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- W3159849462 abstract "A new sesquiterpene, chlorantholide G (1: ), a new sesquiterpene dimer, elatiolactone (2: ), and 2 new diterpenes, elatiorlabdane B (3: ) and elatiorlabdane C (4: ), together with 51 known compounds, were isolated from the aerial parts of Chloranthus elatior. The new structures including their absolute configurations were mainly established by mass spectrometric, NMR, and electronic circular dichroism experiments. All isolated compounds were tested for their anti-hDHODH activity. (4S,6R)-4-hydroxy-6-isopropyl-3-methylcyclohex-2-enone (5: ) and (4S,5R,9S,10R)-8(17),12,14-labdatrien-18-oic acid (29: ) were the most active compounds with IC50 values of 18.7 and 30.7 µM, respectively." @default.
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- W3159849462 date "2021-04-26" @default.
- W3159849462 modified "2023-10-02" @default.
- W3159849462 title "Chemical Constituents from Chloranthus elatior and Their Inhibitory Effect on Human Dihydroorotate Dehydrogenase" @default.
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- W3159849462 doi "https://doi.org/10.1055/a-1449-2642" @default.
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