Matches in SemOpenAlex for { <https://semopenalex.org/work/W3160365847> ?p ?o ?g. }
- W3160365847 endingPage "123" @default.
- W3160365847 startingPage "104" @default.
- W3160365847 abstract "Eukaryotic cells use post-translational modifications to diversify and dynamically coordinate the function and properties of protein networks within various cellular processes. For example, the process of autophagy strongly depends on the balanced action of kinases and phosphatases. Highly conserved from the budding yeast Saccharomyces cerevisiae to humans, autophagy is a tightly regulated self-degradation process that is crucial for survival, stress adaptation, maintenance of cellular and organismal homeostasis, and cell differentiation and development. Many studies have emphasized the importance of kinases and phosphatases in the regulation of autophagy and identified many of the core autophagy proteins as their direct targets. In this review, we summarize the current knowledge on kinases and phosphatases acting on the core autophagy machinery and discuss the relevance of phosphoregulation for the overall process of autophagy." @default.
- W3160365847 created "2021-05-24" @default.
- W3160365847 creator A5004778008 @default.
- W3160365847 creator A5013116980 @default.
- W3160365847 creator A5022608936 @default.
- W3160365847 creator A5038185263 @default.
- W3160365847 date "2021-05-10" @default.
- W3160365847 modified "2023-10-17" @default.
- W3160365847 title "Phosphoregulation of the autophagy machinery by kinases and phosphatases" @default.
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