Matches in SemOpenAlex for { <https://semopenalex.org/work/W3159200812> ?p ?o ?g. }
- W3159200812 endingPage "1472" @default.
- W3159200812 startingPage "1461" @default.
- W3159200812 abstract "Enantiomeric separation of six antihistamine agents was first systematically investigated on a cellulose-based chiral stationary phase (CSP), that is, cellulose tris-(3,5-dimethyl phenyl carbamate) (Chiralcel OD-RH), under the reversed-phase mode. Orphenadrine, meclizine, terfenadine, dioxopromethazine, and carbinoxamine enantiomers were completely separated under the optimized mobile phase conditions with resolutions of 5.02, 1.93, 1.68, 1.67, and 1.54, respectively. Mequitazine was partially separated with a resolution of 0.77. The influences of type and concentration of buffer salt, the pH of buffer solution, and the type and ratio of organic modifier on the chiral separation were evaluated and optimized. For a better insight into the enantiorecognition mechanisms, molecular docking was carried out via the Autodock software. The lowest binding energy and the optimal conformations of the analytes/CSP complexes were supplied, and the mechanisms of chiral recognition were determined. According to the results, the key interactions for the chiral recognition of these six analytes on CDMPC were π-π interactions, hydrophobic interactions, hydrogen bond interactions, and some special interactions." @default.
- W3159200812 created "2021-05-10" @default.
- W3159200812 creator A5034160514 @default.
- W3159200812 creator A5034950690 @default.
- W3159200812 creator A5087104530 @default.
- W3159200812 creator A5087873349 @default.
- W3159200812 date "2021-05-05" @default.
- W3159200812 modified "2023-10-14" @default.
- W3159200812 title "Chiral separation and molecular simulation study of six antihistamine agents on a coated cellulose tri‐(3,5‐dimethylphenycarbamate) column (Chiralcel OD‐RH) and its recognition mechanisms" @default.
- W3159200812 cites W123445147 @default.
- W3159200812 cites W130724958 @default.
- W3159200812 cites W1971547302 @default.
- W3159200812 cites W1976020325 @default.
- W3159200812 cites W1979054888 @default.
- W3159200812 cites W1989123522 @default.
- W3159200812 cites W2003731836 @default.
- W3159200812 cites W2023617358 @default.
- W3159200812 cites W2029402273 @default.
- W3159200812 cites W2031551127 @default.
- W3159200812 cites W2048200495 @default.
- W3159200812 cites W2056872455 @default.
- W3159200812 cites W2060705457 @default.
- W3159200812 cites W2062353537 @default.
- W3159200812 cites W2089115627 @default.
- W3159200812 cites W2163149425 @default.
- W3159200812 cites W2186460832 @default.
- W3159200812 cites W2326658044 @default.
- W3159200812 cites W2750646563 @default.
- W3159200812 cites W2792534970 @default.
- W3159200812 cites W2889814847 @default.
- W3159200812 cites W2906340960 @default.
- W3159200812 cites W2938724865 @default.
- W3159200812 cites W2943431265 @default.
- W3159200812 cites W2951640637 @default.
- W3159200812 cites W2967467422 @default.
- W3159200812 cites W2967814244 @default.
- W3159200812 cites W2972509128 @default.
- W3159200812 cites W2981417618 @default.
- W3159200812 cites W2982622091 @default.
- W3159200812 cites W2996550737 @default.
- W3159200812 cites W2998187107 @default.
- W3159200812 cites W3004337398 @default.
- W3159200812 cites W3005143171 @default.
- W3159200812 cites W3011036451 @default.
- W3159200812 cites W3013829782 @default.
- W3159200812 cites W3033445077 @default.
- W3159200812 cites W3034150508 @default.
- W3159200812 cites W3036341783 @default.
- W3159200812 cites W3039504136 @default.
- W3159200812 cites W3046181749 @default.
- W3159200812 cites W3047832171 @default.
- W3159200812 cites W3049575158 @default.
- W3159200812 cites W3083544511 @default.
- W3159200812 cites W3086541400 @default.
- W3159200812 cites W3090033945 @default.
- W3159200812 cites W3097707718 @default.
- W3159200812 cites W3101743654 @default.
- W3159200812 cites W3108583760 @default.
- W3159200812 cites W3109492076 @default.
- W3159200812 cites W3117057162 @default.
- W3159200812 cites W3120598260 @default.
- W3159200812 cites W3130936343 @default.
- W3159200812 cites W3132528981 @default.
- W3159200812 cites W4246766518 @default.
- W3159200812 doi "https://doi.org/10.1002/elps.202100033" @default.
- W3159200812 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33905565" @default.
- W3159200812 hasPublicationYear "2021" @default.
- W3159200812 type Work @default.
- W3159200812 sameAs 3159200812 @default.
- W3159200812 citedByCount "7" @default.
- W3159200812 countsByYear W31592008122021 @default.
- W3159200812 countsByYear W31592008122022 @default.
- W3159200812 countsByYear W31592008122023 @default.
- W3159200812 crossrefType "journal-article" @default.
- W3159200812 hasAuthorship W3159200812A5034160514 @default.
- W3159200812 hasAuthorship W3159200812A5034950690 @default.
- W3159200812 hasAuthorship W3159200812A5087104530 @default.
- W3159200812 hasAuthorship W3159200812A5087873349 @default.
- W3159200812 hasConcept C104317684 @default.
- W3159200812 hasConcept C112887158 @default.
- W3159200812 hasConcept C178790620 @default.
- W3159200812 hasConcept C185592680 @default.
- W3159200812 hasConcept C21951064 @default.
- W3159200812 hasConcept C2775905019 @default.
- W3159200812 hasConcept C2779251873 @default.
- W3159200812 hasConcept C2779303165 @default.
- W3159200812 hasConcept C2780152424 @default.
- W3159200812 hasConcept C2993377673 @default.
- W3159200812 hasConcept C32909587 @default.
- W3159200812 hasConcept C43617362 @default.
- W3159200812 hasConcept C486523 @default.
- W3159200812 hasConcept C54355233 @default.
- W3159200812 hasConcept C55493867 @default.
- W3159200812 hasConcept C86803240 @default.
- W3159200812 hasConceptScore W3159200812C104317684 @default.
- W3159200812 hasConceptScore W3159200812C112887158 @default.
- W3159200812 hasConceptScore W3159200812C178790620 @default.
- W3159200812 hasConceptScore W3159200812C185592680 @default.