FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3157705493> ?p ?o ?g. }

• W3157705493 abstract "Abstract Curtailing the absorption of triglycerides (TGs) is a preferred pathway for treating obesity. Our previous study demonstrated that the water-soluble fraction from potato could inhibit the lipase activity of patatin, one of the major proteins in potato. This aqueous fraction was purified and concentrated by deproteination and reversed-phase chromatography to investigate the effectiveness against obesity. Biochemical analyses indicated that the fraction non-competitively inhibited pancreatic lipase (PLase) with a half-maximal inhibitory concentration of 10.17 µg/mL, and was named as potato-derived lipase inhibitory fraction (PI). Animal studies on C57BL/6 mice showed that in mice fed a high-fat diet (HFD), PI treatment resulted in reductions in body weight gain, adipose fat deposition, and liver TGs, and ameliorated the gut microbiome dysbiosis caused by HFD feeding; meanwhile, orlistat, a well-known lipase inhibitor, diverged the gut microbiome profile in mice fed a HFD. High resolution electronspray ionization-Orbitrap tandem mass spectrometry identified gallic acid, 4-hydroxybenzoic acid, and protocatechuic acid, which are known to have lipase inhibitory activities, in PI. However, these compounds could not reconstitute comparable specific inhibitory activity of PI inferring the existence of another inhibitory compound(s) to be identified in PI." @default.
• W3157705493 created "2021-05-10" @default.
• W3157705493 creator A5009885204 @default.
• W3157705493 creator A5033268650 @default.
• W3157705493 creator A5052160854 @default.
• W3157705493 creator A5068923111 @default.
• W3157705493 creator A5068974995 @default.
• W3157705493 date "2021-02-09" @default.
• W3157705493 modified "2023-09-24" @default.
• W3157705493 title "Potato extract inhibits lipase activity and ameliorates gut microbiome dysbiosis and weight gain in mice fed a high-fat diet" @default.
• W3157705493 cites W1132787879 @default.
• W3157705493 cites W1827500364 @default.
• W3157705493 cites W1851361856 @default.
• W3157705493 cites W1980005304 @default.
• W3157705493 cites W1993689943 @default.
• W3157705493 cites W1994698749 @default.
• W3157705493 cites W1996119665 @default.
• W3157705493 cites W2001633956 @default.
• W3157705493 cites W2009803502 @default.
• W3157705493 cites W2017243716 @default.
• W3157705493 cites W2019419945 @default.
• W3157705493 cites W2050259497 @default.
• W3157705493 cites W2055515746 @default.
• W3157705493 cites W2068634811 @default.
• W3157705493 cites W2073332363 @default.
• W3157705493 cites W2079612622 @default.
• W3157705493 cites W2079929562 @default.
• W3157705493 cites W2127303481 @default.
• W3157705493 cites W2136993578 @default.
• W3157705493 cites W2153538626 @default.
• W3157705493 cites W2166449272 @default.
• W3157705493 cites W2167062509 @default.
• W3157705493 cites W2472690798 @default.
• W3157705493 cites W2511112097 @default.
• W3157705493 cites W2772054897 @default.
• W3157705493 cites W2772176268 @default.
• W3157705493 cites W2799699133 @default.
• W3157705493 cites W2803440369 @default.
• W3157705493 cites W2884495027 @default.
• W3157705493 cites W2895795611 @default.
• W3157705493 cites W2897063882 @default.
• W3157705493 cites W2904286439 @default.
• W3157705493 cites W2905370102 @default.
• W3157705493 cites W2906801816 @default.
• W3157705493 cites W2942641201 @default.
• W3157705493 cites W2949364854 @default.
• W3157705493 cites W2974969849 @default.
• W3157705493 cites W2982623437 @default.
• W3157705493 cites W2996785814 @default.
• W3157705493 cites W2997701025 @default.
• W3157705493 cites W3006236807 @default.
• W3157705493 cites W3016004687 @default.
• W3157705493 cites W3017187929 @default.
• W3157705493 cites W3031135551 @default.
• W3157705493 cites W3033043724 @default.
• W3157705493 cites W3034040497 @default.
• W3157705493 cites W762432959 @default.
• W3157705493 doi "https://doi.org/10.1186/s13765-021-00590-w" @default.
• W3157705493 hasPublicationYear "2021" @default.
• W3157705493 type Work @default.
• W3157705493 sameAs 3157705493 @default.
• W3157705493 citedByCount "3" @default.
• W3157705493 countsByYear W31577054932022 @default.
• W3157705493 countsByYear W31577054932023 @default.
• W3157705493 crossrefType "journal-article" @default.
• W3157705493 hasAuthorship W3157705493A5009885204 @default.
• W3157705493 hasAuthorship W3157705493A5033268650 @default.
• W3157705493 hasAuthorship W3157705493A5052160854 @default.
• W3157705493 hasAuthorship W3157705493A5068923111 @default.
• W3157705493 hasAuthorship W3157705493A5068974995 @default.
• W3157705493 hasBestOaLocation W31577054931 @default.
• W3157705493 hasConcept C134018914 @default.
• W3157705493 hasConcept C171089720 @default.
• W3157705493 hasConcept C181199279 @default.
• W3157705493 hasConcept C185592680 @default.
• W3157705493 hasConcept C2777165150 @default.
• W3157705493 hasConcept C2779697368 @default.
• W3157705493 hasConcept C2780780548 @default.
• W3157705493 hasConcept C31903555 @default.
• W3157705493 hasConcept C511355011 @default.
• W3157705493 hasConcept C539455810 @default.
• W3157705493 hasConcept C544821477 @default.
• W3157705493 hasConcept C55493867 @default.
• W3157705493 hasConcept C86803240 @default.
• W3157705493 hasConceptScore W3157705493C134018914 @default.
• W3157705493 hasConceptScore W3157705493C171089720 @default.
• W3157705493 hasConceptScore W3157705493C181199279 @default.
• W3157705493 hasConceptScore W3157705493C185592680 @default.
• W3157705493 hasConceptScore W3157705493C2777165150 @default.
• W3157705493 hasConceptScore W3157705493C2779697368 @default.
• W3157705493 hasConceptScore W3157705493C2780780548 @default.
• W3157705493 hasConceptScore W3157705493C31903555 @default.
• W3157705493 hasConceptScore W3157705493C511355011 @default.
• W3157705493 hasConceptScore W3157705493C539455810 @default.
• W3157705493 hasConceptScore W3157705493C544821477 @default.
• W3157705493 hasConceptScore W3157705493C55493867 @default.
• W3157705493 hasConceptScore W3157705493C86803240 @default.
• W3157705493 hasFunder F4320322120 @default.
• W3157705493 hasIssue "1" @default.
• W3157705493 hasLocation W31577054931 @default.

• next