FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3162128797> ?p ?o ?g. }

• W3162128797 abstract "The prognostic value of human leukocyte antigen G (HLA-G) expression in gastrointestinal (GI) cancers remains controversial. Thus, this meta-analysis aimed to summarize available evidence from case-control or cohort studies that evaluated this association.The PubMed, EMBASE, Cochrane Library, and Web of Science databases were searched to identify relevant studies written in English published up to April 1, 2021, and with no initial date. Furthermore, the Google Scholar and Google databases were also searched manually for gray literature. The protocol for this meta-analysis was registered at PROSPERO (CRD42020213411). Pooled hazard ratios (HRs) or odds ratios (ORs) and 95% confidence intervals (CIs) were estimated for end points using fixed- and random-effects statistical models to account for heterogeneity. Publication bias was evaluated using a funnel plot, Begg's and Egger's tests, and the trim and fill method.A total of 30 eligible articles with 5737 unique patients, including 12 studies on colorectal cancer (CRC), 6 on gastric cancer (GC), 5 on esophageal cancer (ESCC), 5 on hepatocellular carcinoma (HCC), and 2 on pancreatic adenocarcinoma (PC), were retrieved. Both univariate (HR = 2.01, 95% CI: 1.48 ~ 2.72) and multivariate (HR = 2.69, 95% CI: 2.03 ~ 3.55) analyses revealed that HLA-G expression was significantly correlated with poor overall survival (OS), regardless of the cancer type or antibody used. Subgroup analysis stratified by antibody showed that the 4H84 (I2 = 45.8%, P = 0.101) antibodies could be trustworthy and reliable for detecting HLA-G expression in GI cancers. In addition, HLA-G expression was found to be correlated with adverse clinicopathological parameters such as clinical stage, nodal status, metastasis, and histological grade but not tumor status.Elevated HLA-G expression indicates a poor prognosis for GI cancer patients, and screening for this marker could allow for the early diagnosis and treatment of GI cancers to improve survival rates." @default.
• W3162128797 created "2021-05-24" @default.
• W3162128797 creator A5015845150 @default.
• W3162128797 creator A5032781939 @default.
• W3162128797 creator A5053444775 @default.
• W3162128797 creator A5056741906 @default.
• W3162128797 creator A5059439308 @default.
• W3162128797 creator A5071703986 @default.
• W3162128797 creator A5071802715 @default.
• W3162128797 date "2021-05-12" @default.
• W3162128797 modified "2023-09-25" @default.
• W3162128797 title "Prognostic and Clinicopathological Value of Human Leukocyte Antigen G in Gastrointestinal Cancers: A Meta-Analysis" @default.
• W3162128797 cites W138410924 @default.
• W3162128797 cites W146669819 @default.
• W3162128797 cites W1572267688 @default.
• W3162128797 cites W1967263426 @default.
• W3162128797 cites W1978667884 @default.
• W3162128797 cites W1993215425 @default.
• W3162128797 cites W2002220805 @default.
• W3162128797 cites W2009328663 @default.
• W3162128797 cites W2017824838 @default.
• W3162128797 cites W2021404670 @default.
• W3162128797 cites W2021582501 @default.
• W3162128797 cites W2021902701 @default.
• W3162128797 cites W2023485480 @default.
• W3162128797 cites W2023923460 @default.
• W3162128797 cites W2035155248 @default.
• W3162128797 cites W2039339794 @default.
• W3162128797 cites W2047056707 @default.
• W3162128797 cites W2054213815 @default.
• W3162128797 cites W2055760702 @default.
• W3162128797 cites W2059841890 @default.
• W3162128797 cites W2067696007 @default.
• W3162128797 cites W2069087118 @default.
• W3162128797 cites W2079136653 @default.
• W3162128797 cites W2088756657 @default.
• W3162128797 cites W2090887099 @default.
• W3162128797 cites W2116277860 @default.
• W3162128797 cites W2125472936 @default.
• W3162128797 cites W2135978944 @default.
• W3162128797 cites W2139505515 @default.
• W3162128797 cites W2143726980 @default.
• W3162128797 cites W2156563057 @default.
• W3162128797 cites W2160048269 @default.
• W3162128797 cites W2169266581 @default.
• W3162128797 cites W2206569935 @default.
• W3162128797 cites W2329082954 @default.
• W3162128797 cites W2400888534 @default.
• W3162128797 cites W2589810159 @default.
• W3162128797 cites W2601562778 @default.
• W3162128797 cites W2607037517 @default.
• W3162128797 cites W2768159192 @default.
• W3162128797 cites W2771371025 @default.
• W3162128797 cites W2805752195 @default.
• W3162128797 cites W2885192633 @default.
• W3162128797 cites W2892280080 @default.
• W3162128797 cites W2892758782 @default.
• W3162128797 cites W2895926103 @default.
• W3162128797 cites W2898230911 @default.
• W3162128797 cites W2909705871 @default.
• W3162128797 cites W2911671599 @default.
• W3162128797 cites W2923049878 @default.
• W3162128797 cites W2937802437 @default.
• W3162128797 cites W2948916079 @default.
• W3162128797 cites W3014713533 @default.
• W3162128797 cites W3026515821 @default.
• W3162128797 cites W3028991244 @default.
• W3162128797 cites W3037511589 @default.
• W3162128797 cites W3088654300 @default.
• W3162128797 cites W2421422963 @default.
• W3162128797 doi "https://doi.org/10.3389/fonc.2021.642902" @default.
• W3162128797 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8149900" @default.
• W3162128797 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34055611" @default.
• W3162128797 hasPublicationYear "2021" @default.
• W3162128797 type Work @default.
• W3162128797 sameAs 3162128797 @default.
• W3162128797 citedByCount "8" @default.
• W3162128797 countsByYear W31621287972021 @default.
• W3162128797 countsByYear W31621287972022 @default.
• W3162128797 countsByYear W31621287972023 @default.
• W3162128797 crossrefType "journal-article" @default.
• W3162128797 hasAuthorship W3162128797A5015845150 @default.
• W3162128797 hasAuthorship W3162128797A5032781939 @default.
• W3162128797 hasAuthorship W3162128797A5053444775 @default.
• W3162128797 hasAuthorship W3162128797A5056741906 @default.
• W3162128797 hasAuthorship W3162128797A5059439308 @default.
• W3162128797 hasAuthorship W3162128797A5071703986 @default.
• W3162128797 hasAuthorship W3162128797A5071802715 @default.
• W3162128797 hasBestOaLocation W31621287971 @default.
• W3162128797 hasConcept C121608353 @default.
• W3162128797 hasConcept C126322002 @default.
• W3162128797 hasConcept C143998085 @default.
• W3162128797 hasConcept C156957248 @default.
• W3162128797 hasConcept C187960798 @default.
• W3162128797 hasConcept C207103383 @default.
• W3162128797 hasConcept C2776478404 @default.
• W3162128797 hasConcept C2780439572 @default.
• W3162128797 hasConcept C44249647 @default.
• W3162128797 hasConcept C526805850 @default.
• W3162128797 hasConcept C71924100 @default.

• next