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- W3161202912 abstract "Certain members of the gut microbiota exhibit diurnal variations in relative abundance and function to serve as non-canonical drivers of host circadian rhythms and metabolism. Also known as microbial oscillators, these microorganisms entrain upon non-photic cues, primarily dietary, to modulate host metabolism by providing input to both circadian clock-dependent and clock-independent host networks. Microbial oscillators are generally promoted by plant-based, low-fat (lean) diets, and most are abolished by low-fibre, high-sugar, high-fat (Western) diets. The changes in microbial oscillators under different diets then affect host metabolism by altering central and peripheral host circadian clock functions and/or by directly affecting other metabolic targets. Here, we review the unique role of the gut microbiota as a non-photic regulator of host circadian rhythms and metabolism. We describe genetic, environmental, dietary and other host factors such as sex and gut immunity that determine the composition and behaviour of microbial oscillators. The mechanisms by which these oscillators regulate host circadian gene expression and metabolic state are further discussed. Because of the gut microbiota's unique role as a non-photic driver of host metabolism and circadian rhythms, the development and clinical application of novel gut microbiota-related diagnostics and therapeutics hold great promise for achieving and maintaining metabolic health." @default.
- W3161202912 created "2021-05-24" @default.
- W3161202912 creator A5042231260 @default.
- W3161202912 creator A5078853648 @default.
- W3161202912 creator A5080665666 @default.
- W3161202912 date "2021-05-17" @default.
- W3161202912 modified "2023-10-11" @default.
- W3161202912 title "Gut microbiota as a transducer of dietary cues to regulate host circadian rhythms and metabolism" @default.
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- W3161202912 cites W1596600993 @default.
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- W3161202912 cites W1878348163 @default.
- W3161202912 cites W1902150932 @default.
- W3161202912 cites W1920510593 @default.
- W3161202912 cites W1972571170 @default.
- W3161202912 cites W1976540475 @default.
- W3161202912 cites W1976578226 @default.
- W3161202912 cites W1980682199 @default.
- W3161202912 cites W1981500982 @default.
- W3161202912 cites W1990356462 @default.
- W3161202912 cites W1991932125 @default.
- W3161202912 cites W1995200202 @default.
- W3161202912 cites W2016539998 @default.
- W3161202912 cites W2022336568 @default.
- W3161202912 cites W2023597944 @default.
- W3161202912 cites W2026930722 @default.
- W3161202912 cites W2044458189 @default.
- W3161202912 cites W2051984731 @default.
- W3161202912 cites W2054066779 @default.
- W3161202912 cites W2058237889 @default.
- W3161202912 cites W2071886628 @default.
- W3161202912 cites W2077553363 @default.
- W3161202912 cites W2083279903 @default.
- W3161202912 cites W2089177264 @default.
- W3161202912 cites W2091379168 @default.
- W3161202912 cites W2091673549 @default.
- W3161202912 cites W2103049241 @default.
- W3161202912 cites W2104266531 @default.
- W3161202912 cites W2116103211 @default.
- W3161202912 cites W2117296173 @default.
- W3161202912 cites W2123345709 @default.
- W3161202912 cites W2135217576 @default.
- W3161202912 cites W2140233939 @default.
- W3161202912 cites W2140832481 @default.
- W3161202912 cites W2147712103 @default.
- W3161202912 cites W2163531378 @default.
- W3161202912 cites W2164628441 @default.
- W3161202912 cites W2165407190 @default.
- W3161202912 cites W2190320496 @default.
- W3161202912 cites W2238743437 @default.
- W3161202912 cites W2428071229 @default.
- W3161202912 cites W2440558121 @default.
- W3161202912 cites W2460141262 @default.
- W3161202912 cites W2480707776 @default.
- W3161202912 cites W2554298640 @default.
- W3161202912 cites W2557764746 @default.
- W3161202912 cites W2559454592 @default.
- W3161202912 cites W2569429048 @default.
- W3161202912 cites W2596246619 @default.
- W3161202912 cites W2735071218 @default.
- W3161202912 cites W2743339141 @default.
- W3161202912 cites W2751705979 @default.
- W3161202912 cites W2763638682 @default.
- W3161202912 cites W2771465307 @default.
- W3161202912 cites W2796527107 @default.
- W3161202912 cites W2798049216 @default.
- W3161202912 cites W2799787925 @default.
- W3161202912 cites W2807101949 @default.
- W3161202912 cites W2884737885 @default.
- W3161202912 cites W2890960550 @default.
- W3161202912 cites W2897926834 @default.
- W3161202912 cites W2899391538 @default.
- W3161202912 cites W2901106636 @default.
- W3161202912 cites W2911328532 @default.
- W3161202912 cites W2937524131 @default.
- W3161202912 cites W2945653989 @default.
- W3161202912 cites W2947598565 @default.
- W3161202912 cites W2949668662 @default.
- W3161202912 cites W2972332951 @default.
- W3161202912 cites W2975185045 @default.
- W3161202912 cites W2992787906 @default.
- W3161202912 cites W2996013185 @default.
- W3161202912 cites W2999037967 @default.
- W3161202912 cites W3006040663 @default.
- W3161202912 cites W3013965112 @default.
- W3161202912 cites W3036173253 @default.
- W3161202912 cites W3039530833 @default.
- W3161202912 cites W3111465292 @default.
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- W3161202912 doi "https://doi.org/10.1038/s41575-021-00452-2" @default.
- W3161202912 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8521648" @default.
- W3161202912 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34002082" @default.
- W3161202912 hasPublicationYear "2021" @default.
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