FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3158524897> ?p ?o ?g. }

• W3158524897 abstract "Abstract Myofibres (primary and secondary myofibre) are the basic structure of muscle and the determinant of muscle mass. To explore the skeletal muscle developmental processes from primary myofibres to secondary myofibres in pigs, we conducted an integrative three-dimensional structure of genome and transcriptomic characterization of longissimus dorsi muscle of pig from primary myofibre formation stage [embryonic Day 35 (E35)] to secondary myofibre formation stage (E80). In the hierarchical genomic structure, we found that 11.43% of genome switched compartment A/B status, 14.53% of topologically associating domains are changed intradomain interactions (D-scores) and 2,730 genes with differential promoter–enhancer interactions and (or) enhancer activity from E35 to E80. The alterations of genome architecture were found to correlate with expression of genes that play significant roles in neuromuscular junction, embryonic morphogenesis, skeletal muscle development or metabolism, typically, NEFL, MuSK, SLN, Mef2D and GCK. Significantly, Sox6 and MATN2 play important roles in the process of primary to secondary myofibres formation and increase the regulatory potential score and genes expression in it. In brief, we reveal the genomic reorganization from E35 to E80 and construct genome-wide high-resolution interaction maps that provide a resource for studying long-range control of gene expression from E35 to E80." @default.
• W3158524897 created "2021-05-10" @default.
• W3158524897 creator A5003029704 @default.
• W3158524897 creator A5006444579 @default.
• W3158524897 creator A5013969818 @default.
• W3158524897 creator A5018451568 @default.
• W3158524897 creator A5024440200 @default.
• W3158524897 creator A5030260621 @default.
• W3158524897 creator A5034686488 @default.
• W3158524897 creator A5037389219 @default.
• W3158524897 creator A5043089066 @default.
• W3158524897 creator A5050206847 @default.
• W3158524897 creator A5057513521 @default.
• W3158524897 creator A5076199866 @default.
• W3158524897 creator A5085813632 @default.
• W3158524897 date "2021-04-01" @default.
• W3158524897 modified "2023-10-17" @default.
• W3158524897 title "Reorganization of chromatin architecture during prenatal development of porcine skeletal muscle" @default.
• W3158524897 cites W1483613642 @default.
• W3158524897 cites W1534052749 @default.
• W3158524897 cites W1540326034 @default.
• W3158524897 cites W1550872113 @default.
• W3158524897 cites W1573544812 @default.
• W3158524897 cites W1594056720 @default.
• W3158524897 cites W1605145036 @default.
• W3158524897 cites W1967387547 @default.
• W3158524897 cites W1973062929 @default.
• W3158524897 cites W1989431246 @default.
• W3158524897 cites W1992036272 @default.
• W3158524897 cites W1999600588 @default.
• W3158524897 cites W2000287799 @default.
• W3158524897 cites W2005110451 @default.
• W3158524897 cites W2006547120 @default.
• W3158524897 cites W2007070249 @default.
• W3158524897 cites W2022179732 @default.
• W3158524897 cites W2027745468 @default.
• W3158524897 cites W2030294830 @default.
• W3158524897 cites W2035012119 @default.
• W3158524897 cites W2039309132 @default.
• W3158524897 cites W2039763138 @default.
• W3158524897 cites W2045528664 @default.
• W3158524897 cites W2048898838 @default.
• W3158524897 cites W2054919793 @default.
• W3158524897 cites W2057313033 @default.
• W3158524897 cites W2059048039 @default.
• W3158524897 cites W2059216629 @default.
• W3158524897 cites W2065656177 @default.
• W3158524897 cites W2069989784 @default.
• W3158524897 cites W2070021921 @default.
• W3158524897 cites W2071800537 @default.
• W3158524897 cites W2075734430 @default.
• W3158524897 cites W2079530305 @default.
• W3158524897 cites W2080477348 @default.
• W3158524897 cites W2082442359 @default.
• W3158524897 cites W2087386268 @default.
• W3158524897 cites W2094608127 @default.
• W3158524897 cites W2095009817 @default.
• W3158524897 cites W2102130285 @default.
• W3158524897 cites W2110234305 @default.
• W3158524897 cites W2125037856 @default.
• W3158524897 cites W2125391492 @default.
• W3158524897 cites W2143061420 @default.
• W3158524897 cites W2148646540 @default.
• W3158524897 cites W2152791321 @default.
• W3158524897 cites W2163361011 @default.
• W3158524897 cites W2163412235 @default.
• W3158524897 cites W2165869751 @default.
• W3158524897 cites W2294365510 @default.
• W3158524897 cites W2324904309 @default.
• W3158524897 cites W2346705222 @default.
• W3158524897 cites W2410489113 @default.
• W3158524897 cites W2411398599 @default.
• W3158524897 cites W2520543091 @default.
• W3158524897 cites W2557223986 @default.
• W3158524897 cites W2565257179 @default.
• W3158524897 cites W2604445208 @default.
• W3158524897 cites W2606835133 @default.
• W3158524897 cites W2620165518 @default.
• W3158524897 cites W2625231465 @default.
• W3158524897 cites W2734870846 @default.
• W3158524897 cites W2735035409 @default.
• W3158524897 cites W2745773403 @default.
• W3158524897 cites W2745967441 @default.
• W3158524897 cites W2769276755 @default.
• W3158524897 cites W2786174959 @default.
• W3158524897 cites W2806394352 @default.
• W3158524897 cites W2891343443 @default.
• W3158524897 cites W2909044048 @default.
• W3158524897 cites W2913432075 @default.
• W3158524897 cites W2915314018 @default.
• W3158524897 cites W2922635103 @default.
• W3158524897 cites W2928665623 @default.
• W3158524897 cites W2937408164 @default.
• W3158524897 cites W2952203741 @default.
• W3158524897 cites W2953369069 @default.
• W3158524897 cites W2961201600 @default.
• W3158524897 cites W3007611504 @default.
• W3158524897 cites W3011952272 @default.
• W3158524897 doi "https://doi.org/10.1093/dnares/dsab003" @default.
• W3158524897 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8154859" @default.

• next