Matches in SemOpenAlex for { <https://semopenalex.org/work/W3159298927> ?p ?o ?g. }
Showing items 1 to 49 of
49
with 100 items per page.
- W3159298927 abstract "Abstract Introduction: Bartter syndrome autosomal recessive renal tubular disorders usualy presents in infant age group or antenatallyCase Description64 years housewife, a known case of hypothyroidism with in emergency with generalized weakness and hypotension. She had an small adrenal nodule work up which showed that it was non functional. On evaluation at time of stress (blood pressure 70/50) her serum cortisol was 300nmol/l and she was therefore started on hydrocortisone. Her records revealed hypokalemia for last 2 years. Workup of hypokalemia showed kaliuresis, metabolic alkalosis, hypercalciuria and excess chloride excretion in the urine, suggestive of bartter’s syndrome. But this needed further confirmation as bartter’s is rare in this age group and also the test was done at the time of stress. She was started on spironolactone and oral potassium supplementation. CECT head done for evaluation of postural dizziness showed chronic cortical venous thrombosis. On follow up ACTH stimulated cortisol was done which showed normal cortisol level so steroid was stopped. She was readmitted one month later with hypokalemia(K-1.8 meq/l) while being on same dosage of spironolactone and potassium. Workup of hypokalemia showed same feature of bartter’s syndrome. Considering the chain of events, a suggestion of bartter’s and response to steroid, a diagnosis of acquired autoimmune bartter’s syndrome along with hypothyroidism was made. An autoimmune work up showed anti SCL 70 positive2+(++). Patient responded to steroid, spironolactone, indomethacin and oral potassium supplementation. Discussion: Bartter’s syndrome can rarely happen in old age too. Seek for autoimmune cause once we suspect acquired bartter’s. To best of our knowledge previously only one case has been reported of acquired Bartter with systemic sclerosis. Patient may develop systemic sclerosis in future as anti SCL70 antibody is very specific for it. It is positive in less than 1 % of general population. Anti SCL70 antibody is rarely positive in Sjogrens syndrome. Our patient did not feature of sjogren or systemic sclerosis even after 4 years follow up" @default.
- W3159298927 created "2021-05-10" @default.
- W3159298927 creator A5044120018 @default.
- W3159298927 creator A5087406937 @default.
- W3159298927 date "2021-05-01" @default.
- W3159298927 modified "2023-09-24" @default.
- W3159298927 title "A Rare Case Report of Acquired Bartters With Positive Anti Scl70 Antibody" @default.
- W3159298927 doi "https://doi.org/10.1210/jendso/bvab048.212" @default.
- W3159298927 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8089164" @default.
- W3159298927 hasPublicationYear "2021" @default.
- W3159298927 type Work @default.
- W3159298927 sameAs 3159298927 @default.
- W3159298927 citedByCount "0" @default.
- W3159298927 crossrefType "journal-article" @default.
- W3159298927 hasAuthorship W3159298927A5044120018 @default.
- W3159298927 hasAuthorship W3159298927A5087406937 @default.
- W3159298927 hasBestOaLocation W31592989271 @default.
- W3159298927 hasConcept C126322002 @default.
- W3159298927 hasConcept C134018914 @default.
- W3159298927 hasConcept C2776379505 @default.
- W3159298927 hasConcept C2778242168 @default.
- W3159298927 hasConcept C2778525890 @default.
- W3159298927 hasConcept C71924100 @default.
- W3159298927 hasConcept C90924648 @default.
- W3159298927 hasConceptScore W3159298927C126322002 @default.
- W3159298927 hasConceptScore W3159298927C134018914 @default.
- W3159298927 hasConceptScore W3159298927C2776379505 @default.
- W3159298927 hasConceptScore W3159298927C2778242168 @default.
- W3159298927 hasConceptScore W3159298927C2778525890 @default.
- W3159298927 hasConceptScore W3159298927C71924100 @default.
- W3159298927 hasConceptScore W3159298927C90924648 @default.
- W3159298927 hasLocation W31592989271 @default.
- W3159298927 hasLocation W31592989272 @default.
- W3159298927 hasOpenAccess W3159298927 @default.
- W3159298927 hasPrimaryLocation W31592989271 @default.
- W3159298927 hasRelatedWork W12653145 @default.
- W3159298927 hasRelatedWork W14958219 @default.
- W3159298927 hasRelatedWork W15208154 @default.
- W3159298927 hasRelatedWork W18535981 @default.
- W3159298927 hasRelatedWork W21398883 @default.
- W3159298927 hasRelatedWork W4070485 @default.
- W3159298927 hasRelatedWork W634995 @default.
- W3159298927 hasRelatedWork W6800933 @default.
- W3159298927 hasRelatedWork W9391726 @default.
- W3159298927 hasRelatedWork W4236744 @default.
- W3159298927 isParatext "false" @default.
- W3159298927 isRetracted "false" @default.
- W3159298927 magId "3159298927" @default.
- W3159298927 workType "article" @default.