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- W3161368280 abstract "Abstract Micro-CT provides critical data for musculoskeletal research, yielding three-dimensional datasets containing distributions of mineral density. Using high-resolution scans, we quantified changes in the fine architecture of bone in the spine of young mice. This data is made available as a reference to physiological cancellous bone growth. The scans (n = 19) depict the extensive structural changes typical for female C57BL/6 mice pups, aged 1-, 3-, 7-, 10- and 14-days post-partum, as they attain the mature geometry. We reveal the micro-morphology down to individual trabeculae in the spine that follow phases of mineral-tissue rearrangement in the growing lumbar vertebra on a micrometer length scale. Phantom data is provided to facilitate mineral density calibration. Conventional histomorphometry matched with our micro-CT data on selected samples confirms the validity and accuracy of our 3D scans. The data may thus serve as a reference for modeling normal bone growth and can be used to benchmark other experiments assessing the effects of biomaterials, tissue growth, healing, and regeneration." @default.
- W3161368280 created "2021-05-24" @default.
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- W3161368280 date "2021-05-14" @default.
- W3161368280 modified "2023-10-01" @default.
- W3161368280 title "Micro-CT data of early physiological cancellous bone formation in the lumbar spine of female C57BL/6 mice" @default.
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- W3161368280 doi "https://doi.org/10.1038/s41597-021-00913-y" @default.
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