Matches in SemOpenAlex for { <https://semopenalex.org/work/W3158922793> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W3158922793 endingPage "103628" @default.
- W3158922793 startingPage "103628" @default.
- W3158922793 abstract "Facial nerves are frequently injured during cosmetic or other types of facial surgery. However, information on the genes involved in the damage and recovery of the facial nerves is limited. Here, we aimed to identify the genes affected by facial nerve injury and repair using next-generation sequencing. We established a rat axotomy model and a parallel epineurial neurorrhaphy model, in which gene expression was analyzed from 3 days to 8 weeks after surgery. We discovered that ARRB1, SGK1, and GSK3B genes associated with neuronal cell death were upregulated in the axotomy model. In contrast, MFRP, MDK, and ACE genes involved in neural recovery and regeneration exhibited higher expression in the neurorrhaphy model. In the present study, the analysis of the big data obtained from the next-generation sequencing (RNA-seq) technology reveals that the expression of genes involved in neuronal cell death is induced during nerve damage, and those associated with neural recovery are more abundantly expressed during repair processes. These results are considered to be useful for the establishment of the treatment of related diseases and basic research in various neuroscience fields by utilizing damage and recovery mechanism of facial nerves." @default.
- W3158922793 created "2021-05-10" @default.
- W3158922793 creator A5015212681 @default.
- W3158922793 creator A5026303073 @default.
- W3158922793 creator A5029290975 @default.
- W3158922793 creator A5043675651 @default.
- W3158922793 creator A5087509265 @default.
- W3158922793 date "2021-06-01" @default.
- W3158922793 modified "2023-09-23" @default.
- W3158922793 title "Identification of genes involved in neuronal cell death and recovery over time in rat axotomy and neurorrhaphy models through RNA sequencing" @default.
- W3158922793 cites W1967742032 @default.
- W3158922793 cites W1978007256 @default.
- W3158922793 cites W1978430338 @default.
- W3158922793 cites W1984055483 @default.
- W3158922793 cites W2002702896 @default.
- W3158922793 cites W2025872895 @default.
- W3158922793 cites W2034225169 @default.
- W3158922793 cites W2042379511 @default.
- W3158922793 cites W2057042766 @default.
- W3158922793 cites W2064496135 @default.
- W3158922793 cites W2064828626 @default.
- W3158922793 cites W2069238130 @default.
- W3158922793 cites W2087204404 @default.
- W3158922793 cites W2088911512 @default.
- W3158922793 cites W2112386956 @default.
- W3158922793 cites W2168744354 @default.
- W3158922793 cites W2289678372 @default.
- W3158922793 cites W2493798744 @default.
- W3158922793 cites W2552490836 @default.
- W3158922793 cites W2559847640 @default.
- W3158922793 cites W2566889811 @default.
- W3158922793 cites W2761045825 @default.
- W3158922793 cites W2769740873 @default.
- W3158922793 cites W2891221883 @default.
- W3158922793 cites W2950357250 @default.
- W3158922793 doi "https://doi.org/10.1016/j.mcn.2021.103628" @default.
- W3158922793 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33962001" @default.
- W3158922793 hasPublicationYear "2021" @default.
- W3158922793 type Work @default.
- W3158922793 sameAs 3158922793 @default.
- W3158922793 citedByCount "0" @default.
- W3158922793 crossrefType "journal-article" @default.
- W3158922793 hasAuthorship W3158922793A5015212681 @default.
- W3158922793 hasAuthorship W3158922793A5026303073 @default.
- W3158922793 hasAuthorship W3158922793A5029290975 @default.
- W3158922793 hasAuthorship W3158922793A5043675651 @default.
- W3158922793 hasAuthorship W3158922793A5087509265 @default.
- W3158922793 hasConcept C104317684 @default.
- W3158922793 hasConcept C105702510 @default.
- W3158922793 hasConcept C1491633281 @default.
- W3158922793 hasConcept C150194340 @default.
- W3158922793 hasConcept C169760540 @default.
- W3158922793 hasConcept C171056886 @default.
- W3158922793 hasConcept C2775991916 @default.
- W3158922793 hasConcept C2778987478 @default.
- W3158922793 hasConcept C2779683492 @default.
- W3158922793 hasConcept C2992459734 @default.
- W3158922793 hasConcept C54355233 @default.
- W3158922793 hasConcept C86803240 @default.
- W3158922793 hasConcept C95444343 @default.
- W3158922793 hasConceptScore W3158922793C104317684 @default.
- W3158922793 hasConceptScore W3158922793C105702510 @default.
- W3158922793 hasConceptScore W3158922793C1491633281 @default.
- W3158922793 hasConceptScore W3158922793C150194340 @default.
- W3158922793 hasConceptScore W3158922793C169760540 @default.
- W3158922793 hasConceptScore W3158922793C171056886 @default.
- W3158922793 hasConceptScore W3158922793C2775991916 @default.
- W3158922793 hasConceptScore W3158922793C2778987478 @default.
- W3158922793 hasConceptScore W3158922793C2779683492 @default.
- W3158922793 hasConceptScore W3158922793C2992459734 @default.
- W3158922793 hasConceptScore W3158922793C54355233 @default.
- W3158922793 hasConceptScore W3158922793C86803240 @default.
- W3158922793 hasConceptScore W3158922793C95444343 @default.
- W3158922793 hasLocation W31589227931 @default.
- W3158922793 hasLocation W31589227932 @default.
- W3158922793 hasOpenAccess W3158922793 @default.
- W3158922793 hasPrimaryLocation W31589227931 @default.
- W3158922793 hasRelatedWork W119979123 @default.
- W3158922793 hasRelatedWork W136774867 @default.
- W3158922793 hasRelatedWork W2009966535 @default.
- W3158922793 hasRelatedWork W2019454304 @default.
- W3158922793 hasRelatedWork W2373148611 @default.
- W3158922793 hasRelatedWork W2378262244 @default.
- W3158922793 hasRelatedWork W2996642893 @default.
- W3158922793 hasRelatedWork W3046272051 @default.
- W3158922793 hasRelatedWork W3107985572 @default.
- W3158922793 hasRelatedWork W3158922793 @default.
- W3158922793 hasVolume "113" @default.
- W3158922793 isParatext "false" @default.
- W3158922793 isRetracted "false" @default.
- W3158922793 magId "3158922793" @default.
- W3158922793 workType "article" @default.