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- W3157883145 endingPage "119891" @default.
- W3157883145 startingPage "119891" @default.
- W3157883145 abstract "As primary industrial raw material, the widespread usage of bisphenol A (BPA) has resulted in sustained release and accumulation in the environment. Besides its endocrine-disrupting character, BPA was reported to generate excessive reactive oxygen species (ROS). However, the potential toxic mechanisms of the BPA-induced oxidative damage to plants were poorly understood. In this study, glutathione peroxidase 6 from Arabidopsis thaliana (AtGPX6) was regarded as biomarker to investigate the toxic effects of BPA on plants by multi-spectroscopic techniques and molecular docking method. Firstly, BPA effectively quenched the intrinsic fluorescence of AtGPX6 via static quenching mechanism, and a single binding site of AtGPX6 towards BPA was presumed. Moreover, the binding force was mainly driven by van der Waals forces and hydrogen bonding based on the negative values of ΔH0 and ΔS0, which was consistent with the molecular docking result. In addition, the conformational changes of AtGPX6 accompanied with the enhancement of the hydrophilicity around the tryptophan residues upon the combination with BPA, were evaluated through the combination of the fluorescence, UV-visible absorption and Circular dichroism (CD) spectroscopy. Finally, the inhibitory impact on the development of Arabidopsis seedling roots was observed under BPA exposure. Therefore, the exploration of the molecular mechanism of AtGPX6 with BPA would provide valuable assessments on the toxic effects of BPA on plants." @default.
- W3157883145 created "2021-05-10" @default.
- W3157883145 creator A5010013507 @default.
- W3157883145 creator A5077987627 @default.
- W3157883145 date "2021-10-01" @default.
- W3157883145 modified "2023-09-26" @default.
- W3157883145 title "Exploring the toxic interactions between Bisphenol A and glutathione peroxidase 6 from Arabidopsis thaliana" @default.
- W3157883145 cites W1964206438 @default.
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- W3157883145 cites W1989046847 @default.
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- W3157883145 cites W2014230319 @default.
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- W3157883145 cites W2024401711 @default.
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- W3157883145 cites W2057486525 @default.
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- W3157883145 cites W2072106080 @default.
- W3157883145 cites W2074601077 @default.
- W3157883145 cites W2082093414 @default.
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- W3157883145 cites W2113763013 @default.
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- W3157883145 doi "https://doi.org/10.1016/j.saa.2021.119891" @default.
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