FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3158538823> ?p ?o ?g. }

• W3158538823 endingPage "2295" @default.
• W3158538823 startingPage "2291" @default.
• W3158538823 abstract "Background: The aim of this review is to compare the efficacy of liraglutide versus sitagliptin add-on-to metformin in patients with Type 2 Diabetes Mellitus and inadequate glycemic control for rational use of drugs. Methods: We searched for randomized controlled trials (RCT) in MEDLINE, Web of science, PubMed, Cochrane library, CNKI, and Wanfang database and extracted data from all randomized controlled trials (RCTs) up to July 11, 2019 of liraglutide versus sitagliptin given in combination with metformin. RCTs were selected only if they were RCTs comparing DPP-4 inhibitor (sitagliptin) monotherapy to metformin monotherapy with the GLP-1 Receptor Agonists (liraglutide), duration of treatment was ≥26 weeks and reported data on hemoglobin A1c (HbA1c) change, fasting plasma glucose (FPG) change, Odds ratio (OR), mean difference (MD), 95% confidence interval are used to analyze the outcomes. Results: A total of 2,257 patients from 6 RCTs were included in the study. When compared with sitagliptin (100mg) in combination with metformin group, the group of patients treated with liraglutide1.2mg and 1.8mg and metformin, produced greater reduction in HbA1c, FBG. (95% CI). The group of patients with 1.8mg liraglutide had significant weight loss. The incidence of nausea, hypoglycemic episodes, gastrointestinal problems was higher than the sitagliptin with metformin groups. Conclusions: The results of this study indicated that the liraglutide – metformin combination therapy could significantly lower the HbA1c level and increased reduction of body weight. ADRs such as gastrointestinal problems, hypoglycemic episodes were common in liraglutide treatment group." @default.
• W3158538823 created "2021-05-10" @default.
• W3158538823 creator A5000566569 @default.
• W3158538823 creator A5064384282 @default.
• W3158538823 creator A5065936802 @default.
• W3158538823 date "2021-04-29" @default.
• W3158538823 modified "2023-09-23" @default.
• W3158538823 title "A Review: Comparison of Efficacy of Liraglutide Versus Sitagliptin add-on-to Metformin in Type 2 Diabetes Mellitus patients" @default.
• W3158538823 cites W1969151129 @default.
• W3158538823 cites W1990028696 @default.
• W3158538823 cites W2006945811 @default.
• W3158538823 cites W2013851956 @default.
• W3158538823 cites W2018192866 @default.
• W3158538823 cites W2050851282 @default.
• W3158538823 cites W2058197822 @default.
• W3158538823 cites W2098923148 @default.
• W3158538823 cites W2107572009 @default.
• W3158538823 cites W2113367996 @default.
• W3158538823 cites W2119008227 @default.
• W3158538823 cites W2127018329 @default.
• W3158538823 cites W2145669212 @default.
• W3158538823 cites W2170606300 @default.
• W3158538823 cites W2236659707 @default.
• W3158538823 cites W2264809036 @default.
• W3158538823 cites W2287471961 @default.
• W3158538823 cites W2328107407 @default.
• W3158538823 cites W2341996933 @default.
• W3158538823 cites W2511454140 @default.
• W3158538823 cites W2563047690 @default.
• W3158538823 cites W2679991926 @default.
• W3158538823 cites W2756548008 @default.
• W3158538823 cites W2761185561 @default.
• W3158538823 cites W3006987728 @default.
• W3158538823 cites W3007047702 @default.
• W3158538823 cites W3008193796 @default.
• W3158538823 cites W3015647217 @default.
• W3158538823 doi "https://doi.org/10.52711/0974-360x.2021.00405" @default.
• W3158538823 hasPublicationYear "2021" @default.
• W3158538823 type Work @default.
• W3158538823 sameAs 3158538823 @default.
• W3158538823 citedByCount "0" @default.
• W3158538823 crossrefType "journal-article" @default.
• W3158538823 hasAuthorship W3158538823A5000566569 @default.
• W3158538823 hasAuthorship W3158538823A5064384282 @default.
• W3158538823 hasAuthorship W3158538823A5065936802 @default.
• W3158538823 hasConcept C126322002 @default.
• W3158538823 hasConcept C134018914 @default.
• W3158538823 hasConcept C168563851 @default.
• W3158538823 hasConcept C2776478404 @default.
• W3158538823 hasConcept C2777180221 @default.
• W3158538823 hasConcept C2779284873 @default.
• W3158538823 hasConcept C2779306644 @default.
• W3158538823 hasConcept C2780323712 @default.
• W3158538823 hasConcept C2780473172 @default.
• W3158538823 hasConcept C2781308992 @default.
• W3158538823 hasConcept C2910068830 @default.
• W3158538823 hasConcept C555293320 @default.
• W3158538823 hasConcept C71924100 @default.
• W3158538823 hasConcept C90924648 @default.
• W3158538823 hasConceptScore W3158538823C126322002 @default.
• W3158538823 hasConceptScore W3158538823C134018914 @default.
• W3158538823 hasConceptScore W3158538823C168563851 @default.
• W3158538823 hasConceptScore W3158538823C2776478404 @default.
• W3158538823 hasConceptScore W3158538823C2777180221 @default.
• W3158538823 hasConceptScore W3158538823C2779284873 @default.
• W3158538823 hasConceptScore W3158538823C2779306644 @default.
• W3158538823 hasConceptScore W3158538823C2780323712 @default.
• W3158538823 hasConceptScore W3158538823C2780473172 @default.
• W3158538823 hasConceptScore W3158538823C2781308992 @default.
• W3158538823 hasConceptScore W3158538823C2910068830 @default.
• W3158538823 hasConceptScore W3158538823C555293320 @default.
• W3158538823 hasConceptScore W3158538823C71924100 @default.
• W3158538823 hasConceptScore W3158538823C90924648 @default.
• W3158538823 hasLocation W31585388231 @default.
• W3158538823 hasOpenAccess W3158538823 @default.
• W3158538823 hasPrimaryLocation W31585388231 @default.
• W3158538823 hasRelatedWork W2047379913 @default.
• W3158538823 hasRelatedWork W2090518035 @default.
• W3158538823 hasRelatedWork W2097893376 @default.
• W3158538823 hasRelatedWork W2109451951 @default.
• W3158538823 hasRelatedWork W2154928186 @default.
• W3158538823 hasRelatedWork W2344511577 @default.
• W3158538823 hasRelatedWork W2528689620 @default.
• W3158538823 hasRelatedWork W2756548008 @default.
• W3158538823 hasRelatedWork W4291003989 @default.
• W3158538823 hasRelatedWork W2199445251 @default.
• W3158538823 isParatext "false" @default.
• W3158538823 isRetracted "false" @default.
• W3158538823 magId "3158538823" @default.
• W3158538823 workType "article" @default.