FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3158889221> ?p ?o ?g. }

• W3158889221 endingPage "1129" @default.
• W3158889221 startingPage "1120" @default.
• W3158889221 abstract "Non-small cell lung cancer (NSCLC) is a leading cause of cancer deaths. Its treatment includes specific oral tyrosine kinases inhibitors (TKIs).To estimate adherence and persistence among patients receiving TKIs and to assess the economic burden of the unused medicines in Alsace (France).This retrospective study was carried out using the Insurance Healthcare database.Adherence was calculated using medication possession ratio (MPR), persistence using estimated level of persistence with therapy (ELPT) and economic impact using prescription refill data.242 patients were receiving TKIs. The most common TKIs prescribed were erlotinib (75.6%, n = 183) and crizotinib (12.8%, n = 31). Total of 149 patients were included in the adherence analysis. Overall MPR was 0.98. 180 patients were included in the persistence analysis. Almost half of patients had stopped treatment at 60 days and only 38.3% (n = 69) were still persistent with the therapy at 120 days. The expenses related to unused TKIs amounted to €356,392 and were related majorly to treatment discontinuation followed by overlapping refills, patient deaths and dose- or drug-switching, respectively.Our data indicated overall adherence medicines above the acceptable limit of 0.80 but also pointed out a significant decline in persistence over time. The resulting economic losses justify the need for physicians and pharmacists to closely monitor their patients to ensure continuity of treatment. To limit the cost associated with unused medicines, interventions such as app-based monitoring, dispensing TKIs per unit over shorter periods and not only on monthly intervals could be implemented." @default.
• W3158889221 created "2021-05-10" @default.
• W3158889221 creator A5022092937 @default.
• W3158889221 creator A5053984097 @default.
• W3158889221 creator A5063067895 @default.
• W3158889221 creator A5081861523 @default.
• W3158889221 date "2021-04-24" @default.
• W3158889221 modified "2023-10-18" @default.
• W3158889221 title "Medication adherence and persistence among patients with non-small cell lung cancer receiving tyrosine kinase inhibitors and estimation of the economic burden associated with the unused medicines" @default.
• W3158889221 cites W1843179041 @default.
• W3158889221 cites W1905936368 @default.
• W3158889221 cites W1964238015 @default.
• W3158889221 cites W1970649882 @default.
• W3158889221 cites W1975901779 @default.
• W3158889221 cites W1985398792 @default.
• W3158889221 cites W2004198091 @default.
• W3158889221 cites W2018768095 @default.
• W3158889221 cites W2024127533 @default.
• W3158889221 cites W2036404617 @default.
• W3158889221 cites W2047143460 @default.
• W3158889221 cites W2047559808 @default.
• W3158889221 cites W2053780376 @default.
• W3158889221 cites W2056451421 @default.
• W3158889221 cites W2058662261 @default.
• W3158889221 cites W2063844762 @default.
• W3158889221 cites W2085211662 @default.
• W3158889221 cites W2119147452 @default.
• W3158889221 cites W2135785083 @default.
• W3158889221 cites W2136950115 @default.
• W3158889221 cites W2139062201 @default.
• W3158889221 cites W2149296859 @default.
• W3158889221 cites W2155441883 @default.
• W3158889221 cites W2273757369 @default.
• W3158889221 cites W2284819073 @default.
• W3158889221 cites W2346921980 @default.
• W3158889221 cites W2588675203 @default.
• W3158889221 cites W2614822972 @default.
• W3158889221 cites W2735369915 @default.
• W3158889221 cites W2789916977 @default.
• W3158889221 cites W2803688207 @default.
• W3158889221 cites W2886525607 @default.
• W3158889221 cites W2963520425 @default.
• W3158889221 cites W3122420327 @default.
• W3158889221 cites W4251572647 @default.
• W3158889221 doi "https://doi.org/10.1177/10781552211012452" @default.
• W3158889221 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33896267" @default.
• W3158889221 hasPublicationYear "2021" @default.
• W3158889221 type Work @default.
• W3158889221 sameAs 3158889221 @default.
• W3158889221 citedByCount "0" @default.
• W3158889221 crossrefType "journal-article" @default.
• W3158889221 hasAuthorship W3158889221A5022092937 @default.
• W3158889221 hasAuthorship W3158889221A5053984097 @default.
• W3158889221 hasAuthorship W3158889221A5063067895 @default.
• W3158889221 hasAuthorship W3158889221A5081861523 @default.
• W3158889221 hasConcept C121608353 @default.
• W3158889221 hasConcept C126322002 @default.
• W3158889221 hasConcept C127413603 @default.
• W3158889221 hasConcept C177713679 @default.
• W3158889221 hasConcept C187320778 @default.
• W3158889221 hasConcept C194828623 @default.
• W3158889221 hasConcept C2426938 @default.
• W3158889221 hasConcept C2776232967 @default.
• W3158889221 hasConcept C2776256026 @default.
• W3158889221 hasConcept C2778087573 @default.
• W3158889221 hasConcept C2778715236 @default.
• W3158889221 hasConcept C2779422266 @default.
• W3158889221 hasConcept C2779438470 @default.
• W3158889221 hasConcept C2781009140 @default.
• W3158889221 hasConcept C71924100 @default.
• W3158889221 hasConcept C98274493 @default.
• W3158889221 hasConceptScore W3158889221C121608353 @default.
• W3158889221 hasConceptScore W3158889221C126322002 @default.
• W3158889221 hasConceptScore W3158889221C127413603 @default.
• W3158889221 hasConceptScore W3158889221C177713679 @default.
• W3158889221 hasConceptScore W3158889221C187320778 @default.
• W3158889221 hasConceptScore W3158889221C194828623 @default.
• W3158889221 hasConceptScore W3158889221C2426938 @default.
• W3158889221 hasConceptScore W3158889221C2776232967 @default.
• W3158889221 hasConceptScore W3158889221C2776256026 @default.
• W3158889221 hasConceptScore W3158889221C2778087573 @default.
• W3158889221 hasConceptScore W3158889221C2778715236 @default.
• W3158889221 hasConceptScore W3158889221C2779422266 @default.
• W3158889221 hasConceptScore W3158889221C2779438470 @default.
• W3158889221 hasConceptScore W3158889221C2781009140 @default.
• W3158889221 hasConceptScore W3158889221C71924100 @default.
• W3158889221 hasConceptScore W3158889221C98274493 @default.
• W3158889221 hasIssue "5" @default.
• W3158889221 hasLocation W31588892211 @default.
• W3158889221 hasLocation W31588892212 @default.
• W3158889221 hasOpenAccess W3158889221 @default.
• W3158889221 hasPrimaryLocation W31588892211 @default.
• W3158889221 hasRelatedWork W1497144783 @default.
• W3158889221 hasRelatedWork W1803443763 @default.
• W3158889221 hasRelatedWork W2015138929 @default.
• W3158889221 hasRelatedWork W2016377334 @default.
• W3158889221 hasRelatedWork W2042683997 @default.
• W3158889221 hasRelatedWork W2047639006 @default.

• next