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- W3160875071 abstract "Significance: Hydrogen sulfide (H2S) is reported to be an important mediator involved in numerous physiological processes. H2S and hydropersulfides (RSSH) species are intimately linked biochemically. Therefore, interest in the mechanisms of the biological activity of H2S has led to investigations of the chemical biology of RSSH since they are likely to coexist in a biological system. Currently it is hypothesized that RSSH may be responsible for a least part of the observed H2S-mediated biology/physiology. Recent Advances: It has been recently touted that thiols (RSH) and RSSH have some important differences in terms of their chemical biology and that the generation of RSSH from RSH is purposeful to exploit these chemical differences as a response to a physiological or biological stress. This transformation may represent an unappreciated/unrecognized biological mechanism for dealing with cellular stresses. Critical Issues: Although recent studies indicate a diverse and potentially important chemical biology associated with RSSH species, these ideas have their foundations in early studies (some over 60 years old). It is vital to recognize the nature of this early work to fully appreciate the current ideas regarding RSSH biology. Importantly, these early studies were performed before the realization of purposeful H2S biosynthesis (before 1996). Future Directions: Taking clues from the past studies of RSSH chemistry and biology, progress in delineating the chemical biology of RSSH will continue. Determination of the possible relevance of RSSH chemical biology to signaling and cellular physiology will be a primary focus of many future studies. Antioxid. Redox Signal. 36, 244-255." @default.
- W3160875071 created "2021-05-24" @default.
- W3160875071 creator A5011599691 @default.
- W3160875071 date "2022-02-01" @default.
- W3160875071 modified "2023-10-16" @default.
- W3160875071 title "The Biological/Physiological Utility of Hydropersulfides (RSSH) and Related Species: What Is Old Is New Again" @default.
- W3160875071 cites W114952634 @default.
- W3160875071 cites W1488225405 @default.
- W3160875071 cites W1521628010 @default.
- W3160875071 cites W153595950 @default.
- W3160875071 cites W1543093457 @default.
- W3160875071 cites W1562324677 @default.
- W3160875071 cites W1599273508 @default.
- W3160875071 cites W1607667033 @default.
- W3160875071 cites W1636028712 @default.
- W3160875071 cites W1803143888 @default.
- W3160875071 cites W1969756298 @default.
- W3160875071 cites W1969838741 @default.
- W3160875071 cites W1970774413 @default.
- W3160875071 cites W1971142629 @default.
- W3160875071 cites W1977348409 @default.
- W3160875071 cites W1977988210 @default.
- W3160875071 cites W1980458823 @default.
- W3160875071 cites W1985556019 @default.
- W3160875071 cites W1986638123 @default.
- W3160875071 cites W1988846803 @default.
- W3160875071 cites W1998774601 @default.
- W3160875071 cites W1998861061 @default.
- W3160875071 cites W2003406318 @default.
- W3160875071 cites W2003918143 @default.
- W3160875071 cites W2005980540 @default.
- W3160875071 cites W2011629228 @default.
- W3160875071 cites W2013983549 @default.
- W3160875071 cites W2014301810 @default.
- W3160875071 cites W2017521727 @default.
- W3160875071 cites W2019613033 @default.
- W3160875071 cites W2024494769 @default.
- W3160875071 cites W2024615956 @default.
- W3160875071 cites W2028797694 @default.
- W3160875071 cites W2037965362 @default.
- W3160875071 cites W2040148126 @default.
- W3160875071 cites W2044644942 @default.
- W3160875071 cites W2048054979 @default.
- W3160875071 cites W2049948155 @default.
- W3160875071 cites W2052670031 @default.
- W3160875071 cites W2063700392 @default.
- W3160875071 cites W2065719143 @default.
- W3160875071 cites W2067683280 @default.
- W3160875071 cites W2071311359 @default.
- W3160875071 cites W2072540192 @default.
- W3160875071 cites W2081447694 @default.
- W3160875071 cites W2084967206 @default.
- W3160875071 cites W2088558219 @default.
- W3160875071 cites W2089894297 @default.
- W3160875071 cites W2090711642 @default.
- W3160875071 cites W2103880422 @default.
- W3160875071 cites W2114646837 @default.
- W3160875071 cites W2128595635 @default.
- W3160875071 cites W2141610173 @default.
- W3160875071 cites W2144175766 @default.
- W3160875071 cites W2150426398 @default.
- W3160875071 cites W2152466192 @default.
- W3160875071 cites W2162645036 @default.
- W3160875071 cites W2167562314 @default.
- W3160875071 cites W2168676830 @default.
- W3160875071 cites W2172161196 @default.
- W3160875071 cites W2191665487 @default.
- W3160875071 cites W2256535334 @default.
- W3160875071 cites W2275172713 @default.
- W3160875071 cites W2310326621 @default.
- W3160875071 cites W2313014508 @default.
- W3160875071 cites W2316157815 @default.
- W3160875071 cites W2321390884 @default.
- W3160875071 cites W2323866605 @default.
- W3160875071 cites W2344272205 @default.
- W3160875071 cites W2405848654 @default.
- W3160875071 cites W2407469013 @default.
- W3160875071 cites W2413607016 @default.
- W3160875071 cites W2467056461 @default.
- W3160875071 cites W2522668658 @default.
- W3160875071 cites W2588354883 @default.
- W3160875071 cites W2602090284 @default.
- W3160875071 cites W2606353696 @default.
- W3160875071 cites W2606853011 @default.
- W3160875071 cites W2617348788 @default.
- W3160875071 cites W2766780446 @default.
- W3160875071 cites W2767914703 @default.
- W3160875071 cites W2786677683 @default.
- W3160875071 cites W2802985983 @default.
- W3160875071 cites W2805775075 @default.
- W3160875071 cites W2892533751 @default.
- W3160875071 cites W2913288741 @default.
- W3160875071 cites W2915542748 @default.
- W3160875071 cites W2967009964 @default.
- W3160875071 cites W2977567376 @default.
- W3160875071 cites W3000776204 @default.
- W3160875071 cites W3008232375 @default.
- W3160875071 cites W3037452262 @default.