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- W3162246970 abstract "Gum tragacanth nanoparticles were prepared using a combination of intense ultrasound energy and anti-solvent precipitation methods in this research. Results showed that smaller particles were produced by increasing sonication time. As well, increasing the sonication power led to smaller particles, however, increased aggregation. Accordingly, tragacanth solutions with 0.5 and 1% (w/v) concentrations were prepared and mixed with ethanol (ratio 1:10 v/v) after ultrasound treatment with two different drop-wise and direct methods to investigate the effect of anti-solvent addition method on the precipitation of tragacanth particles. The nanoparticle images showed that the concentration of the 0.5% tragacanth solution and the direct mixing method was suitable for particle production with desirable size (72 ± 10 nm) and uniformity. FTIR, XRD, and STA studies showed that the tragacanth chemical composition did not change, and only its particle size decreased. Investigation of wettability showed a contact angle of 88.9 ± 1.7 degrees for nanoparticles providing partial wetting of the particles at the interface. Investigation of the solution viscosities of 0.5% tragacanth gum and tragacanth nanoparticles showed that the viscosity of the nanoparticles solution was significantly lower than that of the tragacanth (p < 0.05) indicating the intense effect of ultrasonication on this property. It can be concluded that the high viscosity of tragacanth gum is not due to its chemical composition but is due to its complex structure." @default.
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- W3162246970 date "2021-05-07" @default.
- W3162246970 modified "2023-10-18" @default.
- W3162246970 title "Effect of combination of ultrasonic treatment and anti-solvent methods as a high-efficiency method of nanoparticle production on the tragacanth gum properties" @default.
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- W3162246970 doi "https://doi.org/10.1007/s13197-021-05117-1" @default.
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