Matches in SemOpenAlex for { <https://semopenalex.org/work/W3160216483> ?p ?o ?g. }
- W3160216483 endingPage "555" @default.
- W3160216483 startingPage "547" @default.
- W3160216483 abstract "To review recent findings and research directions on impulse control disorders and related behaviors (ICDRBs) in Parkinson's disease (PD).Longitudinal studies found that prevalence increases during PD progression, incident ICDRBs being around 10% per year in patients treated with dopaminergic therapies. Screening tools and severity scales already developed have been validated and are available in several countries and languages. The main clinical risk factors include young age, male gender, type, doses and duration of dopaminergic therapy, PD motor severity and dyskinesia, depression, anxiety, apathy, sleep disorders, and impulsivity traits. Genetic factors are suspected by a high estimated heritability, but individual genes and variants remain to be replicated. Management of ICDRBs is centered on dopamine agonist decrease, with the risk to develop withdrawal symptoms. Cognitive behavioral therapy and subthalamic nucleus deep brain stimulation also improve ICDRBs. In the perspective of precision medicine, new individual prediction models of these disorders have been proposed, but they need further independent replication.Regular monitoring of ICDRB during the course of PD is needed, particularly in the subject at high risk of developing these complications. Precision medicine will require the appropriate use of machine learning to be reached in the clinical setting." @default.
- W3160216483 created "2021-05-24" @default.
- W3160216483 creator A5042271343 @default.
- W3160216483 creator A5074748735 @default.
- W3160216483 creator A5078390423 @default.
- W3160216483 date "2021-05-06" @default.
- W3160216483 modified "2023-10-05" @default.
- W3160216483 title "Impulse control disorders and related behaviors in Parkinson's disease: risk factors, clinical and genetic aspects, and management" @default.
- W3160216483 cites W1530315344 @default.
- W3160216483 cites W1770207359 @default.
- W3160216483 cites W1839978507 @default.
- W3160216483 cites W1910174704 @default.
- W3160216483 cites W1965033221 @default.
- W3160216483 cites W1973092961 @default.
- W3160216483 cites W1975444516 @default.
- W3160216483 cites W1984340563 @default.
- W3160216483 cites W1984585186 @default.
- W3160216483 cites W1986602207 @default.
- W3160216483 cites W1988159999 @default.
- W3160216483 cites W1989151488 @default.
- W3160216483 cites W1990103681 @default.
- W3160216483 cites W1992423290 @default.
- W3160216483 cites W2008036532 @default.
- W3160216483 cites W2010051291 @default.
- W3160216483 cites W2021252898 @default.
- W3160216483 cites W2023263512 @default.
- W3160216483 cites W2035166610 @default.
- W3160216483 cites W2042584333 @default.
- W3160216483 cites W2043841807 @default.
- W3160216483 cites W2045769985 @default.
- W3160216483 cites W2049007948 @default.
- W3160216483 cites W2051015905 @default.
- W3160216483 cites W2051412332 @default.
- W3160216483 cites W2051861630 @default.
- W3160216483 cites W2052644168 @default.
- W3160216483 cites W2052902001 @default.
- W3160216483 cites W2058481315 @default.
- W3160216483 cites W2064169858 @default.
- W3160216483 cites W2074598021 @default.
- W3160216483 cites W2077726458 @default.
- W3160216483 cites W2086786733 @default.
- W3160216483 cites W2087361775 @default.
- W3160216483 cites W2089220395 @default.
- W3160216483 cites W2095868453 @default.
- W3160216483 cites W2096808934 @default.
- W3160216483 cites W2098032908 @default.
- W3160216483 cites W2098445519 @default.
- W3160216483 cites W2106966901 @default.
- W3160216483 cites W2108896002 @default.
- W3160216483 cites W2118841351 @default.
- W3160216483 cites W2127845308 @default.
- W3160216483 cites W2138881918 @default.
- W3160216483 cites W2139140411 @default.
- W3160216483 cites W2140978740 @default.
- W3160216483 cites W2142346040 @default.
- W3160216483 cites W2152767944 @default.
- W3160216483 cites W2153176667 @default.
- W3160216483 cites W2157796575 @default.
- W3160216483 cites W2158819247 @default.
- W3160216483 cites W2159697116 @default.
- W3160216483 cites W2160894339 @default.
- W3160216483 cites W2166233513 @default.
- W3160216483 cites W2168763579 @default.
- W3160216483 cites W2169150813 @default.
- W3160216483 cites W2284739415 @default.
- W3160216483 cites W2337617295 @default.
- W3160216483 cites W2390422647 @default.
- W3160216483 cites W2444534019 @default.
- W3160216483 cites W2466320100 @default.
- W3160216483 cites W2466387447 @default.
- W3160216483 cites W2504162177 @default.
- W3160216483 cites W2509349595 @default.
- W3160216483 cites W2513924437 @default.
- W3160216483 cites W2570773742 @default.
- W3160216483 cites W2578624245 @default.
- W3160216483 cites W2588008972 @default.
- W3160216483 cites W2595228832 @default.
- W3160216483 cites W2621873693 @default.
- W3160216483 cites W2751108263 @default.
- W3160216483 cites W2759247807 @default.
- W3160216483 cites W2763198934 @default.
- W3160216483 cites W2766605249 @default.
- W3160216483 cites W2783256082 @default.
- W3160216483 cites W2785782720 @default.
- W3160216483 cites W2790088231 @default.
- W3160216483 cites W2790856861 @default.
- W3160216483 cites W2793790523 @default.
- W3160216483 cites W2799634647 @default.
- W3160216483 cites W2799984449 @default.
- W3160216483 cites W2808883353 @default.
- W3160216483 cites W2811010029 @default.
- W3160216483 cites W2884670159 @default.
- W3160216483 cites W2885590196 @default.
- W3160216483 cites W2888856532 @default.
- W3160216483 cites W2898528414 @default.
- W3160216483 cites W2901519529 @default.
- W3160216483 cites W2901903538 @default.
- W3160216483 cites W2904845744 @default.