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- W3159647569 endingPage "4525" @default.
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- W3159647569 abstract "Chromatin organization is developmentally regulated by epigenetic changes mediated by histone-modifying enzymes and chromatin remodeling complexes. In Drosophila melanogaster, the Tip60 chromatin remodeling complex (dTip60) play roles in chromatin regulation, which are shared by evolutionarily-related complexes identified in animal and plants. Recently, it was found that most subunits previously assigned to the dTip60 complex are shared by two related complexes, DOM-A.C and DOM-B.C, defined by DOM-A and DOM-B isoforms, respectively. In this work, we combined classical genetics, cell biology, and reverse genetics approaches to further investigate the biological roles played during Drosophila melanogaster development by a number of subunits originally assigned to the dTip60 complex." @default.
- W3159647569 created "2021-05-10" @default.
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- W3159647569 date "2021-04-26" @default.
- W3159647569 modified "2023-09-26" @default.
- W3159647569 title "In Vivo Silencing of Genes Coding for dTip60 Chromatin Remodeling Complex Subunits Affects Polytene Chromosome Organization and Proper Development in Drosophila melanogaster" @default.
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- W3159647569 doi "https://doi.org/10.3390/ijms22094525" @default.
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