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- W3157663648 abstract "Abstract Background Wolbachia is an obligate intracellular maternally transmitted, gram-negative bacterium which forms a spectrum of endosymbiotic relationships from parasitism to obligatory mutualism in a wide range of arthropods and onchocercid nematodes, respectively. In arthropods Wolbachia produces reproductive manipulations such as male killing, feminization, parthenogenesis and cytoplasmic incompatibility for its propagation and provides an additional fitness benefit for the host to protect against pathogens, whilst in onchocercid nematodes, apart from the mutual metabolic dependence, this bacterium is involved in moulting, embryogenesis, growth and survival of the host. Methods This review details the molecular data of Wolbachia and its effect on host biology, immunity, ecology and evolution, reproduction, endosymbiont-based treatment and control strategies exploited for filariasis. Relevant peer-reviewed scientic papers available in various authenticated scientific data bases were considered while writing the review. Conclusions The information presented provides an overview on Wolbachia biology and its use in the control and/or treatment of vectors, onchocercid nematodes and viral diseases of medical and veterinary importance. This offers the development of new approaches for the control of a variety of vector-borne diseases. Graphical Abstract" @default.
- W3157663648 created "2021-05-10" @default.
- W3157663648 creator A5049120075 @default.
- W3157663648 creator A5057623985 @default.
- W3157663648 creator A5075077614 @default.
- W3157663648 creator A5076529350 @default.
- W3157663648 date "2021-05-07" @default.
- W3157663648 modified "2023-10-12" @default.
- W3157663648 title "Wolbachia: endosymbiont of onchocercid nematodes and their vectors" @default.
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