FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3158721125> ?p ?o ?g. }

• W3158721125 abstract "Abstract miR-126 has been identified both as a tumor suppressor and an oncogene in different types of cancer. The aim of this study was to investigate the prognostic impact of miR-126-expression in colon cancer patients. Tumor tissue from 452 patients operated for stage I–III colon cancer was retrospectively collected and tissue microarrays were constructed. miR-126 expression was evaluated by in situ hybridization and analyzed using digital pathology. To isolate the compartment specific contribution of miR-126, tumor and adjacent tumor stroma were considered separately. In univariate analyses, high expression of miR-126 in tumor and stroma was related to increased disease-specific survival (p < 0.001 and p = 0.005, respectively). In multivariate analyses, high miR-126 expression in tumor remained a significant independent predictor of improved disease-specific survival (HR = 0.42, CI 0.23–0.75, p = 0.004). Within different TNM-stages there was a tendency towards the same results, but with statistically significant results in stage II only (p = 0.007). High expression of miR-126 is an independent positive prognostic factor in stage I–III colon cancer. This finding may be used to identify patients in need of adjuvant chemotherapy." @default.
• W3158721125 created "2021-05-10" @default.
• W3158721125 creator A5029902139 @default.
• W3158721125 creator A5080981252 @default.
• W3158721125 creator A5081738251 @default.
• W3158721125 creator A5084207494 @default.
• W3158721125 creator A5089005326 @default.
• W3158721125 date "2021-05-05" @default.
• W3158721125 modified "2023-10-15" @default.
• W3158721125 title "High expression of microRNA-126 relates to favorable prognosis for colon cancer patients" @default.
• W3158721125 cites W1877032126 @default.
• W3158721125 cites W1936021384 @default.
• W3158721125 cites W1960485012 @default.
• W3158721125 cites W1969337484 @default.
• W3158721125 cites W1989892200 @default.
• W3158721125 cites W2017650189 @default.
• W3158721125 cites W2032565321 @default.
• W3158721125 cites W2032923154 @default.
• W3158721125 cites W2059569578 @default.
• W3158721125 cites W2070583523 @default.
• W3158721125 cites W2099033223 @default.
• W3158721125 cites W2100258195 @default.
• W3158721125 cites W2119938514 @default.
• W3158721125 cites W2121708973 @default.
• W3158721125 cites W2124907137 @default.
• W3158721125 cites W2128077526 @default.
• W3158721125 cites W2129994868 @default.
• W3158721125 cites W2138657335 @default.
• W3158721125 cites W2157093199 @default.
• W3158721125 cites W2163294226 @default.
• W3158721125 cites W2164194749 @default.
• W3158721125 cites W2171232394 @default.
• W3158721125 cites W2344225782 @default.
• W3158721125 cites W2483222837 @default.
• W3158721125 cites W2807055401 @default.
• W3158721125 cites W2889646458 @default.
• W3158721125 cites W2952481429 @default.
• W3158721125 cites W3009963727 @default.
• W3158721125 cites W4249522930 @default.
• W3158721125 doi "https://doi.org/10.1038/s41598-021-87985-3" @default.
• W3158721125 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8100289" @default.
• W3158721125 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33953222" @default.
• W3158721125 hasPublicationYear "2021" @default.
• W3158721125 type Work @default.
• W3158721125 sameAs 3158721125 @default.
• W3158721125 citedByCount "5" @default.
• W3158721125 countsByYear W31587211252022 @default.
• W3158721125 countsByYear W31587211252023 @default.
• W3158721125 crossrefType "journal-article" @default.
• W3158721125 hasAuthorship W3158721125A5029902139 @default.
• W3158721125 hasAuthorship W3158721125A5080981252 @default.
• W3158721125 hasAuthorship W3158721125A5081738251 @default.
• W3158721125 hasAuthorship W3158721125A5084207494 @default.
• W3158721125 hasAuthorship W3158721125A5089005326 @default.
• W3158721125 hasBestOaLocation W31587211251 @default.
• W3158721125 hasConcept C104317684 @default.
• W3158721125 hasConcept C121608353 @default.
• W3158721125 hasConcept C126322002 @default.
• W3158721125 hasConcept C142724271 @default.
• W3158721125 hasConcept C143998085 @default.
• W3158721125 hasConcept C144301174 @default.
• W3158721125 hasConcept C145059251 @default.
• W3158721125 hasConcept C146357865 @default.
• W3158721125 hasConcept C151730666 @default.
• W3158721125 hasConcept C193270364 @default.
• W3158721125 hasConcept C204232928 @default.
• W3158721125 hasConcept C2779134260 @default.
• W3158721125 hasConcept C2781018059 @default.
• W3158721125 hasConcept C29537977 @default.
• W3158721125 hasConcept C38180746 @default.
• W3158721125 hasConcept C52124034 @default.
• W3158721125 hasConcept C526805850 @default.
• W3158721125 hasConcept C55493867 @default.
• W3158721125 hasConcept C71924100 @default.
• W3158721125 hasConcept C86803240 @default.
• W3158721125 hasConceptScore W3158721125C104317684 @default.
• W3158721125 hasConceptScore W3158721125C121608353 @default.
• W3158721125 hasConceptScore W3158721125C126322002 @default.
• W3158721125 hasConceptScore W3158721125C142724271 @default.
• W3158721125 hasConceptScore W3158721125C143998085 @default.
• W3158721125 hasConceptScore W3158721125C144301174 @default.
• W3158721125 hasConceptScore W3158721125C145059251 @default.
• W3158721125 hasConceptScore W3158721125C146357865 @default.
• W3158721125 hasConceptScore W3158721125C151730666 @default.
• W3158721125 hasConceptScore W3158721125C193270364 @default.
• W3158721125 hasConceptScore W3158721125C204232928 @default.
• W3158721125 hasConceptScore W3158721125C2779134260 @default.
• W3158721125 hasConceptScore W3158721125C2781018059 @default.
• W3158721125 hasConceptScore W3158721125C29537977 @default.
• W3158721125 hasConceptScore W3158721125C38180746 @default.
• W3158721125 hasConceptScore W3158721125C52124034 @default.
• W3158721125 hasConceptScore W3158721125C526805850 @default.
• W3158721125 hasConceptScore W3158721125C55493867 @default.
• W3158721125 hasConceptScore W3158721125C71924100 @default.
• W3158721125 hasConceptScore W3158721125C86803240 @default.
• W3158721125 hasIssue "1" @default.
• W3158721125 hasLocation W31587211251 @default.
• W3158721125 hasLocation W31587211252 @default.
• W3158721125 hasLocation W31587211253 @default.
• W3158721125 hasLocation W31587211254 @default.

• next