Matches in SemOpenAlex for { <https://semopenalex.org/work/W3158187679> ?p ?o ?g. }
- W3158187679 endingPage "25" @default.
- W3158187679 startingPage "10" @default.
- W3158187679 abstract "In parkinsonian conditions, network dynamics in the cortical and basal ganglia circuits present abnormal oscillations and periods of high synchrony, affecting the functionality of multiple striatal regions including the sensorimotor striatum. However, it is still unclear how these altered dynamics impact on sensory processing, a key feature for motor control that is severely impaired in parkinsonian patients. A major confound is that pathological dynamics in sensorimotor networks may elicit unspecific motor responses that may alter sensory representations through sensory feedback, making it difficult to disentangle motor and sensory components. To address this issue, we studied sensory processing using an anesthetized model with robust sensory representations throughout cortical and basal ganglia sensory regions and limited motor confounds in control and hemiparkinsonian rats. A general screening of sensory-evoked activity in large populations of neurons recorded in the primary sensory cortex (S1), dorsolateral striatum (DLS) and substantia nigra pars reticulata (SNr) revealed increased excitability and altered sensory representations in the three regions. Further analysis revealed uncoordinated population dynamics between DLS and S1/SNr. Finally, DLS lesions in hemiparkinsonian animals partially recovered population dynamics and execution in the rotarod." @default.
- W3158187679 created "2021-05-10" @default.
- W3158187679 creator A5038153864 @default.
- W3158187679 creator A5049562346 @default.
- W3158187679 creator A5052217241 @default.
- W3158187679 creator A5056185797 @default.
- W3158187679 creator A5064922670 @default.
- W3158187679 creator A5067115713 @default.
- W3158187679 creator A5083803592 @default.
- W3158187679 date "2021-07-01" @default.
- W3158187679 modified "2023-10-06" @default.
- W3158187679 title "Altered Sensory Representations in Parkinsonian Cortical and Basal Ganglia Networks" @default.
- W3158187679 cites W14452170 @default.
- W3158187679 cites W1516646705 @default.
- W3158187679 cites W1602611909 @default.
- W3158187679 cites W1912306389 @default.
- W3158187679 cites W1979109520 @default.
- W3158187679 cites W1986961781 @default.
- W3158187679 cites W1988697672 @default.
- W3158187679 cites W1991502776 @default.
- W3158187679 cites W1993179175 @default.
- W3158187679 cites W1993349892 @default.
- W3158187679 cites W2000099578 @default.
- W3158187679 cites W2002016702 @default.
- W3158187679 cites W2005191507 @default.
- W3158187679 cites W2010371447 @default.
- W3158187679 cites W2035725055 @default.
- W3158187679 cites W2036764555 @default.
- W3158187679 cites W2042577989 @default.
- W3158187679 cites W2045379285 @default.
- W3158187679 cites W2048638339 @default.
- W3158187679 cites W2050540607 @default.
- W3158187679 cites W2053210895 @default.
- W3158187679 cites W2054260463 @default.
- W3158187679 cites W2057552598 @default.
- W3158187679 cites W2063215873 @default.
- W3158187679 cites W2074402500 @default.
- W3158187679 cites W2087384202 @default.
- W3158187679 cites W2087565659 @default.
- W3158187679 cites W2087853632 @default.
- W3158187679 cites W2092421775 @default.
- W3158187679 cites W2112337921 @default.
- W3158187679 cites W2120273396 @default.
- W3158187679 cites W2125364686 @default.
- W3158187679 cites W2127149676 @default.
- W3158187679 cites W2133177004 @default.
- W3158187679 cites W2136366217 @default.
- W3158187679 cites W2150135821 @default.
- W3158187679 cites W2150240029 @default.
- W3158187679 cites W2168796299 @default.
- W3158187679 cites W2221686573 @default.
- W3158187679 cites W2472928215 @default.
- W3158187679 cites W2608656574 @default.
- W3158187679 cites W2613689339 @default.
- W3158187679 cites W2614965880 @default.
- W3158187679 cites W2778169119 @default.
- W3158187679 cites W2782306352 @default.
- W3158187679 cites W2899197369 @default.
- W3158187679 cites W2967513791 @default.
- W3158187679 cites W2971944109 @default.
- W3158187679 cites W2980875984 @default.
- W3158187679 cites W3006012411 @default.
- W3158187679 cites W3013063797 @default.
- W3158187679 cites W3030642936 @default.
- W3158187679 cites W3035679764 @default.
- W3158187679 cites W4211044101 @default.
- W3158187679 doi "https://doi.org/10.1016/j.neuroscience.2021.04.031" @default.
- W3158187679 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33965505" @default.
- W3158187679 hasPublicationYear "2021" @default.
- W3158187679 type Work @default.
- W3158187679 sameAs 3158187679 @default.
- W3158187679 citedByCount "6" @default.
- W3158187679 countsByYear W31581876792022 @default.
- W3158187679 countsByYear W31581876792023 @default.
- W3158187679 crossrefType "journal-article" @default.
- W3158187679 hasAuthorship W3158187679A5038153864 @default.
- W3158187679 hasAuthorship W3158187679A5049562346 @default.
- W3158187679 hasAuthorship W3158187679A5052217241 @default.
- W3158187679 hasAuthorship W3158187679A5056185797 @default.
- W3158187679 hasAuthorship W3158187679A5064922670 @default.
- W3158187679 hasAuthorship W3158187679A5067115713 @default.
- W3158187679 hasAuthorship W3158187679A5083803592 @default.
- W3158187679 hasConcept C137183658 @default.
- W3158187679 hasConcept C137813230 @default.
- W3158187679 hasConcept C15744967 @default.
- W3158187679 hasConcept C169760540 @default.
- W3158187679 hasConcept C2776861996 @default.
- W3158187679 hasConcept C2778187257 @default.
- W3158187679 hasConcept C2780062018 @default.
- W3158187679 hasConcept C2780938664 @default.
- W3158187679 hasConcept C2908647359 @default.
- W3158187679 hasConcept C513476851 @default.
- W3158187679 hasConcept C529278444 @default.
- W3158187679 hasConcept C71924100 @default.
- W3158187679 hasConcept C94487597 @default.
- W3158187679 hasConcept C99454951 @default.
- W3158187679 hasConceptScore W3158187679C137183658 @default.
- W3158187679 hasConceptScore W3158187679C137813230 @default.