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• W3160690163 abstract "Type I interferon plays a critical role in the host response against virus infection, including Avibirnavirus. However, many viruses have developed multiple strategies to antagonize the innate host antiviral immune response during coevolution with the host. In this study, we first identified that K33-linked polyubiquitination of lysine-155 of TRAF3 enhances the interaction with TBK1, which positively regulates the host IFN immune response." @default.
• W3160690163 created "2021-05-24" @default.
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• W3160690163 date "2021-06-29" @default.
• W3160690163 modified "2023-10-18" @default.
• W3160690163 title "Inhibition of Antiviral Innate Immunity by <i>Avibirnavirus</i> VP3 via Blocking TBK1-TRAF3 Complex Formation and IRF3 Activation" @default.
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• W3160690163 doi "https://doi.org/10.1128/msystems.00016-21" @default.
• W3160690163 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8125067" @default.
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