Matches in SemOpenAlex for { <https://semopenalex.org/work/W3157804941> ?p ?o ?g. }
- W3157804941 abstract "Recently, nanoparticles have evolved ubiquitously in therapeutic applications to treat a range of diseases. Despite their regular use as therapeutic agents in the clinic, we have yet to see much progress in their clinical translation as diagnostic imaging agents. Several clinical and preclinical studies support their use as imaging contrast agents, but their use in the clinical setting has been limited to off-label imaging procedures (i.e., Feraheme). Since diagnostic imaging has been historically used as an exploratory tool to rule out disease or to screen patients for various cancers, nanoparticle toxicity remains a concern, especially when introducing exogenous contrast agents into a potentially healthy patient population, perhaps rationalizing why several nano-based therapeutic agents have been clinically translated before nano-based imaging agents. Another potential hindrance toward their clinical translation could be their market potential, as most therapeutic drugs have higher earning potential than small-molecule imaging contrast agents. With these considerations in mind, perhaps a clinical path forward for nano-based imaging contrast agents is to help guide/manage therapy. Several studies have demonstrated the ability of nanoparticles to produce more accurate imaging preoperatively, intraoperatively, and postoperatively. These applications illustrate a more reliable method of cancer detection and treatment that can prevent incomplete tumor resection and incorrect assessment of tumor progression following treatment. The aim of this review is to highlight the research that supports the use of nanoparticles in biomedical imaging applications and offer a new perspective to illustrate how nano-based imaging agents have the potential to better inform therapeutic decisions. This article is categorized under: Diagnostic Tools > In Vivo Nanodiagnostics and Imaging." @default.
- W3157804941 created "2021-05-10" @default.
- W3157804941 creator A5063740661 @default.
- W3157804941 creator A5063820570 @default.
- W3157804941 creator A5079656498 @default.
- W3157804941 date "2021-05-02" @default.
- W3157804941 modified "2023-10-16" @default.
- W3157804941 title "A path toward the clinical translation of nano‐based imaging contrast agents" @default.
- W3157804941 cites W1246937494 @default.
- W3157804941 cites W1806770925 @default.
- W3157804941 cites W1965686857 @default.
- W3157804941 cites W1968681772 @default.
- W3157804941 cites W1977871291 @default.
- W3157804941 cites W1983714658 @default.
- W3157804941 cites W1984232298 @default.
- W3157804941 cites W1984906180 @default.
- W3157804941 cites W1987957859 @default.
- W3157804941 cites W1988217845 @default.
- W3157804941 cites W1991842829 @default.
- W3157804941 cites W2002337391 @default.
- W3157804941 cites W2003917401 @default.
- W3157804941 cites W2004381527 @default.
- W3157804941 cites W2007355570 @default.
- W3157804941 cites W2018765716 @default.
- W3157804941 cites W2027137358 @default.
- W3157804941 cites W2060887828 @default.
- W3157804941 cites W2069631908 @default.
- W3157804941 cites W2086171977 @default.
- W3157804941 cites W2089387633 @default.
- W3157804941 cites W2094841478 @default.
- W3157804941 cites W2100426799 @default.
- W3157804941 cites W2102118972 @default.
- W3157804941 cites W2102853861 @default.
- W3157804941 cites W2106739895 @default.
- W3157804941 cites W2109496317 @default.
- W3157804941 cites W2112014411 @default.
- W3157804941 cites W2131150437 @default.
- W3157804941 cites W2148342716 @default.
- W3157804941 cites W2156069838 @default.
- W3157804941 cites W2156729245 @default.
- W3157804941 cites W2160522910 @default.
- W3157804941 cites W2163203871 @default.
- W3157804941 cites W2171158566 @default.
- W3157804941 cites W2187976253 @default.
- W3157804941 cites W2202791313 @default.
- W3157804941 cites W2205710283 @default.
- W3157804941 cites W2222432592 @default.
- W3157804941 cites W2240104466 @default.
- W3157804941 cites W2274832362 @default.
- W3157804941 cites W2303087074 @default.
- W3157804941 cites W2314511842 @default.
- W3157804941 cites W2317019069 @default.
- W3157804941 cites W2317987327 @default.
- W3157804941 cites W2319588997 @default.
- W3157804941 cites W2320866708 @default.
- W3157804941 cites W2329421426 @default.
- W3157804941 cites W2334160756 @default.
- W3157804941 cites W2334394220 @default.
- W3157804941 cites W2340662778 @default.
- W3157804941 cites W2344644350 @default.
- W3157804941 cites W2395607087 @default.
- W3157804941 cites W2409754488 @default.
- W3157804941 cites W2410445673 @default.
- W3157804941 cites W2412955216 @default.
- W3157804941 cites W2416787621 @default.
- W3157804941 cites W2421275313 @default.
- W3157804941 cites W2472308082 @default.
- W3157804941 cites W2531244467 @default.
- W3157804941 cites W2531489761 @default.
- W3157804941 cites W2541390219 @default.
- W3157804941 cites W2561946069 @default.
- W3157804941 cites W2563665409 @default.
- W3157804941 cites W2590661335 @default.
- W3157804941 cites W2591484055 @default.
- W3157804941 cites W2594763087 @default.
- W3157804941 cites W2607015440 @default.
- W3157804941 cites W2609364533 @default.
- W3157804941 cites W2610141571 @default.
- W3157804941 cites W2610542645 @default.
- W3157804941 cites W2626913208 @default.
- W3157804941 cites W2756200663 @default.
- W3157804941 cites W2766366753 @default.
- W3157804941 cites W2767257049 @default.
- W3157804941 cites W2769290845 @default.
- W3157804941 cites W2771830875 @default.
- W3157804941 cites W2784303695 @default.
- W3157804941 cites W2787117586 @default.
- W3157804941 cites W2801884907 @default.
- W3157804941 cites W2802927882 @default.
- W3157804941 cites W2806401188 @default.
- W3157804941 cites W2806547387 @default.
- W3157804941 cites W2806972482 @default.
- W3157804941 cites W2808006305 @default.
- W3157804941 cites W2810420630 @default.
- W3157804941 cites W2883358359 @default.
- W3157804941 cites W2885431777 @default.
- W3157804941 cites W2886585803 @default.
- W3157804941 cites W2887654796 @default.
- W3157804941 cites W2892334869 @default.
- W3157804941 cites W2896212275 @default.