Matches in SemOpenAlex for { <https://semopenalex.org/work/W3157889710> ?p ?o ?g. }
- W3157889710 endingPage "365" @default.
- W3157889710 startingPage "359" @default.
- W3157889710 abstract "The kidney plays a major role to maintain the constancy of the milieu intérieur by adjusting the urinary excretion of water and solutes to the requirement of the body balance. This function is coordinated with elimination of waste products generated among others by the catabolism of proteins and nucleic acids. To cope with these two major functions, the human kidneys generate each day about 180 L of ultrafiltrate from plasma and reabsorbs the vast majority of filtered water and solutes to excrete daily about one-two liter(s) of urine containing concentrations of sodium, potassium and chloride ranging from 20 to 200 mM. The final adjustment of urine composition is finely tuned along the aldosterone-sensitive distal nephron (ASDN) which includes the distal convoluted tubule and the collecting system (connecting tubule and collecting duct). Sodium reabsorption is predominant along the distal tubule if potassium must be spared, or along the collecting system when large amounts of potassium must be secreted. Nephrotic syndrome is characterized by heavy proteinuria consecutive to a glomerular injury, associated with renal sodium and water retention taking initially place along ASDN and leading to edema.Rôle du néphron distal dans le contrôle du volume extracellulaire en condition physiologique et dans le syndrome néphrotique.Les reins jouent un rôle majeur dans le maintien de la composition du milieu intérieur. Cette fonction est coordonnée avec l’élimination des déchets du métabolisme, impliquant la production par les reins d’environ 180 litres de filtrat par jour et la réabsorption de la grande majorité de l’eau et des solutés filtrés. L’ajustement final de la composition de l’urine est réalisé dans le segment distal sensible à l’aldostérone (ASDN), qui inclut le tube contourné distal et le système collecteur. La réabsorption de sodium prédomine dans le tube distal si le potassium doit être épargné, ou dans le système collecteur si le potassium doit être sécrété. Le syndrome néphrotique est caractérisé par une protéinurie massive causée par des lésions glomérulaires, associée à une rétention hydrosodée prenant place dans l’ASDN et induisant chez le patient des œdèmes parfois volumineux." @default.
- W3157889710 created "2021-05-10" @default.
- W3157889710 creator A5011382877 @default.
- W3157889710 creator A5049876191 @default.
- W3157889710 date "2021-04-01" @default.
- W3157889710 modified "2023-09-27" @default.
- W3157889710 title "Rôle du néphron distal dans le contrôle du volume extracellulaire en condition physiologique et dans le syndrome néphrotique" @default.
- W3157889710 cites W154320948 @default.
- W3157889710 cites W1681499960 @default.
- W3157889710 cites W1936780558 @default.
- W3157889710 cites W1970486445 @default.
- W3157889710 cites W1974460588 @default.
- W3157889710 cites W1992847420 @default.
- W3157889710 cites W2017821597 @default.
- W3157889710 cites W2017921001 @default.
- W3157889710 cites W2021360010 @default.
- W3157889710 cites W2026601834 @default.
- W3157889710 cites W2031955017 @default.
- W3157889710 cites W2089627708 @default.
- W3157889710 cites W2097466860 @default.
- W3157889710 cites W2098162793 @default.
- W3157889710 cites W2101068394 @default.
- W3157889710 cites W2104207586 @default.
- W3157889710 cites W2107290783 @default.
- W3157889710 cites W2110858809 @default.
- W3157889710 cites W2117377105 @default.
- W3157889710 cites W2118228561 @default.
- W3157889710 cites W2131947064 @default.
- W3157889710 cites W2135437744 @default.
- W3157889710 cites W2141720478 @default.
- W3157889710 cites W2142214302 @default.
- W3157889710 cites W2154350656 @default.
- W3157889710 cites W2154694043 @default.
- W3157889710 cites W2155165890 @default.
- W3157889710 cites W2166001681 @default.
- W3157889710 cites W2167272727 @default.
- W3157889710 cites W2222653645 @default.
- W3157889710 cites W2303298940 @default.
- W3157889710 cites W2434069888 @default.
- W3157889710 cites W2567518196 @default.
- W3157889710 cites W2709557052 @default.
- W3157889710 cites W2727828904 @default.
- W3157889710 cites W2743817127 @default.
- W3157889710 cites W2962145758 @default.
- W3157889710 cites W2998486416 @default.
- W3157889710 doi "https://doi.org/10.1051/medsci/2021032" @default.
- W3157889710 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33908853" @default.
- W3157889710 hasPublicationYear "2021" @default.
- W3157889710 type Work @default.
- W3157889710 sameAs 3157889710 @default.
- W3157889710 citedByCount "0" @default.
- W3157889710 crossrefType "journal-article" @default.
- W3157889710 hasAuthorship W3157889710A5011382877 @default.
- W3157889710 hasAuthorship W3157889710A5049876191 @default.
- W3157889710 hasBestOaLocation W31578897101 @default.
- W3157889710 hasConcept C126322002 @default.
- W3157889710 hasConcept C134018914 @default.
- W3157889710 hasConcept C153911025 @default.
- W3157889710 hasConcept C159641895 @default.
- W3157889710 hasConcept C178790620 @default.
- W3157889710 hasConcept C185592680 @default.
- W3157889710 hasConcept C2776777027 @default.
- W3157889710 hasConcept C2780091579 @default.
- W3157889710 hasConcept C2781231759 @default.
- W3157889710 hasConcept C3018884230 @default.
- W3157889710 hasConcept C517785266 @default.
- W3157889710 hasConcept C537181965 @default.
- W3157889710 hasConcept C55493867 @default.
- W3157889710 hasConcept C56906281 @default.
- W3157889710 hasConcept C71924100 @default.
- W3157889710 hasConcept C86803240 @default.
- W3157889710 hasConceptScore W3157889710C126322002 @default.
- W3157889710 hasConceptScore W3157889710C134018914 @default.
- W3157889710 hasConceptScore W3157889710C153911025 @default.
- W3157889710 hasConceptScore W3157889710C159641895 @default.
- W3157889710 hasConceptScore W3157889710C178790620 @default.
- W3157889710 hasConceptScore W3157889710C185592680 @default.
- W3157889710 hasConceptScore W3157889710C2776777027 @default.
- W3157889710 hasConceptScore W3157889710C2780091579 @default.
- W3157889710 hasConceptScore W3157889710C2781231759 @default.
- W3157889710 hasConceptScore W3157889710C3018884230 @default.
- W3157889710 hasConceptScore W3157889710C517785266 @default.
- W3157889710 hasConceptScore W3157889710C537181965 @default.
- W3157889710 hasConceptScore W3157889710C55493867 @default.
- W3157889710 hasConceptScore W3157889710C56906281 @default.
- W3157889710 hasConceptScore W3157889710C71924100 @default.
- W3157889710 hasConceptScore W3157889710C86803240 @default.
- W3157889710 hasIssue "4" @default.
- W3157889710 hasLocation W31578897101 @default.
- W3157889710 hasLocation W31578897102 @default.
- W3157889710 hasLocation W31578897103 @default.
- W3157889710 hasLocation W31578897104 @default.
- W3157889710 hasOpenAccess W3157889710 @default.
- W3157889710 hasPrimaryLocation W31578897101 @default.
- W3157889710 hasRelatedWork W1924012380 @default.
- W3157889710 hasRelatedWork W1984193137 @default.
- W3157889710 hasRelatedWork W1984523441 @default.
- W3157889710 hasRelatedWork W2014673722 @default.