Matches in SemOpenAlex for { <https://semopenalex.org/work/W3158367166> ?p ?o ?g. }
- W3158367166 endingPage "2703" @default.
- W3158367166 startingPage "2703" @default.
- W3158367166 abstract "Recent findings suggest that tumor microenvironment (TME) plays an important regulatory role in the occurrence, proliferation, and metastasis of tumors. Different from normal tissue, the condition around tumor significantly altered, including immune infiltration, compact extracellular matrix, new vasculatures, abundant enzyme, acidic pH value, and hypoxia. Increasingly, researchers focused on targeting TME to prevent tumor development and metastasis. With the development of nanotechnology and the deep research on the tumor environment, stimulation-responsive intelligent nanostructures designed based on TME have attracted much attention in the anti-tumor drug delivery system. TME-targeted nano therapeutics can regulate the distribution of drugs in the body, specifically increase the concentration of drugs in the tumor site, so as to enhance the efficacy and reduce adverse reactions, can utilize particular conditions of TME to improve the effect of tumor therapy. This paper summarizes the major components and characteristics of TME, discusses the principles and strategies of relevant nano-architectures targeting TME for the treatment and diagnosis systematically." @default.
- W3158367166 created "2021-05-10" @default.
- W3158367166 creator A5004318102 @default.
- W3158367166 creator A5024025794 @default.
- W3158367166 creator A5026930533 @default.
- W3158367166 creator A5056919239 @default.
- W3158367166 date "2021-05-05" @default.
- W3158367166 modified "2023-10-13" @default.
- W3158367166 title "Exploiting a New Approach to Destroy the Barrier of Tumor Microenvironment: Nano-Architecture Delivery Systems" @default.
- W3158367166 cites W1970825260 @default.
- W3158367166 cites W1986321004 @default.
- W3158367166 cites W1987534017 @default.
- W3158367166 cites W1991032925 @default.
- W3158367166 cites W1998664010 @default.
- W3158367166 cites W1999033990 @default.
- W3158367166 cites W2012076116 @default.
- W3158367166 cites W2026807600 @default.
- W3158367166 cites W2028544780 @default.
- W3158367166 cites W2050417053 @default.
- W3158367166 cites W2058559717 @default.
- W3158367166 cites W2074939270 @default.
- W3158367166 cites W2076189832 @default.
- W3158367166 cites W2085148527 @default.
- W3158367166 cites W2087625780 @default.
- W3158367166 cites W2088659772 @default.
- W3158367166 cites W2111762872 @default.
- W3158367166 cites W2114248398 @default.
- W3158367166 cites W2132732108 @default.
- W3158367166 cites W2142755954 @default.
- W3158367166 cites W2143839116 @default.
- W3158367166 cites W2148801612 @default.
- W3158367166 cites W2153960708 @default.
- W3158367166 cites W2167064954 @default.
- W3158367166 cites W2169465106 @default.
- W3158367166 cites W2178164343 @default.
- W3158367166 cites W2266683146 @default.
- W3158367166 cites W2271254242 @default.
- W3158367166 cites W2279217276 @default.
- W3158367166 cites W2288119981 @default.
- W3158367166 cites W2295358293 @default.
- W3158367166 cites W2300452871 @default.
- W3158367166 cites W2314930919 @default.
- W3158367166 cites W2322861634 @default.
- W3158367166 cites W2324117139 @default.
- W3158367166 cites W2326188833 @default.
- W3158367166 cites W2463788395 @default.
- W3158367166 cites W2510079342 @default.
- W3158367166 cites W2512421994 @default.
- W3158367166 cites W2512899508 @default.
- W3158367166 cites W2514227379 @default.
- W3158367166 cites W2526296188 @default.
- W3158367166 cites W2530020056 @default.
- W3158367166 cites W2532525412 @default.
- W3158367166 cites W2541390219 @default.
- W3158367166 cites W2550267433 @default.
- W3158367166 cites W2595863515 @default.
- W3158367166 cites W2597510857 @default.
- W3158367166 cites W2602388159 @default.
- W3158367166 cites W2604354601 @default.
- W3158367166 cites W2607137647 @default.
- W3158367166 cites W2613176174 @default.
- W3158367166 cites W2615301036 @default.
- W3158367166 cites W2688837414 @default.
- W3158367166 cites W2729471090 @default.
- W3158367166 cites W2738239402 @default.
- W3158367166 cites W2740495409 @default.
- W3158367166 cites W2742532112 @default.
- W3158367166 cites W2743361508 @default.
- W3158367166 cites W2746888048 @default.
- W3158367166 cites W2748037493 @default.
- W3158367166 cites W2753847978 @default.
- W3158367166 cites W2755181857 @default.
- W3158367166 cites W2762280203 @default.
- W3158367166 cites W2763984870 @default.
- W3158367166 cites W2765779358 @default.
- W3158367166 cites W2766272075 @default.
- W3158367166 cites W2769869838 @default.
- W3158367166 cites W2771018339 @default.
- W3158367166 cites W2773427199 @default.
- W3158367166 cites W2775666728 @default.
- W3158367166 cites W2777459838 @default.
- W3158367166 cites W2781494443 @default.
- W3158367166 cites W2783483481 @default.
- W3158367166 cites W2783703728 @default.
- W3158367166 cites W2784549607 @default.
- W3158367166 cites W2785803176 @default.
- W3158367166 cites W2786987313 @default.
- W3158367166 cites W2786992500 @default.
- W3158367166 cites W2791575850 @default.
- W3158367166 cites W2791741430 @default.
- W3158367166 cites W2791796087 @default.
- W3158367166 cites W2792603848 @default.
- W3158367166 cites W2794201416 @default.
- W3158367166 cites W2797429263 @default.
- W3158367166 cites W2797866384 @default.
- W3158367166 cites W2800380311 @default.
- W3158367166 cites W2800477374 @default.
- W3158367166 cites W2801177534 @default.