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- W3159112056 endingPage "102475" @default.
- W3159112056 startingPage "102475" @default.
- W3159112056 abstract "Recent engineering technologies have transformed traditional perspectives of cancer to include the important role of the extracellular matrix (ECM) in recapitulating the malignant behaviors of cancer cells. Novel biomaterials and imaging technologies have advanced our understanding of the role of ECM density, structure, mechanics, and remodeling in tumor cell-ECM interactions in cancer biology and have provided new approaches in the development of cancer therapeutics. Here, we review emerging technologies in cancer ECM biology and recent advances in engineered systems for evaluating cancer therapeutics and provide new perspectives on how engineering tools present an opportunity for advancing the modeling and treatment of cancer. This review offers the cell biology and cancer cell biology communities insight into how engineering tools can improve our understanding of cancer ECM biology and therapeutic development." @default.
- W3159112056 created "2021-05-10" @default.
- W3159112056 creator A5023539776 @default.
- W3159112056 creator A5026268740 @default.
- W3159112056 creator A5078414342 @default.
- W3159112056 creator A5078659652 @default.
- W3159112056 date "2021-05-01" @default.
- W3159112056 modified "2023-10-18" @default.
- W3159112056 title "Emerging technologies provide insights on cancer extracellular matrix biology and therapeutics" @default.
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