Matches in SemOpenAlex for { <https://semopenalex.org/work/W3157803547> ?p ?o ?g. }
Showing items 1 to 74 of
74
with 100 items per page.
- W3157803547 abstract "Abstract Curcumin-enriched turmeric dietary supplements (DS) are one of the top selling botanicals in the United States. Recent observational studies by our research group have documented turmeric DS use by almost a quarter of breast cancer survivors concurrent with anti-estrogen therapy and a third of those with rheumatoid arthritis. However, some recent reviews have suggested that there is no evidence of any biological effect of curcumin in humans, albeit without rigorous review of published reports. A scoping review of the literature was therefore undertaken to identify clinical trials testing oral curcumin-containing turmeric dietary supplements in humans. Using a defined search strategy, eight databases were reviewed (thru 05/29/2019), identifying 4767 potential English language reports for inclusion, from which all but n = 315 were excluded after review by three independent observers. The majority of studies reported significant effects of turmeric DS on clinical endpoints. Obesity-associated disorders of glucose and lipid metabolism (n =69, including type 2 diabetes mellitus [T2DM], metabolic syndrome and/or hyperlipidemia) or musculoskeletal disorders (n = 46), of which half related to osteoarthritis, were among the most commonly studied diseases in turmeric DS clinical trials, with reported benefits related to inhibition of inflammation, amelioration of hyperlipidemia, increases in adiponectin, and improved glucose control. As is common for botanical clinical trials, the quality of the studies were variable due to lack of clarity about product content as well as study design (e.g. only 60% of T2DM trials and 74% of osteoarthritis trials were randomized, placebo-controlled and double-blinded). However, particularly with respect to treatment of osteoarthritis and metabolic consequences of insulin resistance, the preponderance of the data were suggestive of beneficial physiologic effects. Given the current widespread use of turmeric DS by Americans and existing evidence of possible clinical benefits, further evaluation of turmeric DS efficacy and safety may be warranted." @default.
- W3157803547 created "2021-05-10" @default.
- W3157803547 creator A5024163795 @default.
- W3157803547 creator A5032351878 @default.
- W3157803547 creator A5051357897 @default.
- W3157803547 creator A5071625126 @default.
- W3157803547 creator A5087838202 @default.
- W3157803547 creator A5091117314 @default.
- W3157803547 date "2021-05-01" @default.
- W3157803547 modified "2023-09-23" @default.
- W3157803547 title "Clinical Trials Evaluating Turmeric Dietary Supplement Treatment of Obesity-Associated Disorders of Glucose Metabolism or Bone" @default.
- W3157803547 doi "https://doi.org/10.1210/jendso/bvab048.673" @default.
- W3157803547 hasPublicationYear "2021" @default.
- W3157803547 type Work @default.
- W3157803547 sameAs 3157803547 @default.
- W3157803547 citedByCount "1" @default.
- W3157803547 countsByYear W31578035472021 @default.
- W3157803547 crossrefType "journal-article" @default.
- W3157803547 hasAuthorship W3157803547A5024163795 @default.
- W3157803547 hasAuthorship W3157803547A5032351878 @default.
- W3157803547 hasAuthorship W3157803547A5051357897 @default.
- W3157803547 hasAuthorship W3157803547A5071625126 @default.
- W3157803547 hasAuthorship W3157803547A5087838202 @default.
- W3157803547 hasAuthorship W3157803547A5091117314 @default.
- W3157803547 hasBestOaLocation W31578035471 @default.
- W3157803547 hasConcept C126322002 @default.
- W3157803547 hasConcept C134018914 @default.
- W3157803547 hasConcept C142724271 @default.
- W3157803547 hasConcept C168563851 @default.
- W3157803547 hasConcept C1862650 @default.
- W3157803547 hasConcept C204787440 @default.
- W3157803547 hasConcept C23131810 @default.
- W3157803547 hasConcept C27081682 @default.
- W3157803547 hasConcept C2776164576 @default.
- W3157803547 hasConcept C2777180221 @default.
- W3157803547 hasConcept C2778250585 @default.
- W3157803547 hasConcept C511355011 @default.
- W3157803547 hasConcept C535046627 @default.
- W3157803547 hasConcept C555293320 @default.
- W3157803547 hasConcept C71924100 @default.
- W3157803547 hasConcept C98274493 @default.
- W3157803547 hasConceptScore W3157803547C126322002 @default.
- W3157803547 hasConceptScore W3157803547C134018914 @default.
- W3157803547 hasConceptScore W3157803547C142724271 @default.
- W3157803547 hasConceptScore W3157803547C168563851 @default.
- W3157803547 hasConceptScore W3157803547C1862650 @default.
- W3157803547 hasConceptScore W3157803547C204787440 @default.
- W3157803547 hasConceptScore W3157803547C23131810 @default.
- W3157803547 hasConceptScore W3157803547C27081682 @default.
- W3157803547 hasConceptScore W3157803547C2776164576 @default.
- W3157803547 hasConceptScore W3157803547C2777180221 @default.
- W3157803547 hasConceptScore W3157803547C2778250585 @default.
- W3157803547 hasConceptScore W3157803547C511355011 @default.
- W3157803547 hasConceptScore W3157803547C535046627 @default.
- W3157803547 hasConceptScore W3157803547C555293320 @default.
- W3157803547 hasConceptScore W3157803547C71924100 @default.
- W3157803547 hasConceptScore W3157803547C98274493 @default.
- W3157803547 hasLocation W31578035471 @default.
- W3157803547 hasOpenAccess W3157803547 @default.
- W3157803547 hasPrimaryLocation W31578035471 @default.
- W3157803547 hasRelatedWork W11379314 @default.
- W3157803547 hasRelatedWork W15482908 @default.
- W3157803547 hasRelatedWork W15679389 @default.
- W3157803547 hasRelatedWork W15815898 @default.
- W3157803547 hasRelatedWork W17697861 @default.
- W3157803547 hasRelatedWork W20278449 @default.
- W3157803547 hasRelatedWork W5315526 @default.
- W3157803547 hasRelatedWork W7024069 @default.
- W3157803547 hasRelatedWork W7429388 @default.
- W3157803547 hasRelatedWork W8504805 @default.
- W3157803547 isParatext "false" @default.
- W3157803547 isRetracted "false" @default.
- W3157803547 magId "3157803547" @default.
- W3157803547 workType "article" @default.