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- W3163094891 abstract "To determine whether magnetoencephalography (MEG) can identify epileptiform discharges mimicking small sharp spikes (SSSs) on scalp electroencephalography (EEG) in patients with temporal lobe epilepsy (TLE). We retrospectively reviewed simultaneous scalp EEG and MEG recordings of 83 consecutive patients with TLE and 49 with extra-TLE (ETLE). SSSs in scalp EEG were detected in 15 (18.1%) of 83 TLE patients compared to only two (4.1%) of 49 ETLE patients (p = 0.029). Five of the 15 TLE patients had MEG spikes with concurrent SSSs in EEG, but neither of the 2 ETLE patients. Three of these 5 TLE patients had additional interictal epileptiform discharges (IEDs) in EEG and MEG. Equivalent current dipoles (ECDs) of MEG spikes with concurrent SSSs and IEDs showed no difference in temporal lobe localization and horizontal orientation, whereas ECD moments were smaller in MEG spikes with concurrent SSSs than those with IEDs. SSSs were more common in TLE than in ETLE. At least some morphologically diagnosed SSSs are true but low-amplitude epileptiform discharges in TLE which can be identified with simultaneous MEG. Simultaneous MEG is useful to identify epileptiform discharges mimicking SSSs in patients with TLE." @default.
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- W3163094891 date "2021-08-01" @default.
- W3163094891 modified "2023-10-14" @default.
- W3163094891 title "Magnetoencephalography to confirm epileptiform discharges mimicking small sharp spikes in temporal lobe epilepsy" @default.
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- W3163094891 doi "https://doi.org/10.1016/j.clinph.2021.03.049" @default.
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