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• W3158701645 abstract "Osmotic demyelinating syndrome (ODS) is a severe complication that occurs due to rapid correction of hyponatremia. Central pontine myelinolysis (CPM), in which a focus of demyelination occurs in the pontine region, and extrapontine myelinolysis (EPM), in which foci of demyelination appear in the white matter of the cerebral hemispheres, can be distinguished as a part of this syndrome. We describe two clinical cases of CPM that developed due to hyponatremia and hypokalemia in patients with SARS-CoV-2 infection (COVID-19). Differential diagnosis included acute disseminated encephalomyelitis, infectious encephalitis, and brain tumor. In both cases, a significant recovery of the lost functions was noted. The pathogenetic mechanisms of CPM development in patients with COVID-19 are discussed. ODS development in COVID- 19 necessitates strict control and correction of electrolyte disturbances in this category of patients in accordance with existing recommendations, which can reduce the risk of CPM." @default.
• W3158701645 created "2021-05-10" @default.
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• W3158701645 date "2021-04-25" @default.
• W3158701645 modified "2023-09-24" @default.
• W3158701645 title "Central pontine myelinolysis in the presence of SARS-CoV-2 infection (clinical observations)" @default.
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• W3158701645 doi "https://doi.org/10.14412/2074-2711-2021-2-91-96" @default.
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