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• W3163204739 startingPage "106536" @default.
• W3163204739 abstract "• Bending the flexible surface acoustic wave devices in concave or convex geometries will cause the particle pattern lines to converge towards or diverge away from the centre of the curvature of the geometry. • Particle patterning is more efficient on Lamb wave devices compared to and Rayleigh wave devices with the same concave geometry. • For the same convex geometry, the particle patterning is more clear and regular on Rayleigh wave devices compared to Lamb wave devices. • Twisting the flexible surface acoustic wave devices deforms the IDTs and the particles pattern into lines parallel to the inclined direction of the twisted IDTs. • Manipulating and patterning yeast cells using our flexible surface acoustic wave devices demonstrates the possibility of applying our flexible acoustofluidic systems into biomedical applications . Surface Acoustic Wave (SAW) based microfluidic devices provide active techniques to manipulate fluid and particles, which can be used for precise and controllable patterning of microparticles and biological cells, with a high efficiency in a non-invasive and contact-free manner. This paper investigates flexible and bendable SAW microfluidic devices and explores the effects of bending and twisting of SAW devices on microparticle and cell patterning, using both experimental and numerical modelling. We showed that bending flexible SAW devices changes the distribution of particle pattern lines significantly. In devices with concave bending the particle pattern lines converge towards the centre of the curvature, whereas for devices with convex bending, they diverge away from it. Comparing the particle patterning using Lamb and Rayleigh wave devices with concave bending, we found that particle alignment is more efficient in the flexural mode Lamb wave device, whereas for the devices with convex bending, the particle patterning is more clear and regular when Rayleigh waves are used. We further investigated the effects of twisting the flexible SAW devices and observed that the particles are patterned into lines parallel to the deformed interdigital transducers (IDTs). We finally patterned yeast cells using our flexible SAW devices, and demonstrated the possibility of using our flexible acoustofluidic device for biomechanical systems such as body conforming technologies, wearable bio-sensors, and flexible point-of-care devices for personalized health monitoring." @default.
• W3163204739 created "2021-05-24" @default.
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• W3163204739 date "2021-07-01" @default.
• W3163204739 modified "2023-10-15" @default.
• W3163204739 title "Flexible and bendable acoustofluidics for particle and cell patterning" @default.
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• W3163204739 doi "https://doi.org/10.1016/j.ijmecsci.2021.106536" @default.
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