FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3159644592> ?p ?o ?g. }

• W3159644592 abstract "The phytohormone abscisic acid (ABA) is crucial for plant responses to environmental challenges. The SNF1-regulated protein kinase 2s (SnRK2s) are key components in ABA-receptor coupled core signaling, and are rapidly phosphorylated and activated by ABA. Recent studies have suggested that Raf-like protein kinases (RAFs) participate in ABA-triggered SnRK2 activation. In vitro kinase assays also suggest the existence of autophosphorylation of SnRK2s. Thus, how SnRK2 kinases are quickly activated during ABA signaling still needs to be clarified. Here, we show that both B2 and B3 RAFs directly phosphorylate SnRK2.6 in the kinase activation loop. This transphosphorylation by RAFs is essential for SnRK2 activation. The activated SnRK2s then intermolecularly trans-phosphorylate other SnRK2s that are not yet activated to amplify the response. High-order Arabidopsis mutants lacking multiple B2 and B3 RAFs show ABA hyposensitivity. Our findings reveal a unique initiation and amplification mechanism of SnRK2 activation in ABA signaling in higher plants." @default.
• W3159644592 created "2021-05-10" @default.
• W3159644592 creator A5003060951 @default.
• W3159644592 creator A5003642006 @default.
• W3159644592 creator A5012477943 @default.
• W3159644592 creator A5016198996 @default.
• W3159644592 creator A5020563221 @default.
• W3159644592 creator A5029566368 @default.
• W3159644592 creator A5034915199 @default.
• W3159644592 creator A5035479883 @default.
• W3159644592 creator A5041076420 @default.
• W3159644592 creator A5049293054 @default.
• W3159644592 creator A5066813285 @default.
• W3159644592 creator A5073455600 @default.
• W3159644592 creator A5076587936 @default.
• W3159644592 creator A5077385497 @default.
• W3159644592 date "2021-04-28" @default.
• W3159644592 modified "2023-10-18" @default.
• W3159644592 title "Initiation and amplification of SnRK2 activation in abscisic acid signaling" @default.
• W3159644592 cites W1954288199 @default.
• W3159644592 cites W1974131529 @default.
• W3159644592 cites W1978838242 @default.
• W3159644592 cites W1995173597 @default.
• W3159644592 cites W1995176042 @default.
• W3159644592 cites W1997038372 @default.
• W3159644592 cites W2001734757 @default.
• W3159644592 cites W2010357923 @default.
• W3159644592 cites W2015065370 @default.
• W3159644592 cites W2020818362 @default.
• W3159644592 cites W2027375427 @default.
• W3159644592 cites W2054547140 @default.
• W3159644592 cites W2054946171 @default.
• W3159644592 cites W2056385567 @default.
• W3159644592 cites W2070049507 @default.
• W3159644592 cites W2075082022 @default.
• W3159644592 cites W2078929441 @default.
• W3159644592 cites W2096730448 @default.
• W3159644592 cites W2100596643 @default.
• W3159644592 cites W2102278945 @default.
• W3159644592 cites W2102842520 @default.
• W3159644592 cites W2106396116 @default.
• W3159644592 cites W2109907617 @default.
• W3159644592 cites W2111110205 @default.
• W3159644592 cites W2114104545 @default.
• W3159644592 cites W2114900530 @default.
• W3159644592 cites W2117548944 @default.
• W3159644592 cites W2122828310 @default.
• W3159644592 cites W2131271579 @default.
• W3159644592 cites W2133653666 @default.
• W3159644592 cites W2134526812 @default.
• W3159644592 cites W2137868236 @default.
• W3159644592 cites W2138193175 @default.
• W3159644592 cites W2139982792 @default.
• W3159644592 cites W2142175676 @default.
• W3159644592 cites W2148804923 @default.
• W3159644592 cites W2150783230 @default.
• W3159644592 cites W2156166308 @default.
• W3159644592 cites W2163657147 @default.
• W3159644592 cites W2165829183 @default.
• W3159644592 cites W2171463459 @default.
• W3159644592 cites W2221275951 @default.
• W3159644592 cites W2272955058 @default.
• W3159644592 cites W2762842128 @default.
• W3159644592 cites W2778077257 @default.
• W3159644592 cites W2788768491 @default.
• W3159644592 cites W2789898926 @default.
• W3159644592 cites W2800974204 @default.
• W3159644592 cites W2802959259 @default.
• W3159644592 cites W2807807130 @default.
• W3159644592 cites W2947422605 @default.
• W3159644592 cites W2970428551 @default.
• W3159644592 cites W2982261830 @default.
• W3159644592 cites W2995234753 @default.
• W3159644592 cites W2996745889 @default.
• W3159644592 cites W2998064682 @default.
• W3159644592 cites W3004072485 @default.
• W3159644592 cites W3011910616 @default.
• W3159644592 cites W3014815879 @default.
• W3159644592 cites W3049505402 @default.
• W3159644592 cites W3087664957 @default.
• W3159644592 cites W3095233590 @default.
• W3159644592 doi "https://doi.org/10.1038/s41467-021-22812-x" @default.
• W3159644592 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8080645" @default.
• W3159644592 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33911084" @default.
• W3159644592 hasPublicationYear "2021" @default.
• W3159644592 type Work @default.
• W3159644592 sameAs 3159644592 @default.
• W3159644592 citedByCount "67" @default.
• W3159644592 countsByYear W31596445922021 @default.
• W3159644592 countsByYear W31596445922022 @default.
• W3159644592 countsByYear W31596445922023 @default.
• W3159644592 crossrefType "journal-article" @default.
• W3159644592 hasAuthorship W3159644592A5003060951 @default.
• W3159644592 hasAuthorship W3159644592A5003642006 @default.
• W3159644592 hasAuthorship W3159644592A5012477943 @default.
• W3159644592 hasAuthorship W3159644592A5016198996 @default.
• W3159644592 hasAuthorship W3159644592A5020563221 @default.
• W3159644592 hasAuthorship W3159644592A5029566368 @default.
• W3159644592 hasAuthorship W3159644592A5034915199 @default.
• W3159644592 hasAuthorship W3159644592A5035479883 @default.

• next