FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3161252129> ?p ?o ?g. }

• W3161252129 endingPage "105278" @default.
• W3161252129 startingPage "105278" @default.
• W3161252129 abstract "Hypoandrogenic men showed a higher prevalence of major depressive disorder (MDD), which could be ascribed to overlapping symptoms such as sexual dysfunction, or additionally to core emotional symptoms such as sadness and anhedonia. We examined whether androgen levels 1) differ between men with and without MDD cross-sectionally, 2) are associated with an elevated risk for onset of MDD prospectively, and 3) associate with all individual MDD symptoms, or only with hypogonadism overlapping symptoms.In 823 men (mean age 43.5 years), baseline plasma levels of total testosterone, 5α-dihydrotestosterone (5α-DHT), and androstenedione were determined with liquid chromatography-tandem mass spectrometry, and dehydroepiandrosterone-sulphate (DHEAS) and sex hormone binding globulin with radioimmunoassay, whereas free testosterone was calculated. MDD status was assessed at baseline and after two years using structured interviews and individual MDD symptoms were self-rated at baseline, and after one and two years.None of the androgen levels were associated with current or onset (incidence or recurrence) of MDD. Free testosterone was only inversely associated with interest in sex. Also, androstenedione and DHEAS were positively associated with some individual MDD symptoms, and 5α-DHT levels showed non-linear associations (both with low and high levels) with MDD symptom severity and several individual MDD symptoms.These results support the idea that circulating androgens synthesised by the testes are of limited clinical relevance to MDD in adult men, but levels of androstenedione, DHEAS and 5α-DHT may be associated with some individual MDD symptoms." @default.
• W3161252129 created "2021-05-24" @default.
• W3161252129 creator A5016729649 @default.
• W3161252129 creator A5026480246 @default.
• W3161252129 creator A5030799981 @default.
• W3161252129 creator A5043197939 @default.
• W3161252129 creator A5055183685 @default.
• W3161252129 creator A5081042689 @default.
• W3161252129 creator A5090875089 @default.
• W3161252129 date "2021-08-01" @default.
• W3161252129 modified "2023-10-16" @default.
• W3161252129 title "Plasma androgens and the presence and course of depression in a large cohort of men" @default.
• W3161252129 cites W1548930453 @default.
• W3161252129 cites W1596515083 @default.
• W3161252129 cites W1972737331 @default.
• W3161252129 cites W1976003215 @default.
• W3161252129 cites W1977417329 @default.
• W3161252129 cites W1992889320 @default.
• W3161252129 cites W1999743362 @default.
• W3161252129 cites W2000053835 @default.
• W3161252129 cites W2000300562 @default.
• W3161252129 cites W2010580322 @default.
• W3161252129 cites W2021682647 @default.
• W3161252129 cites W2021776310 @default.
• W3161252129 cites W2032742357 @default.
• W3161252129 cites W2033572273 @default.
• W3161252129 cites W2043480169 @default.
• W3161252129 cites W2075287300 @default.
• W3161252129 cites W2081886505 @default.
• W3161252129 cites W2096237552 @default.
• W3161252129 cites W2098247759 @default.
• W3161252129 cites W2122434629 @default.
• W3161252129 cites W2124084192 @default.
• W3161252129 cites W2127857741 @default.
• W3161252129 cites W2151595908 @default.
• W3161252129 cites W2151631674 @default.
• W3161252129 cites W2178662781 @default.
• W3161252129 cites W2209426968 @default.
• W3161252129 cites W2229586988 @default.
• W3161252129 cites W2494154936 @default.
• W3161252129 cites W2569498020 @default.
• W3161252129 cites W2610765860 @default.
• W3161252129 cites W2619983498 @default.
• W3161252129 cites W2791298691 @default.
• W3161252129 cites W3004418682 @default.
• W3161252129 doi "https://doi.org/10.1016/j.psyneuen.2021.105278" @default.
• W3161252129 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34049017" @default.
• W3161252129 hasPublicationYear "2021" @default.
• W3161252129 type Work @default.
• W3161252129 sameAs 3161252129 @default.
• W3161252129 citedByCount "4" @default.
• W3161252129 countsByYear W31612521292022 @default.
• W3161252129 countsByYear W31612521292023 @default.
• W3161252129 crossrefType "journal-article" @default.
• W3161252129 hasAuthorship W3161252129A5016729649 @default.
• W3161252129 hasAuthorship W3161252129A5026480246 @default.
• W3161252129 hasAuthorship W3161252129A5030799981 @default.
• W3161252129 hasAuthorship W3161252129A5043197939 @default.
• W3161252129 hasAuthorship W3161252129A5055183685 @default.
• W3161252129 hasAuthorship W3161252129A5081042689 @default.
• W3161252129 hasAuthorship W3161252129A5090875089 @default.
• W3161252129 hasBestOaLocation W31612521291 @default.
• W3161252129 hasConcept C126322002 @default.
• W3161252129 hasConcept C134018914 @default.
• W3161252129 hasConcept C139719470 @default.
• W3161252129 hasConcept C15744967 @default.
• W3161252129 hasConcept C162324750 @default.
• W3161252129 hasConcept C2776683971 @default.
• W3161252129 hasConcept C2776867660 @default.
• W3161252129 hasConcept C2776992908 @default.
• W3161252129 hasConcept C2777911890 @default.
• W3161252129 hasConcept C2778941446 @default.
• W3161252129 hasConcept C2779144063 @default.
• W3161252129 hasConcept C2779279991 @default.
• W3161252129 hasConcept C2779881493 @default.
• W3161252129 hasConcept C2780051608 @default.
• W3161252129 hasConcept C513476851 @default.
• W3161252129 hasConcept C71315377 @default.
• W3161252129 hasConcept C71924100 @default.
• W3161252129 hasConceptScore W3161252129C126322002 @default.
• W3161252129 hasConceptScore W3161252129C134018914 @default.
• W3161252129 hasConceptScore W3161252129C139719470 @default.
• W3161252129 hasConceptScore W3161252129C15744967 @default.
• W3161252129 hasConceptScore W3161252129C162324750 @default.
• W3161252129 hasConceptScore W3161252129C2776683971 @default.
• W3161252129 hasConceptScore W3161252129C2776867660 @default.
• W3161252129 hasConceptScore W3161252129C2776992908 @default.
• W3161252129 hasConceptScore W3161252129C2777911890 @default.
• W3161252129 hasConceptScore W3161252129C2778941446 @default.
• W3161252129 hasConceptScore W3161252129C2779144063 @default.
• W3161252129 hasConceptScore W3161252129C2779279991 @default.
• W3161252129 hasConceptScore W3161252129C2779881493 @default.
• W3161252129 hasConceptScore W3161252129C2780051608 @default.
• W3161252129 hasConceptScore W3161252129C513476851 @default.
• W3161252129 hasConceptScore W3161252129C71315377 @default.
• W3161252129 hasConceptScore W3161252129C71924100 @default.
• W3161252129 hasFunder F4320320929 @default.
• W3161252129 hasFunder F4320320933 @default.

• next