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• W3159253249 endingPage "106400" @default.
• W3159253249 startingPage "106400" @default.
• W3159253249 abstract "Acute exacerbations of fibrosing interstitial lung disease (ILD) occur in both idiopathic pulmonary fibrosis (IPF) as well as non-IPF ILDs. An expert consensus definition has allowed for more frequent reporting of IPF exacerbations. The same is lacking for non-IPF ILD exacerbations. The incidence of non-IPF ILD exacerbations is likely less than in IPF, but the two entities share similar risk factors, such as increased frequency as physiologic derangements advance. The radiologic and histopathologic spectrum of acute ILD exacerbations extends from organizing pneumonia (OP) to the more treatment-refractory diffuse alveolar damage (DAD) pattern. Indeed, responsiveness to various therapies may depend on the relative components of these entities, favoring OP over DAD. There are no proven therapies for acute ILD exacerbations. Corticosteroids are a mainstay in any regimen although clear evidence of benefit does not exist. A variety of immunosuppressant agents have purported success in historical cohort studies - cyclophosphamide, cyclosporine A, and tacrolimus most commonly. Only one randomized controlled trial has been published, studying recombinant thrombomodulin for IPF exacerbation, but the primary outcome of survivor proportion at 90 days was not met. Other novel therapies for ILD exacerbations are still under investigation. The short and long-term prognosis of acute exacerbations of ILD is poor, especially in patients with IPF. Transplant referral should be considered early for both IPF as well as fibrosing non-IPF ILDs, given the unpredictability of the exacerbation event." @default.
• W3159253249 created "2021-05-10" @default.
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• W3159253249 date "2021-07-01" @default.
• W3159253249 modified "2023-10-10" @default.
• W3159253249 title "Characteristics and evaluation of acute exacerbations in chronic interstitial lung diseases" @default.
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• W3159253249 cites W1967896418 @default.
• W3159253249 cites W1974232992 @default.
• W3159253249 cites W1994240340 @default.
• W3159253249 cites W2011171956 @default.
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• W3159253249 cites W2015683287 @default.
• W3159253249 cites W2016204831 @default.
• W3159253249 cites W2026390886 @default.
• W3159253249 cites W2029109132 @default.
• W3159253249 cites W2031867428 @default.
• W3159253249 cites W2031872886 @default.
• W3159253249 cites W2040838979 @default.
• W3159253249 cites W2050851499 @default.
• W3159253249 cites W2051746621 @default.
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• W3159253249 cites W2078118974 @default.
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• W3159253249 doi "https://doi.org/10.1016/j.rmed.2021.106400" @default.
• W3159253249 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8144068" @default.
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• W3159253249 hasPublicationYear "2021" @default.
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