157661821 cites W2607213693 @default.
• W3157661821 cites W2636477438 @default.
• W3157661821 cites W2739475138 @default.
• W3157661821 cites W2753789151 @default.
• W3157661821 cites W2883499165 @default.
• W3157661821 cites W2903308268 @default.
• W3157661821 cites W2913413642 @default.
• W3157661821 cites W2919002166 @default.
• W3157661821 cites W2922487676 @default.
• W3157661821 cites W2955266153 @default.
• W3157661821 cites W2990644537 @default.
• W3157661821 cites W3005849052 @default.
• W3157661821 cites W3042825209 @default.
• W3157661821 doi "https://doi.org/10.1101/2021.05.03.21256353" @default.
• W3157661821 hasPublicationYear "2021" @default.
• W3157661821 type Work @default.
• W3157661821 sameAs 3157661821 @default.
• W3157661821 citedByCount "0" @default.
• W3157661821 crossrefType "posted-content" @default.
• W3157661821 hasAuthorship W3157661821A5036162154 @default.
• W3157661821 hasAuthorship W3157661821A5057567274 @default.
• W3157661821 hasAuthorship W3157661821A5085030272 @default.
• W3157661821 hasAuthorship W3157661821A5087349635 @default.
• W3157661821 hasBestOaLocation W31576618211 @default.
• W3157661821 hasConcept C185592680 @default.
• W3157661821 hasConcept C19038510 @default.
• W3157661821 hasConcept C21565614 @default.
• W3157661821 hasConcept C2777108408 @default.
• W3157661821 hasConcept C2777477808 @default.
• W3157661821 hasConcept C31903555 @default.
• W3157661821 hasConcept C43617362 @default.
• W3157661821 hasConcept C543025807 @default.
• W3157661821 hasConcept C55493867 @default.
• W3157661821 hasConcept C62231903 @default.
• W3157661821 hasConceptScore W3157661821C185592680 @default.
• W3157661821 hasConceptScore W3157661821C19038510 @default.
• W3157661821 hasConceptScore W3157661821C21565614 @default.
• W3157661821 hasConceptScore W3157661821C2777108408 @default.
• W3157661821 hasConceptScore W3157661821C2777477808 @default.
• W3157661821 hasConceptScore W3157661821C31903555 @default.
• W3157661821 hasConceptScore W3157661821C43617362 @default.
• W3157661821 hasConceptScore W3157661821C543025807 @default.
• W3157661821 hasConceptScore W3157661821C55493867 @default.
• W3157661821 hasConceptScore W3157661821C62231903 @default.
• W3157661821 hasLocation W31576618211 @default.
• W3157661821 hasLocation W31576618212 @default.

• next