FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3162801404> ?p ?o ?g. }

• W3162801404 abstract "<h3>Background</h3> Acute wheezing attacks are a leading cause of Paediatric Emergency Department (PED) attendances and inpatient admissions and are a considerable burden on the NHS. Almost one-third of children vomit prednisolone in the PED, requiring anti-emetics and repeat dosing. Single-dose dexamethasone (600 mcg/kg or 300 mcg/kg) is a non-inferior alternative to a 3-day course of prednisolone (1 mg/kg), with the added advantage of improved tolerability and potentially reduced cost. Use of Dexamethasone within a structured protocol (which have shown some reduction in medication delivery times and length of stay (LOS)) would likely facilitate tolerability and PED patient flow. <h3>Objectives</h3> This QI intervention aimed to improve Oral Cortico-Steroid (OCS) tolerability, reduce LOS in the emergency department, and reduce OCS drug costs for acute wheeze attendances in a UK PED, while not adversely affecting admissions, re-attendance, or mortality rates. <h3>Methods</h3> The study team reviewed the evidence and implemented a departmental wheeze protocol. OCS type and dose was modified in subsequent years. Standard dosing in 2016 was a 3 day course of prednisolone 1–2mg/kg. This was changed to a single dose of dexamethasone 600 mcg/kg in 2017, then revised again to a single dose Dexamethasone 300 mcg/kg in 2018. To assess the scale of improvement, we retrospectively collected data on attendance records for patients 2–14 years with acute wheeze requiring OCS. We collected data on 100 children who attended PED between October and December for each year (2016, 2017 and 2018). We then assessed OCS tolerability, LOS, OCS drug-cost, and admission, re-attendance, and mortality rates. <h3>Results</h3> Over a 48-month period, we increased OCS tolerability by 67.2%. There was an 85.8% reduction in OCS drug costs, saving £41,553.14. There was no change in the LOS, admission, re-attendance, and mortality rates. <h3>Conclusions</h3> Improved tolerability and substantial cost savings can be achieved by implementing a structured acute paediatric wheeze protocol and modifying the OCS to single- dose dexamethasone (300 mcg/kg)." @default.
• W3162801404 created "2021-05-24" @default.
• W3162801404 creator A5008546299 @default.
• W3162801404 creator A5022921132 @default.
• W3162801404 creator A5026665974 @default.
• W3162801404 creator A5032804379 @default.
• W3162801404 creator A5042674954 @default.
• W3162801404 creator A5046030617 @default.
• W3162801404 creator A5049916711 @default.
• W3162801404 creator A5050680856 @default.
• W3162801404 creator A5057311790 @default.
• W3162801404 creator A5081263186 @default.
• W3162801404 creator A5012820493 @default.
• W3162801404 date "2021-09-30" @default.
• W3162801404 modified "2023-09-26" @default.
• W3162801404 title "586 Puking less per pound, for acute wheezers: quality improvement in a paediatric emergency department" @default.
• W3162801404 doi "https://doi.org/10.1136/archdischild-2021-rcpch.83" @default.
• W3162801404 hasPublicationYear "2021" @default.
• W3162801404 type Work @default.
• W3162801404 sameAs 3162801404 @default.
• W3162801404 citedByCount "0" @default.
• W3162801404 crossrefType "proceedings-article" @default.
• W3162801404 hasAuthorship W3162801404A5008546299 @default.
• W3162801404 hasAuthorship W3162801404A5012820493 @default.
• W3162801404 hasAuthorship W3162801404A5022921132 @default.
• W3162801404 hasAuthorship W3162801404A5026665974 @default.
• W3162801404 hasAuthorship W3162801404A5032804379 @default.
• W3162801404 hasAuthorship W3162801404A5042674954 @default.
• W3162801404 hasAuthorship W3162801404A5046030617 @default.
• W3162801404 hasAuthorship W3162801404A5049916711 @default.
• W3162801404 hasAuthorship W3162801404A5050680856 @default.
• W3162801404 hasAuthorship W3162801404A5057311790 @default.
• W3162801404 hasAuthorship W3162801404A5081263186 @default.
• W3162801404 hasBestOaLocation W31628014041 @default.
• W3162801404 hasConcept C118552586 @default.
• W3162801404 hasConcept C126322002 @default.
• W3162801404 hasConcept C187212893 @default.
• W3162801404 hasConcept C194828623 @default.
• W3162801404 hasConcept C197934379 @default.
• W3162801404 hasConcept C2776715498 @default.
• W3162801404 hasConcept C2777288759 @default.
• W3162801404 hasConcept C2778375690 @default.
• W3162801404 hasConcept C2780401358 @default.
• W3162801404 hasConcept C2780724011 @default.
• W3162801404 hasConcept C71924100 @default.
• W3162801404 hasConceptScore W3162801404C118552586 @default.
• W3162801404 hasConceptScore W3162801404C126322002 @default.
• W3162801404 hasConceptScore W3162801404C187212893 @default.
• W3162801404 hasConceptScore W3162801404C194828623 @default.
• W3162801404 hasConceptScore W3162801404C197934379 @default.
• W3162801404 hasConceptScore W3162801404C2776715498 @default.
• W3162801404 hasConceptScore W3162801404C2777288759 @default.
• W3162801404 hasConceptScore W3162801404C2778375690 @default.
• W3162801404 hasConceptScore W3162801404C2780401358 @default.
• W3162801404 hasConceptScore W3162801404C2780724011 @default.
• W3162801404 hasConceptScore W3162801404C71924100 @default.
• W3162801404 hasLocation W31628014041 @default.
• W3162801404 hasOpenAccess W3162801404 @default.
• W3162801404 hasPrimaryLocation W31628014041 @default.
• W3162801404 hasRelatedWork W2026095104 @default.
• W3162801404 hasRelatedWork W2060426724 @default.
• W3162801404 hasRelatedWork W2061619006 @default.
• W3162801404 hasRelatedWork W2199387204 @default.
• W3162801404 hasRelatedWork W2413958338 @default.
• W3162801404 hasRelatedWork W2510700473 @default.
• W3162801404 hasRelatedWork W2531284920 @default.
• W3162801404 hasRelatedWork W2613637409 @default.
• W3162801404 hasRelatedWork W4232888950 @default.
• W3162801404 hasRelatedWork W4310643346 @default.
• W3162801404 isParatext "false" @default.
• W3162801404 isRetracted "false" @default.
• W3162801404 magId "3162801404" @default.
• W3162801404 workType "article" @default.