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• W3160707035 abstract "Ribosome profiling (RiboSeq) has emerged as a powerful technique for studying the genome-wide regulation of translation in various cells. Several steps in the biological protocol have been improved, but the bioinformatics part of RiboSeq suffers from a lack of standardization, preventing the straightforward and complete reproduction of published results. Too many published studies provide insufficient detail about the bioinformatics pipeline used. The broad range of questions that can be asked with RiboSeq makes it difficult to use a single bioinformatics tool. Indeed, many scripts have been published for addressing diverse questions. Here (https://github.com/equipeGST/RiboDoc), we propose a unique tool (for use with multiple operating systems, OS) to standardize the general steps that must be performed systematically in RiboSeq analysis, together with the statistical analysis and quality control of the sample. The data generated can then be exploited with more specific tools. We hope that this tool will help to standardize bioinformatics analyses pipelines in the field of translation." @default.
• W3160707035 created "2021-05-24" @default.
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• W3160707035 date "2021-01-01" @default.
• W3160707035 modified "2023-10-17" @default.
• W3160707035 title "RiboDoc: A Docker-based package for ribosome profiling analysis" @default.
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• W3160707035 doi "https://doi.org/10.1016/j.csbj.2021.05.014" @default.
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