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• W3158892426 abstract "The cumulative knowledge of retina development has been instrumental in the generation of retinal organoid systems from pluripotent stem cells; and these three-dimensional organoid models, in turn, have provided unprecedented opportunities for retinal research and translational applications, including the ability to model disease in a human setting and to apply these models to the development and validation of therapeutic drugs. In this review article, we examine how retinal organoids can also contribute to our understanding of retinal developmental mechanisms, how this knowledge can be applied to modeling developmental abnormalities, and highlight some of the avenues that remain to be explored." @default.
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• W3158892426 date "2021-05-05" @default.
• W3158892426 modified "2023-10-10" @default.
• W3158892426 title "Organoids for the Study of Retinal Development and Developmental Abnormalities" @default.
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• W3158892426 doi "https://doi.org/10.3389/fncel.2021.667880" @default.
• W3158892426 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8131530" @default.
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• W3158892426 hasPublicationYear "2021" @default.
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