Matches in SemOpenAlex for { <https://semopenalex.org/work/W3162693969> ?p ?o ?g. }
Showing items 1 to 84 of
84
with 100 items per page.
- W3162693969 abstract "Abstract Neurons are specialized cells in information transmission and information processing. Following this, many neurologic disorders are directly linked not to cellular viability/homeostasis issues but rather to specific anomalies in electrical activity dynamics. Acknowledging this fact, therapeutic strategies based on direct modulation of neuronal electrical activity have been producing remarkable results, with successful examples ranging from cochlear implants to deep brain stimulation. Development on these implantable devices are hindered, however, by important challenges: power requirements, size factor, signal transduction, and adaptability/computational capabilities. Memristors, nanoscale electronic components able to emulate natural synapses, provide unique properties to address these constraints and their use in neuroprosthetic devices is being actively explored. Here we demonstrate for the first time the use of memristive devices in a clinically relevant setting where communication between two neuronal populations is conditioned to specific activity patterns in the source population. In our approach, the memristor device performs a simple pattern detection computation and acts as a synapstor capable of reversible short-term plasticity. Using in vitro hippocampal neuronal cultures, we show real-time adaptive control with a high degree of reproducibility using our monitor-compute-actuate paradigm. We envision very similar systems being used for automatic detection and suppression of seizures in epileptic patients." @default.
- W3162693969 created "2021-05-24" @default.
- W3162693969 creator A5003513755 @default.
- W3162693969 creator A5007921756 @default.
- W3162693969 creator A5025782009 @default.
- W3162693969 creator A5050501477 @default.
- W3162693969 creator A5063415376 @default.
- W3162693969 date "2021-05-21" @default.
- W3162693969 modified "2023-10-18" @default.
- W3162693969 title "A memristor-based neuromodulation device for real-time monitoring and adaptive control of in vitro neuronal populations" @default.
- W3162693969 cites W1862155492 @default.
- W3162693969 cites W1966010951 @default.
- W3162693969 cites W1976342705 @default.
- W3162693969 cites W2016922062 @default.
- W3162693969 cites W2035408474 @default.
- W3162693969 cites W2038593071 @default.
- W3162693969 cites W2043707274 @default.
- W3162693969 cites W2080438790 @default.
- W3162693969 cites W2299269746 @default.
- W3162693969 cites W2389556795 @default.
- W3162693969 cites W2510112518 @default.
- W3162693969 cites W2512274313 @default.
- W3162693969 cites W2599351150 @default.
- W3162693969 cites W2754967293 @default.
- W3162693969 cites W2792208628 @default.
- W3162693969 cites W2899749427 @default.
- W3162693969 cites W2900872097 @default.
- W3162693969 cites W2953991049 @default.
- W3162693969 cites W2963392624 @default.
- W3162693969 cites W3080915835 @default.
- W3162693969 cites W3097116240 @default.
- W3162693969 doi "https://doi.org/10.1101/2021.05.20.444941" @default.
- W3162693969 hasPublicationYear "2021" @default.
- W3162693969 type Work @default.
- W3162693969 sameAs 3162693969 @default.
- W3162693969 citedByCount "0" @default.
- W3162693969 crossrefType "posted-content" @default.
- W3162693969 hasAuthorship W3162693969A5003513755 @default.
- W3162693969 hasAuthorship W3162693969A5007921756 @default.
- W3162693969 hasAuthorship W3162693969A5025782009 @default.
- W3162693969 hasAuthorship W3162693969A5050501477 @default.
- W3162693969 hasAuthorship W3162693969A5063415376 @default.
- W3162693969 hasBestOaLocation W31626939691 @default.
- W3162693969 hasConcept C127413603 @default.
- W3162693969 hasConcept C148762608 @default.
- W3162693969 hasConcept C150072547 @default.
- W3162693969 hasConcept C151927369 @default.
- W3162693969 hasConcept C154945302 @default.
- W3162693969 hasConcept C169760540 @default.
- W3162693969 hasConcept C24326235 @default.
- W3162693969 hasConcept C24998067 @default.
- W3162693969 hasConcept C2780375056 @default.
- W3162693969 hasConcept C41008148 @default.
- W3162693969 hasConcept C50644808 @default.
- W3162693969 hasConcept C86803240 @default.
- W3162693969 hasConceptScore W3162693969C127413603 @default.
- W3162693969 hasConceptScore W3162693969C148762608 @default.
- W3162693969 hasConceptScore W3162693969C150072547 @default.
- W3162693969 hasConceptScore W3162693969C151927369 @default.
- W3162693969 hasConceptScore W3162693969C154945302 @default.
- W3162693969 hasConceptScore W3162693969C169760540 @default.
- W3162693969 hasConceptScore W3162693969C24326235 @default.
- W3162693969 hasConceptScore W3162693969C24998067 @default.
- W3162693969 hasConceptScore W3162693969C2780375056 @default.
- W3162693969 hasConceptScore W3162693969C41008148 @default.
- W3162693969 hasConceptScore W3162693969C50644808 @default.
- W3162693969 hasConceptScore W3162693969C86803240 @default.
- W3162693969 hasLocation W31626939691 @default.
- W3162693969 hasOpenAccess W3162693969 @default.
- W3162693969 hasPrimaryLocation W31626939691 @default.
- W3162693969 hasRelatedWork W12187545 @default.
- W3162693969 hasRelatedWork W13180604 @default.
- W3162693969 hasRelatedWork W13264843 @default.
- W3162693969 hasRelatedWork W1485775 @default.
- W3162693969 hasRelatedWork W3273620 @default.
- W3162693969 hasRelatedWork W5770039 @default.
- W3162693969 hasRelatedWork W712150 @default.
- W3162693969 hasRelatedWork W9024426 @default.
- W3162693969 hasRelatedWork W9602499 @default.
- W3162693969 hasRelatedWork W11600868 @default.
- W3162693969 isParatext "false" @default.
- W3162693969 isRetracted "false" @default.
- W3162693969 magId "3162693969" @default.
- W3162693969 workType "article" @default.