Matches in SemOpenAlex for { <https://semopenalex.org/work/W3157887238> ?p ?o ?g. }
- W3157887238 abstract "Premotor circuits in the brainstem project to pools of orofacial motoneurons to execute essential motor action such as licking, chewing, breathing, and in rodent, whisking. Previous transsynaptic tracing studies only mapped orofacial premotor circuits in neonatal mice, but the adult circuits remain unknown as a consequence of technical difficulties. Here, we developed a three-step monosynaptic transsynaptic tracing strategy to identify premotor neurons controlling vibrissa, tongue protrusion, and jaw-closing muscles in the adult mouse. We registered these different groups of premotor neurons onto the Allen mouse brain common coordinate framework (CCF) and consequently generated a combined 3D orofacial premotor atlas, revealing unique spatial organizations of distinct premotor circuits. We further uncovered premotor neurons that simultaneously innervate multiple motor nuclei and, consequently, are likely to coordinate different muscles involved in the same orofacial motor actions. Our method for tracing adult premotor circuits and registering to Allen CCF is generally applicable and should facilitate the investigations of motor controls of diverse behaviors." @default.
- W3157887238 created "2021-05-10" @default.
- W3157887238 creator A5003523497 @default.
- W3157887238 creator A5009678650 @default.
- W3157887238 creator A5020283755 @default.
- W3157887238 creator A5022154374 @default.
- W3157887238 creator A5044287913 @default.
- W3157887238 creator A5044984967 @default.
- W3157887238 creator A5050277676 @default.
- W3157887238 creator A5060901954 @default.
- W3157887238 creator A5072325373 @default.
- W3157887238 creator A5077327850 @default.
- W3157887238 date "2021-04-27" @default.
- W3157887238 modified "2023-10-01" @default.
- W3157887238 title "Constructing an adult orofacial premotor atlas in Allen mouse CCF" @default.
- W3157887238 cites W1537795005 @default.
- W3157887238 cites W1555413719 @default.
- W3157887238 cites W1966074450 @default.
- W3157887238 cites W1969324574 @default.
- W3157887238 cites W1970820931 @default.
- W3157887238 cites W1974811041 @default.
- W3157887238 cites W1976560651 @default.
- W3157887238 cites W1981345680 @default.
- W3157887238 cites W1981426699 @default.
- W3157887238 cites W1982506741 @default.
- W3157887238 cites W1991444801 @default.
- W3157887238 cites W2000816595 @default.
- W3157887238 cites W2000856416 @default.
- W3157887238 cites W2006704818 @default.
- W3157887238 cites W2012281924 @default.
- W3157887238 cites W2016378555 @default.
- W3157887238 cites W2018881679 @default.
- W3157887238 cites W2021442546 @default.
- W3157887238 cites W2028254151 @default.
- W3157887238 cites W2030644998 @default.
- W3157887238 cites W2038290671 @default.
- W3157887238 cites W2040713547 @default.
- W3157887238 cites W2040726593 @default.
- W3157887238 cites W2041255690 @default.
- W3157887238 cites W2042437835 @default.
- W3157887238 cites W2050937033 @default.
- W3157887238 cites W2052824828 @default.
- W3157887238 cites W2054454955 @default.
- W3157887238 cites W2054936551 @default.
- W3157887238 cites W2058209319 @default.
- W3157887238 cites W2058253850 @default.
- W3157887238 cites W2063345833 @default.
- W3157887238 cites W2066098296 @default.
- W3157887238 cites W2067401415 @default.
- W3157887238 cites W2074661766 @default.
- W3157887238 cites W2088378833 @default.
- W3157887238 cites W2107905188 @default.
- W3157887238 cites W2117010166 @default.
- W3157887238 cites W2120350910 @default.
- W3157887238 cites W2139681697 @default.
- W3157887238 cites W2141532981 @default.
- W3157887238 cites W2150239645 @default.
- W3157887238 cites W2151361666 @default.
- W3157887238 cites W2164826784 @default.
- W3157887238 cites W2189072864 @default.
- W3157887238 cites W2278395882 @default.
- W3157887238 cites W2319908169 @default.
- W3157887238 cites W2331561558 @default.
- W3157887238 cites W2335967836 @default.
- W3157887238 cites W2398211452 @default.
- W3157887238 cites W2414348333 @default.
- W3157887238 cites W2491847504 @default.
- W3157887238 cites W2527794060 @default.
- W3157887238 cites W2545882160 @default.
- W3157887238 cites W2570025428 @default.
- W3157887238 cites W2588231592 @default.
- W3157887238 cites W2748431171 @default.
- W3157887238 cites W2756746877 @default.
- W3157887238 cites W2792405568 @default.
- W3157887238 cites W2898002359 @default.
- W3157887238 cites W2901313476 @default.
- W3157887238 cites W2952986861 @default.
- W3157887238 cites W2977692735 @default.
- W3157887238 cites W3021105102 @default.
- W3157887238 cites W3138257762 @default.
- W3157887238 cites W4255367522 @default.
- W3157887238 cites W4301498459 @default.
- W3157887238 doi "https://doi.org/10.7554/elife.67291" @default.
- W3157887238 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8137149" @default.
- W3157887238 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33904410" @default.
- W3157887238 hasPublicationYear "2021" @default.
- W3157887238 type Work @default.
- W3157887238 sameAs 3157887238 @default.
- W3157887238 citedByCount "16" @default.
- W3157887238 countsByYear W31578872382021 @default.
- W3157887238 countsByYear W31578872382022 @default.
- W3157887238 countsByYear W31578872382023 @default.
- W3157887238 crossrefType "journal-article" @default.
- W3157887238 hasAuthorship W3157887238A5003523497 @default.
- W3157887238 hasAuthorship W3157887238A5009678650 @default.
- W3157887238 hasAuthorship W3157887238A5020283755 @default.
- W3157887238 hasAuthorship W3157887238A5022154374 @default.
- W3157887238 hasAuthorship W3157887238A5044287913 @default.
- W3157887238 hasAuthorship W3157887238A5044984967 @default.
- W3157887238 hasAuthorship W3157887238A5050277676 @default.