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- W3162140085 abstract "Autoimmune polyglandular syndromes (APS) are characterized by sequential or simultaneous deciencies in the function of several endocrine glands that have a common cause. Etiology is most often autoimmune.We report a case of a 40-year-old female with diabetes who presented with diabetic ketoacidosis (DKA) and was later diagnosed with T1D. The patient has had a history of hypothyroidism. The presence of vitiligo was an incidental nding.Laboratory investigations showed low C peptide level, glutamic acid decarboxylase (GAD) 65 antibodies positive, thyroid peroxidase antibodies (TPO) positive, parietal cell antibody positive, and weakly positive antinuclear antibody (ANA), amid normal corticotropin(ACTH), parathyroid hormone (PTH) , vitamin B 12 levels, and a negative intrinsic factor antibody. The patient had a history of hypothyroidism, subsequently developed T1D, and had vitiligobut was overlooked. The case highlights the notable absence of recognizing the need to investigate this patient who presented with more than two endocrine diseases for measurement of hormone levels, autoantibodies against affected endocrine glands and recognition of related symptoms and signs, and hence the signicance of history taking, observation, and maintaining a high degree of suspicion." @default.
- W3162140085 created "2021-05-24" @default.
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- W3162140085 date "2021-04-01" @default.
- W3162140085 modified "2023-09-23" @default.
- W3162140085 title "IDENTIFICATION OF AUTOIMMUNE POLYGLANDULAR SYNDROME TYPE 3 IN PATIENT WITH HYPOTHYROIDISM : A CASE REPORT" @default.
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- W3162140085 doi "https://doi.org/10.36106/ijsr/6900772" @default.
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