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- W3162142014 abstract "Vaccination against coronavirus is unprecedented. Despite global effort in developing Coronavirus Disease 2019 (COVID-19) vaccine, accelerated vaccine development may do more harm than good and potentially undermine the trust public has for vaccination.1 Nonetheless, a COVID-19 vaccine is still urgently needed, particularly for vulnerable individuals with high risks for complications and mortality. To balance autonomy, beneficence and non-maleficence, a proper COVID-19 vaccine counselling is needed prior to vaccine administration to individuals until the establishment of the long-term safety of the vaccine. The counselling process should be similar to a normal informed consent2 for treatments instead of the usual implied consent for most vaccination programs. The intention of the counselling proposed is neither anti-vaccination nor deterrence of vaccination but to maintain the public trust for the medical community via open disclosure. Potential benefits of vaccination against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may include reducing the risk of contracting SARS-CoV-2, the duration and severity of symptoms if contracted and mortality. Furthermore, apart from benefiting the individuals, the collective benefit of vaccinated individuals protecting their close contacts through herd immunity should be emphasised. However, the efficacy against mutated strains3 of SARS-CoV-2 is unknown and the neutralising antibodies or the protective effect may decline over time.4 Risks of COVID-19 vaccine include not only the known risks observed in investigational trials, but also unknown moderate-to-long-term risks not uncovered during accelerated phases I-III clinical trials. Again, different types of vaccine may carry different risks. Those with live-attenuated or vectors (ie, adenovirus) carry higher risk for vaccine-associated infection. Vaccines using messenger RNA have never been authorised for human use. This piece of information should be conveyed during counselling. Furthermore, the risks disclosed should be regularly updated according to the newest reports available. The morbidity and mortality of a SARS-CoV-2 infection should be conveyed during the counseling process, ideally individualized according to age and past medical history. No effective alternatives to vaccination should be highlighted. If individuals weigh the risks and benefits and decide not to take the risk for vaccine developed under accelerated process, the correct technique of wearing medical masks5 and hand hygiene6 should be reiterated. Nonetheless, the efficacy of vaccine is never 100% but ranged from 70% to 95%, so facemasks, hand hygiene and social distancing should be still recommended despite being vaccinated. We believe that routine counselling for COVID-19 vaccine may balance autonomy, beneficence and non-maleficence in the context of accelerated vaccine development. The authors have declared no conflicts of interest for this article." @default.
- W3162142014 created "2021-05-24" @default.
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- W3162142014 date "2021-05-17" @default.
- W3162142014 modified "2023-09-26" @default.
- W3162142014 title "Counselling for COVID‐19 vaccine is necessary: Balancing the autonomy, beneficence and non‐maleficence in the context of accelerating vaccine development" @default.
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- W3162142014 doi "https://doi.org/10.1111/ijcp.14015" @default.
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