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- W3160337629 abstract "Migraine is a common neurological disorder with significant morbidity and disability. There is growing evidence that migraine is associated with cardiovascular diseases and stroke.The aim of this study was to provide an update on the association of migraine with some common vascular diseases in persons suffering from the disease and discuss the clinical implications.We searched PUBMED database using the MeSH terms Stroke, Coronary Artery Disease, Myocardial Ischemia, Atrial Fibrillation, White Matter and Dementia, Vascular, in combination with Migraine Disorders, Migraine with Aura and Migraine without Aura and reviewed the relevant studies. We studied articles mostly in English for the past 10 years, without excluding older articles that were relevant to this review. We also searched the reference lists of articles obtained and included some insightful reviews on 'Migraine and Vascular Risk'.The association between migraine and vascular diseases is strong and consistent for ischemic stroke and migraine with aura especially in young women, with oral contraceptive use and smoking. Although literature reports a higher prevalence of obesity, dyslipidemia, and family history of cardiovascular diseases in migraineurs, the 'migraine-vascular' connection persists in models where the traditional vascular risk factors are adjusted, implicating a migraine-specific pathophysiology at work. There is some evidence linking an adverse vascular risk factor profile to incident myocardial infarction in people with migraine. The association with hemorrhagic stroke is more variable.Although the absolute effect of migraine on 'vascular risks' is small, good practice parameters dwell on treating and reducing existing cardiovascular risk factors through lifestyle modification, encouraging smoking cessation, and advocating the wise use of agents like ergot alkaloids and oral contraceptives, after a risk-benefit analysis." @default.
- W3160337629 created "2021-05-24" @default.
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- W3160337629 date "2021-01-01" @default.
- W3160337629 modified "2023-09-27" @default.
- W3160337629 title "Migraine and Vascular Risk: An Update" @default.
- W3160337629 doi "https://doi.org/10.4103/0028-3886.315974" @default.
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- W3160337629 hasPublicationYear "2021" @default.
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