FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3158518151> ?p ?o ?g. }

• W3158518151 endingPage "3492" @default.
• W3158518151 startingPage "3482" @default.
• W3158518151 abstract "Surgery is the predominant treatment modality of human glioma but suffers difficulty on clearly identifying tumor boundaries in clinic. Conventional practice involves neurosurgeon's visual evaluation and intraoperative histological examination of dissected tissues using frozen section, which is time-consuming and complex. The aim of this study was to develop fluorescent imaging coupled with artificial intelligence technique to quickly and accurately determine glioma in real-time during surgery.Glioma patients (N = 23) were enrolled and injected with indocyanine green for fluorescence image-guided surgery. Tissue samples (N = 1874) were harvested from surgery of these patients, and the second near-infrared window (NIR-II, 1000-1700 nm) fluorescence images were obtained. Deep convolutional neural networks (CNNs) combined with NIR-II fluorescence imaging (named as FL-CNN) were explored to automatically provide pathological diagnosis of glioma in situ in real-time during patient surgery. The pathological examination results were used as the gold standard.The developed FL-CNN achieved the area under the curve (AUC) of 0.945. Comparing to neurosurgeons' judgment, with the same level of specificity >80%, FL-CNN achieved a much higher sensitivity (93.8% versus 82.0%, P < 0.001) with zero time overhead. Further experiments demonstrated that FL-CNN corrected >70% of the errors made by neurosurgeons. FL-CNN was also able to rapidly predict grade and Ki-67 level (AUC 0.810 and 0.625) of tumor specimens intraoperatively.Our study demonstrates that deep CNNs are better at capturing important information from fluorescence images than surgeons' evaluation during patient surgery. FL-CNN is highly promising to provide pathological diagnosis intraoperatively and assist neurosurgeons to obtain maximum resection safely.ChiCTR ChiCTR2000029402. Registered 29 January 2020, retrospectively registered." @default.
• W3158518151 created "2021-05-10" @default.
• W3158518151 creator A5015676600 @default.
• W3158518151 creator A5019959232 @default.
• W3158518151 creator A5025768990 @default.
• W3158518151 creator A5061361518 @default.
• W3158518151 creator A5062435881 @default.
• W3158518151 creator A5077558876 @default.
• W3158518151 creator A5079494298 @default.
• W3158518151 creator A5082115447 @default.
• W3158518151 date "2021-04-27" @default.
• W3158518151 modified "2023-10-18" @default.
• W3158518151 title "Real-time intraoperative glioma diagnosis using fluorescence imaging and deep convolutional neural networks" @default.
• W3158518151 cites W1554441203 @default.
• W3158518151 cites W1996727406 @default.
• W3158518151 cites W2006617902 @default.
• W3158518151 cites W2011301426 @default.
• W3158518151 cites W2065646079 @default.
• W3158518151 cites W2148977460 @default.
• W3158518151 cites W2345877254 @default.
• W3158518151 cites W2523582041 @default.
• W3158518151 cites W2530071270 @default.
• W3158518151 cites W2574563551 @default.
• W3158518151 cites W2586457244 @default.
• W3158518151 cites W2734369741 @default.
• W3158518151 cites W2760946358 @default.
• W3158518151 cites W2761668583 @default.
• W3158518151 cites W2765636566 @default.
• W3158518151 cites W2811121616 @default.
• W3158518151 cites W2884741638 @default.
• W3158518151 cites W2900530921 @default.
• W3158518151 cites W2902644322 @default.
• W3158518151 cites W2905307056 @default.
• W3158518151 cites W2913160101 @default.
• W3158518151 cites W2947810057 @default.
• W3158518151 cites W2948930564 @default.
• W3158518151 cites W2949289995 @default.
• W3158518151 cites W2956228567 @default.
• W3158518151 cites W2995471545 @default.
• W3158518151 cites W2998401461 @default.
• W3158518151 cites W3017170546 @default.
• W3158518151 cites W4230172521 @default.
• W3158518151 doi "https://doi.org/10.1007/s00259-021-05326-y" @default.
• W3158518151 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8440289" @default.
• W3158518151 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33904984" @default.
• W3158518151 hasPublicationYear "2021" @default.
• W3158518151 type Work @default.
• W3158518151 sameAs 3158518151 @default.
• W3158518151 citedByCount "16" @default.
• W3158518151 countsByYear W31585181512022 @default.
• W3158518151 countsByYear W31585181512023 @default.
• W3158518151 crossrefType "journal-article" @default.
• W3158518151 hasAuthorship W3158518151A5015676600 @default.
• W3158518151 hasAuthorship W3158518151A5019959232 @default.
• W3158518151 hasAuthorship W3158518151A5025768990 @default.
• W3158518151 hasAuthorship W3158518151A5061361518 @default.
• W3158518151 hasAuthorship W3158518151A5062435881 @default.
• W3158518151 hasAuthorship W3158518151A5077558876 @default.
• W3158518151 hasAuthorship W3158518151A5079494298 @default.
• W3158518151 hasAuthorship W3158518151A5082115447 @default.
• W3158518151 hasBestOaLocation W31585181511 @default.
• W3158518151 hasConcept C121332964 @default.
• W3158518151 hasConcept C126838900 @default.
• W3158518151 hasConcept C12770488 @default.
• W3158518151 hasConcept C141071460 @default.
• W3158518151 hasConcept C154945302 @default.
• W3158518151 hasConcept C2778227246 @default.
• W3158518151 hasConcept C2781065829 @default.
• W3158518151 hasConcept C2989005 @default.
• W3158518151 hasConcept C40993552 @default.
• W3158518151 hasConcept C41008148 @default.
• W3158518151 hasConcept C502942594 @default.
• W3158518151 hasConcept C57477423 @default.
• W3158518151 hasConcept C62520636 @default.
• W3158518151 hasConcept C71924100 @default.
• W3158518151 hasConcept C81363708 @default.
• W3158518151 hasConcept C91881484 @default.
• W3158518151 hasConceptScore W3158518151C121332964 @default.
• W3158518151 hasConceptScore W3158518151C126838900 @default.
• W3158518151 hasConceptScore W3158518151C12770488 @default.
• W3158518151 hasConceptScore W3158518151C141071460 @default.
• W3158518151 hasConceptScore W3158518151C154945302 @default.
• W3158518151 hasConceptScore W3158518151C2778227246 @default.
• W3158518151 hasConceptScore W3158518151C2781065829 @default.
• W3158518151 hasConceptScore W3158518151C2989005 @default.
• W3158518151 hasConceptScore W3158518151C40993552 @default.
• W3158518151 hasConceptScore W3158518151C41008148 @default.
• W3158518151 hasConceptScore W3158518151C502942594 @default.
• W3158518151 hasConceptScore W3158518151C57477423 @default.
• W3158518151 hasConceptScore W3158518151C62520636 @default.
• W3158518151 hasConceptScore W3158518151C71924100 @default.
• W3158518151 hasConceptScore W3158518151C81363708 @default.
• W3158518151 hasConceptScore W3158518151C91881484 @default.
• W3158518151 hasFunder F4320321001 @default.
• W3158518151 hasFunder F4320321133 @default.
• W3158518151 hasFunder F4320322919 @default.
• W3158518151 hasFunder F4320334978 @default.
• W3158518151 hasIssue "11" @default.

• next