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- W3158103614 abstract "Objectives To describe the clinical, histopathologic, and outcomes data for a cohort of patients with biliary atresia (BA), and to identify the factors affecting survival. Methods This was a cross-sectional study of all BA patients diagnosed between 1999 and 2017. Clinical, biochemical, imaging, and histopathologic data were analyzed, and Kaplan–Meier survival rates were compared to identify potential prognostic factors. Results We evaluated 23 patients. The median age at the Kasai procedure was 77 ± 34 days, and the median overall survival was 12.5 ± 65 months. Thirteen (56%) patients survived with their native livers, 3 (13%) received a transplant, and 6 died (26%) while awaiting a transplant. Cholangitis and the use of ursodeoxycholic acid were associated with longer survival, while impaired synthetic function was associated with shorter survival. Conclusions Most patients presented late for the Kasai procedure. The survival rate with the native liver was comparable to other cohorts. Therefore, clinicians are encouraged to refer for the Kasai procedure even with late presentation (between 60 and 90 days), provided there is no hepatic decompensation." @default.
- W3158103614 created "2021-05-10" @default.
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- W3158103614 date "2021-05-01" @default.
- W3158103614 modified "2023-10-01" @default.
- W3158103614 title "Outcomes of late Kasai portoenterostomy in biliary atresia: a single-center experience" @default.
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- W3158103614 doi "https://doi.org/10.1177/03000605211012596" @default.
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