Matches in SemOpenAlex for { <https://semopenalex.org/work/W3159295005> ?p ?o ?g. }
Showing items 1 to 75 of
75
with 100 items per page.
- W3159295005 endingPage "236" @default.
- W3159295005 startingPage "231" @default.
- W3159295005 abstract "In our previous study (Kim et al, 1991), GLUT 4 protein content correlated negatively with plasma glucose levels in skeletal muscles of STZ-induced diabetic rats. Thus, in this study, to confirm whether expression of GLUT 4 correlate negatively with degree of hyperglycemia, we measured levels of GLUT 4 mRNA in red and white gastrocnemius muscles in STZ-induced mild and severe diabetic rats. Rats were randomly assigned to control, mild, and severe diabetic groups, and the diabetes was induced by intraperitoneal administration of STZ. The experiment was carried out 10 days after STZ administration. Gastrocnemius red and white muscles were used fur the measurement of GLUT 4 expression. Plasma glucose levels of mild and severe diabetic rats were increased compared to control rats (control, mild, and severe diabetes; 6.4±0.32, 9.4±0.68, and 22.0±0.58 mmol/L, respectively). Plasma insulin levels of mild and severe diabetic rats were decreased compared to control rats (control, mild, and severe diabetes; 198±37, l14±14, and 90±15 pmol/L, respectively). GLUT 4 mRNA levels of gastrocnemius red muscles in mild and severe diabetic rats were decreased compared to control rats (64±1.2% and 71±2.0% of control, respectively), but GLUT 4 mRNA levels in gastrocnemius white muscles were unaltered in diabetic rats. In summary, GLUT 4 mRNA levels were decreased in STZ-induced diabetic rats but did not correlated negatively with degree of hyperglycemia, and this result suggest that the regulatory mechanisms of decreased GLUT 4 mRNA levels are hypoinsulinemia and/or other metabolic factor but not hyperglycemia. And regulation of GLUT 4 expression in STZ-induced diabetes between red and white enriched skeletal muscles may be related to a fiber specific gene regulatory mechanism." @default.
- W3159295005 created "2021-05-10" @default.
- W3159295005 creator A5011728393 @default.
- W3159295005 creator A5012832662 @default.
- W3159295005 creator A5037894141 @default.
- W3159295005 creator A5038852974 @default.
- W3159295005 creator A5061854650 @default.
- W3159295005 creator A5069975635 @default.
- W3159295005 creator A5089328458 @default.
- W3159295005 date "1996-01-01" @default.
- W3159295005 modified "2023-09-24" @default.
- W3159295005 title "Decreased GLUT 4 mRNA Levels did not Related with Degree of Hyperglycemia in Skeletal Muscles of Streptozotocin-induced Diabetic Rats" @default.
- W3159295005 hasPublicationYear "1996" @default.
- W3159295005 type Work @default.
- W3159295005 sameAs 3159295005 @default.
- W3159295005 citedByCount "0" @default.
- W3159295005 crossrefType "journal-article" @default.
- W3159295005 hasAuthorship W3159295005A5011728393 @default.
- W3159295005 hasAuthorship W3159295005A5012832662 @default.
- W3159295005 hasAuthorship W3159295005A5037894141 @default.
- W3159295005 hasAuthorship W3159295005A5038852974 @default.
- W3159295005 hasAuthorship W3159295005A5061854650 @default.
- W3159295005 hasAuthorship W3159295005A5069975635 @default.
- W3159295005 hasAuthorship W3159295005A5089328458 @default.
- W3159295005 hasConcept C126322002 @default.
- W3159295005 hasConcept C134018914 @default.
- W3159295005 hasConcept C161573976 @default.
- W3159295005 hasConcept C2775872116 @default.
- W3159295005 hasConcept C2779280383 @default.
- W3159295005 hasConcept C2779306644 @default.
- W3159295005 hasConcept C2779959927 @default.
- W3159295005 hasConcept C3020574416 @default.
- W3159295005 hasConcept C555293320 @default.
- W3159295005 hasConcept C71924100 @default.
- W3159295005 hasConceptScore W3159295005C126322002 @default.
- W3159295005 hasConceptScore W3159295005C134018914 @default.
- W3159295005 hasConceptScore W3159295005C161573976 @default.
- W3159295005 hasConceptScore W3159295005C2775872116 @default.
- W3159295005 hasConceptScore W3159295005C2779280383 @default.
- W3159295005 hasConceptScore W3159295005C2779306644 @default.
- W3159295005 hasConceptScore W3159295005C2779959927 @default.
- W3159295005 hasConceptScore W3159295005C3020574416 @default.
- W3159295005 hasConceptScore W3159295005C555293320 @default.
- W3159295005 hasConceptScore W3159295005C71924100 @default.
- W3159295005 hasIssue "2" @default.
- W3159295005 hasLocation W31592950051 @default.
- W3159295005 hasOpenAccess W3159295005 @default.
- W3159295005 hasPrimaryLocation W31592950051 @default.
- W3159295005 hasRelatedWork W133214591 @default.
- W3159295005 hasRelatedWork W1992420001 @default.
- W3159295005 hasRelatedWork W2005875835 @default.
- W3159295005 hasRelatedWork W2013766983 @default.
- W3159295005 hasRelatedWork W2085374101 @default.
- W3159295005 hasRelatedWork W2087507486 @default.
- W3159295005 hasRelatedWork W2096973883 @default.
- W3159295005 hasRelatedWork W2099959517 @default.
- W3159295005 hasRelatedWork W2106562846 @default.
- W3159295005 hasRelatedWork W2111677322 @default.
- W3159295005 hasRelatedWork W2364066426 @default.
- W3159295005 hasRelatedWork W2366839496 @default.
- W3159295005 hasRelatedWork W2376262750 @default.
- W3159295005 hasRelatedWork W2382528626 @default.
- W3159295005 hasRelatedWork W2383406525 @default.
- W3159295005 hasRelatedWork W2387538062 @default.
- W3159295005 hasRelatedWork W2733899271 @default.
- W3159295005 hasRelatedWork W2989692550 @default.
- W3159295005 hasRelatedWork W3140563844 @default.
- W3159295005 hasRelatedWork W48044690 @default.
- W3159295005 hasVolume "30" @default.
- W3159295005 isParatext "false" @default.
- W3159295005 isRetracted "false" @default.
- W3159295005 magId "3159295005" @default.
- W3159295005 workType "article" @default.