FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3163054930> ?p ?o ?g. }

• W3163054930 abstract "Abstract Background The very high burden of rifampicin resistance tuberculosis (RR-TB) and the very low detection of RR-TB cases are a major challenge that China has been facing. This study analyzed the characteristics of RR-TB detection in China after the change of RR-TB detection strategy since 2015, aiming to provide reference and evidence for the development of more precise national drug resistance tuberculosis prevention and control policy. Methods We extracted data related to rifampicin resistance screening from the national Tuberculosis Information Management System (TBIMS) from 2015 to 2019, and used descriptive research methods to analyze the screening rate of presumptive RR-TB, the number and duration of RR-TB patients detected and drug resistance testing methods in each year. Chi-square test was used to compare the differences in component ratio or rate between years, and Kruskal Wallis test was used to compare the differences in median days for detection of RR-TB patients in each year. Results A total of 68,200 RR-TB cases were detected during 2015–2019, of which 48.1% were new cases. The number and detection rate of RR-TB cases increased year by year, from 10 019 and 14.3% in 2015 to 18 623 and 28.7% in 2019, respectively. Of the bacteriologically confirmed TB cases, 81.9% were tested for RR in 2019, a considerable increase from 29.5% in 2015. In 2019, only 41.0% of RR-TB cases had fluoroquinolones (FQs) susceptibility testing performed, and this proportion has been declining year by year since 2016. The proportion of application of rapid molecular tools increased from 24.0% in 2015 to 67.1% in 2019, and the median days to obtain RR results was significantly shortened. In 2019, 76.0% of RR-TB cases were diagnosed as presumptive RR-TB in county-level hospitals. Conclusions After China modified the RR-TB detection strategy, the screening rate of RR and the number of RR-TB cases increased significantly. The RR testing methods now predominantly utilize rapid molecular tools. However, comprehensive measures should be implemented to close the gap in the detection of RR-TB cases. It is imperative to take FQs susceptibility testing seriously and effectively strengthen the laboratory capacity of county-level hospitals. Graphical Abstract" @default.
• W3163054930 created "2021-05-24" @default.
• W3163054930 creator A5033212585 @default.
• W3163054930 creator A5042531041 @default.
• W3163054930 creator A5046711735 @default.
• W3163054930 creator A5059548467 @default.
• W3163054930 creator A5069640391 @default.
• W3163054930 creator A5083797099 @default.
• W3163054930 date "2021-07-17" @default.
• W3163054930 modified "2023-10-16" @default.
• W3163054930 title "Characteristics of rifampicin-resistant tuberculosis detection in China, 2015–2019" @default.
• W3163054930 cites W2087135157 @default.
• W3163054930 cites W2172723300 @default.
• W3163054930 cites W2345334019 @default.
• W3163054930 cites W2345634663 @default.
• W3163054930 cites W2558519010 @default.
• W3163054930 cites W2588581855 @default.
• W3163054930 cites W2591345815 @default.
• W3163054930 cites W2656858203 @default.
• W3163054930 cites W2891690058 @default.
• W3163054930 cites W2907614829 @default.
• W3163054930 cites W2915052082 @default.
• W3163054930 cites W2938724810 @default.
• W3163054930 cites W3012216007 @default.
• W3163054930 cites W3047484884 @default.
• W3163054930 doi "https://doi.org/10.1186/s40249-021-00883-8" @default.
• W3163054930 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8285846" @default.
• W3163054930 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34274020" @default.
• W3163054930 hasPublicationYear "2021" @default.
• W3163054930 type Work @default.
• W3163054930 sameAs 3163054930 @default.
• W3163054930 citedByCount "5" @default.
• W3163054930 countsByYear W31630549302022 @default.
• W3163054930 countsByYear W31630549302023 @default.
• W3163054930 crossrefType "journal-article" @default.
• W3163054930 hasAuthorship W3163054930A5033212585 @default.
• W3163054930 hasAuthorship W3163054930A5042531041 @default.
• W3163054930 hasAuthorship W3163054930A5046711735 @default.
• W3163054930 hasAuthorship W3163054930A5059548467 @default.
• W3163054930 hasAuthorship W3163054930A5069640391 @default.
• W3163054930 hasAuthorship W3163054930A5083797099 @default.
• W3163054930 hasBestOaLocation W31630549301 @default.
• W3163054930 hasConcept C114851261 @default.
• W3163054930 hasConcept C126322002 @default.
• W3163054930 hasConcept C142724271 @default.
• W3163054930 hasConcept C2777975735 @default.
• W3163054930 hasConcept C2778607973 @default.
• W3163054930 hasConcept C2781069245 @default.
• W3163054930 hasConcept C44249647 @default.
• W3163054930 hasConcept C71924100 @default.
• W3163054930 hasConcept C82789193 @default.
• W3163054930 hasConcept C86803240 @default.
• W3163054930 hasConcept C89423630 @default.
• W3163054930 hasConceptScore W3163054930C114851261 @default.
• W3163054930 hasConceptScore W3163054930C126322002 @default.
• W3163054930 hasConceptScore W3163054930C142724271 @default.
• W3163054930 hasConceptScore W3163054930C2777975735 @default.
• W3163054930 hasConceptScore W3163054930C2778607973 @default.
• W3163054930 hasConceptScore W3163054930C2781069245 @default.
• W3163054930 hasConceptScore W3163054930C44249647 @default.
• W3163054930 hasConceptScore W3163054930C71924100 @default.
• W3163054930 hasConceptScore W3163054930C82789193 @default.
• W3163054930 hasConceptScore W3163054930C86803240 @default.
• W3163054930 hasConceptScore W3163054930C89423630 @default.
• W3163054930 hasIssue "1" @default.
• W3163054930 hasLocation W31630549301 @default.
• W3163054930 hasLocation W31630549302 @default.
• W3163054930 hasLocation W31630549303 @default.
• W3163054930 hasLocation W31630549304 @default.
• W3163054930 hasOpenAccess W3163054930 @default.
• W3163054930 hasPrimaryLocation W31630549301 @default.
• W3163054930 hasRelatedWork W1580863111 @default.
• W3163054930 hasRelatedWork W1896292939 @default.
• W3163054930 hasRelatedWork W2119921379 @default.
• W3163054930 hasRelatedWork W2140892120 @default.
• W3163054930 hasRelatedWork W2154249854 @default.
• W3163054930 hasRelatedWork W2358903681 @default.
• W3163054930 hasRelatedWork W2370070129 @default.
• W3163054930 hasRelatedWork W2546518088 @default.
• W3163054930 hasRelatedWork W4310811299 @default.
• W3163054930 hasRelatedWork W652003262 @default.
• W3163054930 hasVolume "10" @default.
• W3163054930 isParatext "false" @default.
• W3163054930 isRetracted "false" @default.
• W3163054930 magId "3163054930" @default.
• W3163054930 workType "article" @default.