Matches in SemOpenAlex for { <https://semopenalex.org/work/W3159132013> ?p ?o ?g. }
Showing items 1 to 60 of
60
with 100 items per page.
- W3159132013 abstract "The E3 ubiquitin ligases RING finger protein 43 (RNF43) and zinc and RING finger 3 (ZNRF3) have received great attention for their critical role in regulating WNT signalling during adult stem cell homeostasis. By promoting the turnover of WNT receptors, Frizzled and LRP5/6, RNF43 and ZNRF3 ensure that proper levels of WNT activity are maintained in stem cells. The molecular mechanism of RNF43/ZNRF3 activity is beginning to emerge from several recent studies, yet little is known about the regulation of RNF43/ZNRF3 at the post-translational level. A study in this issue of EMBO Reports identifies the deubiquitinating enzyme USP42 as a key regulator of WNT signalling, which acts by antagonizing the ubiquitin-dependent clearance of RNF43/ZNRF3 induced by R-spondins (Giebel et al, 2021)." @default.
- W3159132013 created "2021-05-10" @default.
- W3159132013 creator A5005310722 @default.
- W3159132013 creator A5009114158 @default.
- W3159132013 date "2021-05-03" @default.
- W3159132013 modified "2023-10-18" @default.
- W3159132013 title "Ub and Dub of RNF43/ZNRF3 in the WNT signalling pathway" @default.
- W3159132013 cites W1586218645 @default.
- W3159132013 cites W2078060536 @default.
- W3159132013 cites W2090789702 @default.
- W3159132013 cites W2092630678 @default.
- W3159132013 cites W2171977041 @default.
- W3159132013 cites W2621361823 @default.
- W3159132013 cites W2998808285 @default.
- W3159132013 cites W3048286720 @default.
- W3159132013 cites W3087660137 @default.
- W3159132013 cites W3140857766 @default.
- W3159132013 doi "https://doi.org/10.15252/embr.202152970" @default.
- W3159132013 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8097353" @default.
- W3159132013 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33938624" @default.
- W3159132013 hasPublicationYear "2021" @default.
- W3159132013 type Work @default.
- W3159132013 sameAs 3159132013 @default.
- W3159132013 citedByCount "8" @default.
- W3159132013 countsByYear W31591320132022 @default.
- W3159132013 countsByYear W31591320132023 @default.
- W3159132013 crossrefType "journal-article" @default.
- W3159132013 hasAuthorship W3159132013A5005310722 @default.
- W3159132013 hasAuthorship W3159132013A5009114158 @default.
- W3159132013 hasConcept C137620995 @default.
- W3159132013 hasConcept C39743133 @default.
- W3159132013 hasConcept C62478195 @default.
- W3159132013 hasConcept C70721500 @default.
- W3159132013 hasConcept C86803240 @default.
- W3159132013 hasConcept C95444343 @default.
- W3159132013 hasConceptScore W3159132013C137620995 @default.
- W3159132013 hasConceptScore W3159132013C39743133 @default.
- W3159132013 hasConceptScore W3159132013C62478195 @default.
- W3159132013 hasConceptScore W3159132013C70721500 @default.
- W3159132013 hasConceptScore W3159132013C86803240 @default.
- W3159132013 hasConceptScore W3159132013C95444343 @default.
- W3159132013 hasIssue "5" @default.
- W3159132013 hasLocation W31591320131 @default.
- W3159132013 hasOpenAccess W3159132013 @default.
- W3159132013 hasPrimaryLocation W31591320131 @default.
- W3159132013 hasRelatedWork W1978621971 @default.
- W3159132013 hasRelatedWork W1994979890 @default.
- W3159132013 hasRelatedWork W2027244603 @default.
- W3159132013 hasRelatedWork W2033081413 @default.
- W3159132013 hasRelatedWork W2035154210 @default.
- W3159132013 hasRelatedWork W2062621103 @default.
- W3159132013 hasRelatedWork W2118807251 @default.
- W3159132013 hasRelatedWork W2119987653 @default.
- W3159132013 hasRelatedWork W2370215344 @default.
- W3159132013 hasRelatedWork W3005710410 @default.
- W3159132013 hasVolume "22" @default.
- W3159132013 isParatext "false" @default.
- W3159132013 isRetracted "false" @default.
- W3159132013 magId "3159132013" @default.
- W3159132013 workType "article" @default.