Matches in SemOpenAlex for { <https://semopenalex.org/work/W3159774835> ?p ?o ?g. }
- W3159774835 endingPage "500" @default.
- W3159774835 startingPage "500" @default.
- W3159774835 abstract "Paclitaxel (PTX) is a chemotherapeutical agent commonly used to treat several kinds of cancer. PTX is known as a microtubule-targeting agent with a primary molecular mechanism that disrupts the dynamics of microtubules and induces mitotic arrest and cell death. Simultaneously, other mechanisms have been evaluated in many studies. Since the anticancer activity of PTX was discovered, it has been used to treat many cancer patients and has become one of the most extensively used anticancer drugs. Regrettably, the resistance of cancer to PTX is considered an extensive obstacle in clinical applications and is one of the major causes of death correlated with treatment failure. Therefore, the combination of PTX with other drugs could lead to efficient therapeutic strategies. Here, we summarize the mechanisms of PTX, and the current studies focusing on PTX and review promising combinations." @default.
- W3159774835 created "2021-05-10" @default.
- W3159774835 creator A5008094618 @default.
- W3159774835 creator A5011276365 @default.
- W3159774835 creator A5030327310 @default.
- W3159774835 creator A5042720093 @default.
- W3159774835 creator A5058962052 @default.
- W3159774835 creator A5074337396 @default.
- W3159774835 date "2021-05-02" @default.
- W3159774835 modified "2023-10-07" @default.
- W3159774835 title "Paclitaxel-Based Chemotherapy Targeting Cancer Stem Cells from Mono- to Combination Therapy" @default.
- W3159774835 cites W1596253574 @default.
- W3159774835 cites W1802717092 @default.
- W3159774835 cites W1870892629 @default.
- W3159774835 cites W1888700889 @default.
- W3159774835 cites W1892905988 @default.
- W3159774835 cites W1963614111 @default.
- W3159774835 cites W1964204964 @default.
- W3159774835 cites W1965467117 @default.
- W3159774835 cites W1965605561 @default.
- W3159774835 cites W1981058689 @default.
- W3159774835 cites W1983914017 @default.
- W3159774835 cites W1983933325 @default.
- W3159774835 cites W1984263030 @default.
- W3159774835 cites W1985495313 @default.
- W3159774835 cites W1986679409 @default.
- W3159774835 cites W1988555569 @default.
- W3159774835 cites W1989734503 @default.
- W3159774835 cites W1996308935 @default.
- W3159774835 cites W1998663218 @default.
- W3159774835 cites W1998728654 @default.
- W3159774835 cites W2003757313 @default.
- W3159774835 cites W2008318438 @default.
- W3159774835 cites W2008530649 @default.
- W3159774835 cites W2009139905 @default.
- W3159774835 cites W2009486292 @default.
- W3159774835 cites W2009761177 @default.
- W3159774835 cites W2011024910 @default.
- W3159774835 cites W2013510760 @default.
- W3159774835 cites W2013907429 @default.
- W3159774835 cites W2016101509 @default.
- W3159774835 cites W2016424446 @default.
- W3159774835 cites W2018835423 @default.
- W3159774835 cites W2020118391 @default.
- W3159774835 cites W2023113664 @default.
- W3159774835 cites W2026825995 @default.
- W3159774835 cites W2027259489 @default.
- W3159774835 cites W2028533496 @default.
- W3159774835 cites W2028593825 @default.
- W3159774835 cites W2033304578 @default.
- W3159774835 cites W2037490361 @default.
- W3159774835 cites W2037605675 @default.
- W3159774835 cites W2038784909 @default.
- W3159774835 cites W2043750157 @default.
- W3159774835 cites W2044433401 @default.
- W3159774835 cites W2045605237 @default.
- W3159774835 cites W2047259266 @default.
- W3159774835 cites W2048997359 @default.
- W3159774835 cites W2050188791 @default.
- W3159774835 cites W2050285145 @default.
- W3159774835 cites W2052399749 @default.
- W3159774835 cites W2052577429 @default.
- W3159774835 cites W2059022111 @default.
- W3159774835 cites W2060551076 @default.
- W3159774835 cites W2062069198 @default.
- W3159774835 cites W2062552900 @default.
- W3159774835 cites W2064164438 @default.
- W3159774835 cites W2066160200 @default.
- W3159774835 cites W2067299834 @default.
- W3159774835 cites W2067915666 @default.
- W3159774835 cites W2069059514 @default.
- W3159774835 cites W2077140502 @default.
- W3159774835 cites W2081410358 @default.
- W3159774835 cites W2087069906 @default.
- W3159774835 cites W2091133689 @default.
- W3159774835 cites W2096592126 @default.
- W3159774835 cites W2099450551 @default.
- W3159774835 cites W2106410559 @default.
- W3159774835 cites W2107436374 @default.
- W3159774835 cites W2107686567 @default.
- W3159774835 cites W2108929767 @default.
- W3159774835 cites W2110624293 @default.
- W3159774835 cites W2110969394 @default.
- W3159774835 cites W2117692326 @default.
- W3159774835 cites W2118758371 @default.
- W3159774835 cites W2119214893 @default.
- W3159774835 cites W2121411022 @default.
- W3159774835 cites W2121986702 @default.
- W3159774835 cites W2123789470 @default.
- W3159774835 cites W2125051098 @default.
- W3159774835 cites W2125089526 @default.
- W3159774835 cites W2132661761 @default.
- W3159774835 cites W2135503594 @default.
- W3159774835 cites W2136467633 @default.
- W3159774835 cites W2138309663 @default.
- W3159774835 cites W2139151018 @default.
- W3159774835 cites W2143740351 @default.
- W3159774835 cites W2144490545 @default.