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• W3158278598 abstract "Diet plays an essential role in human development and growth, contributing to health and well-being. The socio-economic values, cultural perspectives, and dietary formulation in sub-Saharan Africa can influence gut health and disease prevention. The vast microbial ecosystems in the human gut frequently interrelate to maintain a healthy, well-coordinated cellular and humoral immune signalling to prevent metabolic dysfunction, pathogen dominance, and induction of systemic diseases. The diverse indigenous diets could differentially act as biotherapeutics to modulate microbial abundance and population characteristics. Such modulation could prevent stunted growth, malnutrition, induction of bowel diseases, attenuated immune responses, and mortality, particularly among infants. Understanding the associations between specific indigenous African diets and the predictability of the dynamics of gut bacteria genera promises potential biotherapeutics towards improving the prevention, control, and treatment of microbiome-associated diseases such as cancer, inflammatory bowel disease, obesity, type 2 diabetes, and cardiovascular disease. The dietary influence of many African diets (especially grain-base such as millet, maize, brown rice, sorghum, soya, and tapioca) promotes gut lining integrity, immune tolerance towards the microbiota, and its associated immune and inflammatory responses. A fibre-rich diet is a promising biotherapeutic candidate that could effectively modulate inflammatory mediators’ expression associated with immune cell migration, lymphoid tissue maturation, and signalling pathways. It could also modulate the stimulation of cytokines and chemokines involved in ensuring balance for long-term microbiome programming. The interplay between host and gut microbial digestion is complex; microbes using and competing for dietary and endogenous proteins are often attributable to variances in the comparative abundances of Enterobacteriaceae taxa. Many auto-inducers could initiate the process of quorum sensing and mammalian epinephrine host cell signalling system. It could also downregulate inflammatory signals with microbiota tumour taxa that could trigger colorectal cancer initiation, metabolic type 2 diabetes, and inflammatory bowel diseases. The exploitation of essential biotherapeutic molecules derived from fibre-rich indigenous diet promises food substances for the downregulation of inflammatory signalling that could be harmful to gut microbiota ecological balance and improved immune response modulation." @default.
• W3158278598 created "2021-05-10" @default.
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• W3158278598 date "2021-01-01" @default.
• W3158278598 modified "2023-10-01" @default.
• W3158278598 title "Significance of African Diets in Biotherapeutic Modulation of the Gut Microbiome" @default.
• W3158278598 cites W2560758606 @default.
• W3158278598 cites W2587135005 @default.
• W3158278598 cites W2593928562 @default.
• W3158278598 cites W2604323123 @default.
• W3158278598 cites W2611502608 @default.
• W3158278598 cites W2616825195 @default.
• W3158278598 cites W2620068414 @default.
• W3158278598 cites W2620098478 @default.
• W3158278598 cites W2620344213 @default.
• W3158278598 cites W2625207619 @default.
• W3158278598 cites W2734632372 @default.
• W3158278598 cites W2737314812 @default.
• W3158278598 cites W2737465877 @default.
• W3158278598 cites W2738534526 @default.
• W3158278598 cites W2744495024 @default.
• W3158278598 cites W2748872697 @default.
• W3158278598 cites W2749822530 @default.
• W3158278598 cites W2751128104 @default.
• W3158278598 cites W2751467691 @default.
• W3158278598 cites W2757559153 @default.
• W3158278598 cites W2762334278 @default.
• W3158278598 cites W2766511122 @default.
• W3158278598 cites W2767512583 @default.
• W3158278598 cites W2787472812 @default.
• W3158278598 cites W2787902098 @default.
• W3158278598 cites W2788730359 @default.
• W3158278598 cites W2789006532 @default.
• W3158278598 cites W2790478543 @default.
• W3158278598 cites W2792385423 @default.
• W3158278598 cites W2792808282 @default.
• W3158278598 cites W2797443945 @default.
• W3158278598 cites W2801162844 @default.
• W3158278598 cites W2846061873 @default.
• W3158278598 cites W2883244959 @default.
• W3158278598 cites W2884935659 @default.
• W3158278598 cites W2885836988 @default.
• W3158278598 cites W2886248824 @default.
• W3158278598 cites W2889822028 @default.
• W3158278598 cites W2891128176 @default.
• W3158278598 cites W2891740518 @default.
• W3158278598 cites W2894120184 @default.
• W3158278598 cites W2895153150 @default.
• W3158278598 cites W2899852374 @default.
• W3158278598 cites W2900205080 @default.
• W3158278598 cites W2901283764 @default.
• W3158278598 cites W2901557220 @default.
• W3158278598 cites W2908597227 @default.
• W3158278598 cites W2908921604 @default.
• W3158278598 cites W2909668868 @default.
• W3158278598 cites W2910073785 @default.
• W3158278598 cites W2912227533 @default.
• W3158278598 cites W2912242406 @default.
• W3158278598 cites W2912324309 @default.
• W3158278598 cites W2913315260 @default.
• W3158278598 cites W2913641200 @default.
• W3158278598 cites W2919346978 @default.
• W3158278598 cites W2921970308 @default.
• W3158278598 cites W2923466480 @default.
• W3158278598 cites W2924880215 @default.
• W3158278598 cites W2928730464 @default.
• W3158278598 cites W2931011504 @default.
• W3158278598 cites W2935676311 @default.
• W3158278598 cites W2938918172 @default.
• W3158278598 cites W2942098219 @default.
• W3158278598 cites W2942185461 @default.
• W3158278598 cites W2946001492 @default.
• W3158278598 cites W2946719617 @default.

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