Matches in SemOpenAlex for { <https://semopenalex.org/work/W3158193485> ?p ?o ?g. }
- W3158193485 endingPage "136" @default.
- W3158193485 startingPage "125" @default.
- W3158193485 abstract "Fibromyalgia is a prevalent pain condition that is associated with cognitive impairments including in attention, memory, and executive processing. It has been proposed that fibromyalgia may be caused by altered central pain processing characterised by a loss of endogenous pain modulation. We tested whether attentional analgesia, where cognitive engagement diminishes pain percept, was attenuated in patients with fibromyalgia (n = 20) compared with matched healthy controls (n = 20). An individually calibrated, attentional analgesia paradigm with a 2 × 2 factorial design was used with brain and brainstem-focussed functional magnetic resonance imaging. Patients with fibromyalgia had both lower heat pain thresholds and speeds in a visual attention task. When this was taken into account for both attentional task and thermal stimulation, both groups exhibited an equivalent degree of attentional analgesia. Functional magnetic resonance imaging analysis showed similar patterns of activation in the main effects of pain and attention in the brain and brainstem (with the sole exceptions of increased activation in the control group in the frontopolar cortex and the ipsilateral locus coeruleus). The attentional analgesic effect correlated with activity in the periaqueductal gray and rostral ventromedial medulla. These findings indicate that patients with fibromyalgia can engage the descending pain modulatory system if the attentional task and noxious stimulus intensity are appropriately titrated." @default.
- W3158193485 created "2021-05-10" @default.
- W3158193485 creator A5020357995 @default.
- W3158193485 creator A5039963493 @default.
- W3158193485 creator A5071615877 @default.
- W3158193485 creator A5081264422 @default.
- W3158193485 date "2021-05-01" @default.
- W3158193485 modified "2023-10-12" @default.
- W3158193485 title "Central pain modulatory mechanisms of attentional analgesia are preserved in fibromyalgia" @default.
- W3158193485 cites W1567257801 @default.
- W3158193485 cites W1777948354 @default.
- W3158193485 cites W1967791807 @default.
- W3158193485 cites W1967999836 @default.
- W3158193485 cites W1968654102 @default.
- W3158193485 cites W1976288643 @default.
- W3158193485 cites W1976846134 @default.
- W3158193485 cites W1978660262 @default.
- W3158193485 cites W1981291046 @default.
- W3158193485 cites W1983249684 @default.
- W3158193485 cites W1989247930 @default.
- W3158193485 cites W1989384554 @default.
- W3158193485 cites W1990590339 @default.
- W3158193485 cites W1993646988 @default.
- W3158193485 cites W1993852907 @default.
- W3158193485 cites W1994463719 @default.
- W3158193485 cites W2003083222 @default.
- W3158193485 cites W2009318374 @default.
- W3158193485 cites W2016587519 @default.
- W3158193485 cites W2016839655 @default.
- W3158193485 cites W2020744229 @default.
- W3158193485 cites W2021042430 @default.
- W3158193485 cites W2023995612 @default.
- W3158193485 cites W2033577846 @default.
- W3158193485 cites W2041683329 @default.
- W3158193485 cites W2043149073 @default.
- W3158193485 cites W2043172641 @default.
- W3158193485 cites W2049056319 @default.
- W3158193485 cites W2054835904 @default.
- W3158193485 cites W2056196470 @default.
- W3158193485 cites W2059492864 @default.
- W3158193485 cites W2059634785 @default.
- W3158193485 cites W2059810347 @default.
- W3158193485 cites W2062700118 @default.
- W3158193485 cites W2063033846 @default.
- W3158193485 cites W2072129911 @default.
- W3158193485 cites W2075676781 @default.
- W3158193485 cites W2079166986 @default.
- W3158193485 cites W2087005128 @default.
- W3158193485 cites W2091211206 @default.
- W3158193485 cites W2095511769 @default.
- W3158193485 cites W2102165127 @default.
- W3158193485 cites W2107444050 @default.
- W3158193485 cites W2108197576 @default.
- W3158193485 cites W2111293376 @default.
- W3158193485 cites W2119376431 @default.
- W3158193485 cites W2125635982 @default.
- W3158193485 cites W2128243813 @default.
- W3158193485 cites W2129436894 @default.
- W3158193485 cites W2134305330 @default.
- W3158193485 cites W2136022845 @default.
- W3158193485 cites W2138790588 @default.
- W3158193485 cites W2148726987 @default.
- W3158193485 cites W2151651036 @default.
- W3158193485 cites W2154693681 @default.
- W3158193485 cites W2160820922 @default.
- W3158193485 cites W2166151683 @default.
- W3158193485 cites W2166281097 @default.
- W3158193485 cites W2253364553 @default.
- W3158193485 cites W2276834474 @default.
- W3158193485 cites W2339767472 @default.
- W3158193485 cites W2395203281 @default.
- W3158193485 cites W2513715080 @default.
- W3158193485 cites W2527183389 @default.
- W3158193485 cites W2561584446 @default.
- W3158193485 cites W2576854225 @default.
- W3158193485 cites W2592931040 @default.
- W3158193485 cites W2612313402 @default.
- W3158193485 cites W2772182066 @default.
- W3158193485 cites W2790178437 @default.
- W3158193485 cites W2793285114 @default.
- W3158193485 cites W2888150073 @default.
- W3158193485 cites W2910499539 @default.
- W3158193485 cites W2937730583 @default.
- W3158193485 cites W2960981045 @default.
- W3158193485 cites W2977883299 @default.
- W3158193485 cites W2982415033 @default.
- W3158193485 cites W2987283905 @default.
- W3158193485 cites W2989783043 @default.
- W3158193485 cites W2991446230 @default.
- W3158193485 cites W3085448556 @default.
- W3158193485 cites W3099030518 @default.
- W3158193485 cites W4235770099 @default.
- W3158193485 doi "https://doi.org/10.1097/j.pain.0000000000002319" @default.
- W3158193485 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33941755" @default.
- W3158193485 hasPublicationYear "2021" @default.
- W3158193485 type Work @default.
- W3158193485 sameAs 3158193485 @default.
- W3158193485 citedByCount "7" @default.