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- W3160882039 abstract "Polymorphism of GSTT1 had been known to be associated with nasopharyngeal carcinoma. The polymorphism induces oxidative stress and enhances IgA level through increasing EBV lytic reactivation. IgA levels are important for screening NPC patients and also for consideration of NPC therapy. We did the study to analyze the correlation of GSTT1 polymorphism and IgA level. This study was an analytical study with a cross-sectional design. We used the blood of NPC patients and identified GSTT1 polymorphism by PCR and IgA level by ELISA. There were 18 (62.0%) patients with GSTT1 null and 11 (38.0%) patients with GSTT1 positive. Patients with increased IgA were 21 (72.4%) patients, and normal IgA were 8 (27.6%) patients. There was no significant association of GSTT1 polymorphism with the IgA level. These can be affected by other factors, including the antioxidant level of NPC patients. The study could be used as an initial study for identifying the association of other risk factors with the IgA level of NPC patients." @default.
- W3160882039 created "2021-05-24" @default.
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- W3160882039 date "2021-01-01" @default.
- W3160882039 modified "2023-10-17" @default.
- W3160882039 title "The association of GSTT1 polymorphism with immunoglobulin a (IgA) of nasopharyngeal carcinoma patients" @default.
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- W3160882039 doi "https://doi.org/10.1063/5.0045626" @default.
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